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posted by martyb on Thursday September 03 2020, @12:49AM   Printer-friendly
from the https://xkcd.com/1217/ dept.

A Molecule in Honeybee Venom Destroys Breast Cancer Cells in The Lab, Study Shows:

The study focussed(sic) on certain subtypes of breast cancer, including triple-negative breast cancer (TNBC), which is an extremely aggressive condition with limited treatment options.

TNBC accounts for up to 15 percent of all breast cancers. In many cases, its cells produce more of a molecule called EGFR than seen in normal cells. Previous attempts to develop treatments that specifically target this molecule have not worked, because they would also negatively affect healthy cells.

[...] Bees actually use melittin - the molecule that makes up half of their venom and makes their stings really hecking painful - to fight off their own pathogens. The insects produce this peptide not just in their venom, but in other tissues too, where it's expressed in response to infections.

[...] "The venom was extremely potent," said medical researcher Ciara Duffy from The Harry Perkins Institute of Medical Research. "We found that melittin can completely destroy cancer cell membranes within 60 minutes."

When melittin was blocked with an antibody, the cancer cells exposed to the bee venom survived - showing that melittin was indeed the venom component responsible for the results in the earlier trials.

The best part: melittin had little impact on normal cells, specifically targeting cells that produced a lot of EGFR and HER2 (another molecule excessively produced by some breast cancer types); it even messed with the cancer cells' ability to replicate.

[...] Taking their conclusions even further, the research team also produced a synthetic version of melittin, to see how it would perform compared to the real deal.

"We found that the synthetic product mirrored the majority of the anti-cancer effects of honeybee venom," Duffy said.

Journal Reference:
Ciara Duffy, Anabel Sorolla, Edina Wang, et al. Honeybee venom and melittin suppress growth factor receptor activation in HER2-enriched and triple-negative breast cancer [open], npj Precision Oncology (DOI: 10.1038/s41698-020-00129-0)


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  • (Score: -1, Spam) by Anonymous Coward on Thursday September 03 2020, @01:31AM

    by Anonymous Coward on Thursday September 03 2020, @01:31AM (#1045682)

    "I think it was a bee" Mark replied

    "Well I'm gonna have to get the sting out then"

    "How'd you do that?" Mark asked knowing full well how it
    was done.

    "You have to suck it out" Mandy replied, another
    pleasurable sensation shot through her as she thought of
    her lips sucking on her son's tender skin, she tightened
    her grip on the back of her son's leg trying to get a hold
    of herself. She moved her head in close, parting her pouty
    lips she pushed them down over the bite, his hairs tickling
    her nose,.

    Mark let out a little gasp as his mom's lips touched his
    skin, his cock flexed again, some pre-cum was forming on
    the tip, his dick was aching, his mom bent in closer to his
    thigh, her breasts rubbing againest the inside of his shin
    as she tryed to work the imaginary bee sting out from his
    skin.

    Mandy was sucking hard, her wet lips pressed tightly to her
    son's leg, she pressed her tongue onto the swollen bump,
    she felt her breasts rubbing againest Mark's lower leg, her
    sensitive nipples hardened becuase of it, she unconciously
    moved her other hand a little further up the back of her
    son's leg, cupping the bottom of his ass cheek.

    Mandy started to rock her body againest her son's leg, her
    pussy throbbing with desire, she took her lips away from
    his swollen lump, but ran her hot, wet tongue over it,
    leaving a trail of saliva behind, she had't felt anything
    pop out the sting but maybe she'd done the job, she looked
    up at her son, but all she could see was her son's cock
    looming over her, she saw the sticky pre-cum leaking from
    the end of his cockhead, showing up clearly againest the
    deep purple.

    "Ohh!" Mandy really could't help herself, the little moan
    escaped from her lips as she looked over her son's cock, he
    was obviously very turned on by her actions but she felt
    some guilt also, she should't have got herself into this
    position, he was her son, her flesh and blood but still her
    body ached.

    "You finished mom? It feels a whole lot better." Mark
    said.

    "Good honey" she was still looking at his cock, she started
    to rub her hand over his bottom, feeling his hard ass
    cheeks.

    "But I've got something else that could do with suckin as
    well" Mark looked down at his mom, he took his hand and ran
    it through her hair, he moved his hand to the back of her
    head and lightly took hold of her hair, pulling her up
    slightly to the level of his cock, her full, red pouty lips
    were barely an inch away from his cock as it jerked about,
    waving in front of her face, the pre-cum dribbling down the
    front of the full cockhead.

    Mandy did't hesistate she opened her mouth, and ran her
    tongue along her son's cockhead, licking the white sperm
    from it, she raised her hand and gripped his cock shaft
    tightly, she tugged on it, pulling his foreskin back and
    forth, more pre-cum appeared on the tip and again she shot
    her tongue out and licked away the white droplets.

    "Ugghhhh!" Mark moaned as his mother ran her tongue along
    the shaft and back again, he pushed her head towards his
    dick, Mandy opened her mouth wide and took her son's huge
    cock into her mouth, she felt it hit the back of her throat
    almost and she started to suck on it extremely hard, her
    hand pulling his fore skin back and forth as she did.
    Mandy closed her eyes tight, tasting her son's hot prick as
    she ran her tongue across the bottom of it.

    "Uughh Mom! Suck It" Mark urged, his dick pulsing in his
    own mothers mouth, he gripped the back of her head tighter
    as she eagerly sucked his cock, bobbing her head back and
    forth in a fast rhytm.

    Mandy was't thinking about anything else but sucking her
    son's cock, she gripped his cockshaft tighter, working it
    faster.

    It was to much for Mark, he looked down watching his mom
    suck on his hard meat, he could feel her wet saliva all
    over the shaft, he was meeting her bobbing head with his
    own small thrusts, rocking his hips back and forth.

    "Mom I'm gonna cum!!" he moaned, he felt his cum-sac
    welling up with his spunk

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