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posted by cmn32480 on Monday May 04 2015, @12:39AM   Printer-friendly
from the just-gimme-the-damn-pill dept.

Precision medicine requires a different type of clinical trial that focuses on individual, not average, responses to therapy, says Nicholas J. Schork.

Every day, millions of people are taking medications that will not help them. The top ten highest-grossing drugs in the United States help between 1 in 25 and 1 in 4 of the people who take them (see 'Imprecision medicine' ). For some drugs, such as statins — routinely used to lower cholesterol — as few as 1 in 50 may benefit. There are even drugs that are harmful to certain ethnic groups because of the bias towards white Western participants in classical clinical trials.

Recognition that physicians need to take individual variability into account is driving huge interest in 'precision' medicine. In January, US President Barack Obama announced a US$215-million national Precision Medicine Initiative. This includes, among other things, the establishment of a national database of the genetic and other data of one million people in the United States.

http://www.nature.com/news/personalized-medicine-time-for-one-person-trials-1.17411

 
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  • (Score: 0) by Anonymous Coward on Monday May 04 2015, @05:33AM

    by Anonymous Coward on Monday May 04 2015, @05:33AM (#178328)

    And success at a "one person trial" is not evidence of effectiveness, it is testimony!

    Evidence: the available body of facts or information indicating whether a belief or proposition is true or valid.
    Testimony: evidence or proof provided by the existence or appearance of something

    therapy has to be adjusted for individuals, all we can say is, "duh!" What did you think was going on?

    success at a "one person trial" is not evidence of effectiveness

    But it's not science, and no evidence for actual medicine

    Go home aristy-poo, you're drunk.

  • (Score: 2) by aristarchus on Monday May 04 2015, @05:53AM

    by aristarchus (2645) on Monday May 04 2015, @05:53AM (#178332) Journal

    Au contraire, mes ami! Testimony is one idiot saying what they think. It is not evidence. For there to be evidence, we need a lot of idiots all testifying, so that by using logic we can assertain the truth. Do you have a problem with that? Testimony is not, by itself, evidence, and certainly not proof. Unless you live in the Southern States of America, and the perpetrator was Black.

    • (Score: 1, Offtopic) by c0lo on Monday May 04 2015, @10:13AM

      by c0lo (156) Subscriber Badge on Monday May 04 2015, @10:13AM (#178407) Journal

      Testimony is one idiot saying what they think.

      Nope: "one idiot saying what they think" is a multiple personalities sufferer [youtube.com] enjoying the freedom of speech.

      --
      https://www.youtube.com/watch?v=aoFiw2jMy-0 https://soylentnews.org/~MichaelDavidCrawford
    • (Score: 0) by Anonymous Coward on Monday May 04 2015, @11:03AM

      by Anonymous Coward on Monday May 04 2015, @11:03AM (#178419)

      Billions of people testify as to the existence of God, therefore Aristarchus has evidence that God exists.

      The faithful rejoice.