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New strategy to halt HIV growth: block its sugar and nutrient pipeline. HIV has a voracious sweet tooth, which turns out to be its Achilles' heel, reports a new study from Northwestern Medicine and Vanderbilt University.
After the virus invades an activated immune cell, it craves sugar and nutrients from the cell to replicate and fuel its wild growth throughout the body.
Scientists discovered the switch that turns on the immune cell's abundant sugar and nutrient pipeline. Then they blocked the switch with an experimental compound, shutting down the pipeline, and, thereby, starving HIV to death. The virus was unable to replicate in human cells in vitro.
The discovery may have applications in treating cancer, which also has an immense appetite for sugar and other nutrients in the cell, which it needs to grow and spread.
http://www.northwestern.edu/newscenter/stories/2015/05/hivs-sweet-tooth-is-its-downfall.html
[Abstract]: http://journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1004864
Original Submission
(Score: 2) by HiThere on Monday June 01 2015, @07:21PM
FWIW, I tried an Atkins-ish diet for about 6 months. Afterwards my triglycerides levels were a *lot* higher. This was not a desirable change, even though I did lose weight on it.
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(Score: 2) by q.kontinuum on Monday June 01 2015, @08:39PM
May I ask how Atkins-ish your diet was? I'm trying to limit my meat-consumption and focus on healthy fat, like olives, fish, olive-oil, linen-seeds, cottage-cheese etc. I do eat meat, but try not to fall for the common misconception that Atkins is meat only.
Beside that, I don't usually don't discuss the details at length with larger communities, so I don't know how common it is to not get along with Atkins. I know some people have difficulties, and some swear they can only lose weight on low-fat diet, not on low-carb.
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(Score: 2) by HiThere on Tuesday June 02 2015, @07:56PM
Very high in meats, very low in carbohydrates, except for things like broccoli, etc. Beans pretty much ok, but limited. Cabbage, brussel sprouts, etc. ok. Sugar only in fruit, and then in extreme moderation.
The meat was largely low fat cuts. For reasons of economy this meant a lot of chicken and turkey. Perhaps beef every third day. Fish at least once a week. (It's been awhile, and I don't usually categorize this way, so this is a bit vague.) Lots of eggs and cheese (but low carb cheeses only).
I've nearly turned that on it's head, though not quite. I'm now nearly vegetarian except for eggs and fish. Sugar is still quite limited, though, and I keep trying to also limit starches...but not to the extent that I did on the atkinsish diet. Beans has become a mainstay. The problem is satisfaction is more difficult. Also interesting greens tend to be seasonal. Since I'm also trying to keep a generally low salt diet (which I also had before) this make things difficult. Frozen and canned foods generally have totally unreasonable amounts of salt added. There are some exceptions, but that means limited choices. (And it's made the worse because I really don't like thinking about what I'm going to eat. It's not only unattractive to me, it tends to make me hungry.)
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