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posted by janrinok on Tuesday July 21 2015, @03:57PM   Printer-friendly
from the I-thought-the-answer-was-42 dept.

Amino acids are just what their name implies: they have an acidic group on one side of the molecule and a nitrogen-containing amino group on the other. It's possible to link these two groups together in a reaction that releases a water molecule. Once linked, they're stable, but the reaction that links them isn't energetically favorable. So, people pondering the origin of life have wondered whether there was a pathway in which the bond could could form spontaneously.

One possible method for getting it to form would be for a solution of amino acids to dry out. As the solution becomes ever more concentrated, a reaction that produces a water molecule could become favorable even if it's expensive in purely energetic terms. But so far, the reaction conditions to get this to work have been rather extreme.

The researchers involved in the new work figured that the amino acids might be alone in these puddles as they dried out. A related chemical, called lactic acid, is thought to have been present on the early Earth. And that can undergo a polymerization reaction that releases water, very similar to that of the amino acids. The difference is that this reaction is more energetically favorable. Simply putting lactic acid on its own through four wet/dry cycles allowed chains of four or more units to form, all connected by what's called an ester bond.

The impressive part is what happens when you mix lactic acid with an amino acid: you start forming mixed chains of molecules. While the amino acid won't normally participate in these reactions, they can break the ester bond, essentially replacing one of the lactic acids. So, a few wet/dry cycles produces a chain that's a mix of lactic acids and amino acids.

The skirt of a geyser would be one place with frequent wet/dry cycles and plenty energy to boot. Did life begin next to Old Faithful?


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  • (Score: 2) by c0lo on Tuesday July 21 2015, @10:52PM

    by c0lo (156) Subscriber Badge on Tuesday July 21 2015, @10:52PM (#212120) Journal

    Still polymerizing your own lactic acid is interesting to think about.

    Wikipedia entry on PLA [wikipedia.org]:

    The most common route to PLA is the ring-opening polymerization of lactide with various metal catalysts (typically tin octoate) in solution, in the melt, or as a suspension. The metal-catalyzed reaction tends to cause racemization of the PLA, reducing its stereoregularity compared to the starting material

    Another route to PLA is the direct condensation of lactic acid monomers. This process needs to be carried out at less than 200 °C; above that temperature, the entropically favored lactide monomer is generated. This reaction generates one equivalent of water for every condensation (esterification) step, and that is undesirable because water causes chain-transfer leading to low molecular weight material.

    Seems that polymerizing your own lactic acid will required 200°C under mild vaccum to get rid of the water generated in the reaction.

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