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takyon [soylentnews.org] writes:

Stem cell transplant 'game changer' for MS patients [bbc.com]

Doctors say a stem cell transplant could be a "game changer" for many patients with multiple sclerosis. Results from an international trial show that it was able to stop the disease and improve symptoms. It involves wiping out a patient's immune system using cancer drugs and then rebooting it with a stem cell transplant.

Louise Willetts, 36, from Rotherham, is now symptom-free and told me: "It feels like a miracle." A total of 100,000 people in the UK have MS, which attacks nerves in the brain and spinal cord.

Counterpoint [futurism.com]:

There are just a few problems, however: The experimental procedure is under scrutiny from regulators, the experiment's web site may have overstated the effectiveness of the not-yet-proven treatment, and patients have to foot the bill. Oh, and no one has seen the study yet.

[...] The results reported in the BBC piece are just the preliminary findings. And that leaves a number of questions still unanswered — are these results permanent? What are the risks? Who isn't suited to have their immune system wiped out through aggressive chemo?

The U.S. Food and Drug Administration (FDA) has also flagged some serious issues in the study's protocol. If that sounds boring and bureaucratic, think of it this way: for a few months, the lead investigator somehow forgot to report a number of nasty side effects of the treatment [fda.gov], including chest infection and the worsening of conditions as diverse as vertigo, narcolepsy, stuttering, and hyperglycemia, among others.

One thing we know for sure? It's real expensive. The BBC noted it cost patients £30,000 ($42,000) to receive the experimental treatment, but biomedical scientist and science writer Paul Knoepfler, who has been following the trial since last year, says it ran some patients between $100,000 [ipscell.com] and $200,000.

Related: Low Vitamin-D Genes Linked to Multiple Sclerosis [soylentnews.org]
Scientists Identify Potential Inhibitors of Cancer Metastasis and MS [soylentnews.org]
Risky Stem Cell Treatment Reverses MS in 70% of Patients in Small Study [soylentnews.org]

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