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posted by mrpg on Tuesday May 01 2018, @12:34PM   Printer-friendly
from the good-luck! dept.

UC San Diego to use controversial marijuana compound to treat severe autism

UC San Diego will try to alleviate severe autism in children by giving them a non-psychoactive chemical found in marijuana, a project funded by the biggest private donation ever made in the U.S. for such research.

The $4.7 million study involves the controversial compound cannabidiol, or CBD, which is widely marketed nationwide as something of a miracle drug, capable of treating everything from cancer to post-traumatic stress disorder.

[...] UC San Diego dealt with the issue by asking the Ray and Tye Noorda Foundation of Lindon, Utah, for $4.7 million to study whether CBD can ease the most severe symptoms of autism, including seizures, self-injuring behavior, and crippling anxiety. The foundation agreed, and it is urging the federal government to remove marijuana from its list of Schedule 1 drugs so that cannabis can be widely studied.

Related: 4/20: The Mary Jane Majority
US experts back marijuana-based drug for childhood seizures

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4/20: The Mary Jane Majority 56 comments

Past articles: 201520162017 👀

U.S. Senate Minority Leader Chuck Schumer (D-NY) has come out in support of federal cannabis decriminalization, just in time for 4/20:

The Minority Leader of the Senate is making it official the day before 4/20: He's down with legal weed. In an exclusive interview with VICE News, Sen. Chuck Schumer (D-NY) confirmed he is putting his name on legislation that he said is aimed at "decriminalizing" marijuana at the federal level. For Schumer, this is a shift. While he has backed medical marijuana and the rights of states to experiment with legal sales of pot, what he is proposing is a seismic shift in federal drug policy.

"Ultimately, it's the right thing to do. Freedom. If smoking marijuana doesn't hurt anybody else, why shouldn't we allow people to do it and not make it criminal?" Schumer said.

The legislation should be available within a week or so, and would remove cannabis (still listed as "Marihuana") from the Drug Enforcement Administration's list of Schedule I substances. States would then be free to regulate or continue to prohibit the plant. Cannabis advertising would be regulated as are alcohol and tobacco advertising. (Also at NPR, CNN, The Washington Post, and CNBC, as well as Reason taking a shot at Schumer for not doing it sooner.)

A majority of Americans support the legalization of cannabis, including, for the first time, a majority (51%) of Republicans, according to Gallup. Nine states and the District of Columbia have legalized cannabis for recreational use. 29 states, D.C., Guam, and Puerto Rico have legalized medical use of cannabis, and another 17 states have legalized the use of cannabidiol (CBD). Cannabis became available for recreational purposes in California on January 1.

FDA Approves Cannabidiol (CBD) as a Drug, DEA Reclassification Expected Soon 24 comments

FDA approves country's first medicine made from marijuana

The Food and Drug Administration on Monday approved the country's first drug derived from marijuana, a medication that treats two rare and devastating forms of epilepsy.

The drug, GW Pharmaceuticals' Epidiolex, is made of cannabidiol, or CBD, a component of marijuana that does not give users a high. It is given as an oil, and in clinical trials, it was shown to reduce the number of seizures by about 40 percent in patients with Dravet or Lennox-Gastaut syndromes.

"This approval serves as a reminder that advancing sound development programs that properly evaluate active ingredients contained in marijuana can lead to important medical therapies," FDA Commissioner Scott Gottlieb said in a statement. "And, the FDA is committed to this kind of careful scientific research and drug development."

The FDA's decision was expected. FDA officials had indicated they supported approving Epidiolex, and an advisory panel had unanimously recommended it get the green light. There was some concern about the drug's effects on the liver, but experts have said this risk could be addressed by doctors as they monitor their patients during treatment.

Before GW can market Epidiolex, though, the Drug Enforcement Administration will have to reclassify CBD, which in this case, because it comes from marijuana, is considered a Schedule I drug, meaning it has no medical value and a high risk of abuse. The agency is expected to do so within 90 days.

Cannabidiol (CBD).

Also at TechCrunch.

Related: FDA Cracking Down on Unsubstantiated Cannabidiol Health Claims
World Health Organization Clashes With DEA on CBD; CBD May be an Effective Treatment for Psychosis
UC San Diego to Treat Autism Using Cannabidiol

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  • (Score: 1, Interesting) by Anonymous Coward on Tuesday May 01 2018, @02:12PM

    by Anonymous Coward on Tuesday May 01 2018, @02:12PM (#674137)

    We've been treating some severe symptoms of ASD with Marinol (dronabinol) for a couple of years now. It's nothing like a cure for ASD, but it can help to defuse some of the more challenging situations with our 18 year old son. We tried it as a daily dose, that wasn't really helpful - set a new baseline and things were just as bad as before after a while, and worse if you missed the dose. When used "as needed" it tends to take everyone's stress level down a couple notches within 10-30 minutes, even people who aren't taking it.

    It also works well for mom to lower her cortisol levels, on the same kind of "as needed" basis. Unfortunately, dad can't afford to fail a whiz quiz at work, so he's stuck with alcohol as a stress reliever - definitely not good when overused, but semi-effective in small occasional doses.

  • (Score: 2) by DannyB on Tuesday May 01 2018, @04:21PM

    by DannyB (5839) Subscriber Badge on Tuesday May 01 2018, @04:21PM (#674190) Journal

    I can understand treating severe cases.

    If you have a touch of autism or aspergers or something like that, and are high functioning, well, guess what? People pay good money for the things you can hyper-focus on!

    Being good at social interaction isn't everything. But don't eat your coworkers.

    With modern TVs you don't have to worry about braking the yolk on the back of the picture tube.
  • (Score: 0) by Anonymous Coward on Tuesday May 01 2018, @06:00PM (3 children)

    by Anonymous Coward on Tuesday May 01 2018, @06:00PM (#674234)

    after removing weed from schedule 1, we need to arrest all the scum that have been persecuting people under unconstitutional drug laws, including the whores in the legislatures. These pieces of shit have been allowed to destroy the country for far too long.

    • (Score: 1, Insightful) by Anonymous Coward on Tuesday May 01 2018, @06:42PM

      by Anonymous Coward on Tuesday May 01 2018, @06:42PM (#674256)

      That's fine, because you like to talk all about action but will just end up getting high and doing jack shit as usual.

    • (Score: 3, Insightful) by JoeMerchant on Tuesday May 01 2018, @07:02PM

      by JoeMerchant (3937) on Tuesday May 01 2018, @07:02PM (#674264)

      we need to arrest all the scum that have been persecuting people under unconstitutional drug laws, including the whores in the legislatures. These pieces of shit have been allowed to destroy the country for far too long.

      That would be called: Revolution, and is unlikely to pass the legislature.

      🌻🌻 []
    • (Score: 3, Insightful) by takyon on Tuesday May 01 2018, @07:40PM

      by takyon (881) <reversethis-{gro ... s} {ta} {noykat}> on Tuesday May 01 2018, @07:40PM (#674280) Journal

      Right after we nab the war criminals and other violators of civil liberties, including FBI/NSA/CIA agents, local cops, etc.

      Face it, history is written and performed by the winners and you aren't one.

      Even if you formed a concrete plan to forcefully impose your will on said "whores", you would have little effect and be regarded as a lone wulf, nutjob, terrorist, or have your multi-user plot be disrupted by FBI snitches. Things have to get a lot worse economically for the middle class before shit really hits tha fan in an uncontainable way.

      [SIG] 10/28/2017: Soylent Upgrade v14 []