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posted by mrpg on Tuesday July 17 2018, @03:01AM   Printer-friendly
from the I-predict dept.

Submitted via IRC for takyon

The problem is that with so many drugs currently on the U.S. pharmaceutical market, "it's practically impossible to test a new drug in combination with all other drugs, because just for one drug, that would be five thousand new experiments," said Marinka Zitnik, a postdoctoral fellow in computer science and lead author of a paper presented July 10 at the 2018 meeting of the International Society for Computational Biology.

[...] So Zitnik and associates created a network describing how the more than 19,000 proteins in our bodies interact with each other and how different drugs affect these proteins. Using more than 4 million known associations between drugs and side effects, the team then designed a method to identify patterns in how side effects arise, based on how drugs target different proteins, and also to infer patterns about drug-interaction side effects.

Source: How to predict the side effects of millions of drug combinations


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  • (Score: 1, Insightful) by Anonymous Coward on Tuesday July 17 2018, @03:06AM

    by Anonymous Coward on Tuesday July 17 2018, @03:06AM (#708193)

    Clinical trials are going on as we speak... being tested on all of us who are under multi-drug regimens.

    Eventually, statistics will show interaction probabilities.

  • (Score: 2) by ilPapa on Tuesday July 17 2018, @03:25AM (1 child)

    by ilPapa (2366) on Tuesday July 17 2018, @03:25AM (#708196) Journal

    How to Predict the Side Effects of Millions of Drug Combinations

    I'm too high to read the article, but my guess is that you just gotta keep at it, you know. But be sure to stay hydrated and get a rubber mouth guard or you'll grind your teeth down to stubs.

    --
    You are still welcome on my lawn.
    • (Score: 2) by c0lo on Tuesday July 17 2018, @04:30AM

      by c0lo (156) Subscriber Badge on Tuesday July 17 2018, @04:30AM (#708209) Journal

      If it's not AI-with-b(ol)locks-chain then it's not worth it, nobody is going to grant any money for it.

      --
      https://www.youtube.com/watch?v=aoFiw2jMy-0 https://soylentnews.org/~MichaelDavidCrawford
  • (Score: 0) by Anonymous Coward on Tuesday July 17 2018, @05:19AM

    by Anonymous Coward on Tuesday July 17 2018, @05:19AM (#708217)

    Does this work for high weed, medium weed, ditch weed, low weed, and no weed folk? What if instead of weed I put sugar?

  • (Score: 0) by Anonymous Coward on Tuesday July 17 2018, @10:36AM

    by Anonymous Coward on Tuesday July 17 2018, @10:36AM (#708267)

    ... just reading Freak Brothers comics is the best way of predicting the effects of most combinations.

  • (Score: 2) by DannyB on Tuesday July 17 2018, @01:55PM

    by DannyB (5839) Subscriber Badge on Tuesday July 17 2018, @01:55PM (#708327) Journal

    Do less drug testing for interactions.

    If there are side effects, then there is probably some other drug to treat the side effects. Then repeat.

    This public service message brought to you by Big Pharma. Helping to make you more numb while enriching ourselves.

    --
    To transfer files: right-click on file, pick Copy. Unplug mouse, plug mouse into other computer. Right-click, paste.
  • (Score: 0) by Anonymous Coward on Wednesday July 18 2018, @01:42PM

    by Anonymous Coward on Wednesday July 18 2018, @01:42PM (#708758)

    This reminds me of something--

    "In theory, there is no difference between theory and practice. In practice, there is."

    It sounds a lot like a theory-based system.

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