Submitted via IRC for Bytram
3-in-1 vaccine against traveler's diarrhea
A first-ever vaccine designed to deliver a one-two-three punch against the main causes of traveller's diarrhea worldwide may result from new research published by a University of Guelph chemist.
Prof. Mario Monteiro says his novel three-in-one approach to developing a new vaccine could also save lives in developing countries, where it's estimated that these three common pathogens kill more than 100,000 children under age five each year.
His research was recently published in the journal Vaccine.
The paper discusses Monteiro's so-called conjugate vaccine that yokes together proteins from pathogenic E. coli with sugars from Shigella and Campylobacter jejuni. All three bugs are major causes of bacterial diarrhea globally.
In tests with mice, the vaccine provided immunity against all three pathogens.
Evaluation of a conjugate vaccine platform against enterotoxigenic Escherichia coli (ETEC), Campylobacter jejuni and Shigella. Vaccine, 2018; DOI: 10.1016/j.vaccine.2018.09.052
(Score: 0) by Anonymous Coward on Saturday October 13 2018, @03:26AM
Autism vs. traveler's diarrhea
( ͡° ͜ʖ ͡°)
(Score: 1, Interesting) by Anonymous Coward on Saturday October 13 2018, @04:24AM (1 child)
Diarrhea builds character.
(Score: 2, Funny) by Anonymous Coward on Saturday October 13 2018, @11:12AM
I built some character last week: stomach troubles had left my bum a bit sensitive. The last day of the trip included a dip in the Dead Sea. You are warned not to shave before entering the super salty solution, but this caught me completely off guard!
(Score: 2) by Azuma Hazuki on Saturday October 13 2018, @05:40AM (3 children)
This sounds encouraging, since there's little risk of actually giving someone an infection with said organisms; rather, it looks to prime the immune system against their secretions. IIRC this is how the tetanus shot works, and that's one of the more effective ones I know of. Good to see this happening, especially because of how many peopel diarrhea kills and how horribly, something very few Americans truly understand...
I am "that girl" your mother warned you about...
(Score: 2) by Kilo110 on Saturday October 13 2018, @07:33AM (1 child)
"something very few Americans truly understand..."
sadly it's become better known in certain communities
https://arstechnica.com/science/2018/01/fear-tap-water-is-a-toxic-plot-to-control-your-mind-heres-the-water-for-you/ [arstechnica.com]
(Score: 0) by Anonymous Coward on Saturday October 13 2018, @09:06AM
https://www.youtube.com/watch?v=Qr2bSL5VQgM [youtube.com]
(Score: 0) by Anonymous Coward on Saturday October 13 2018, @09:02AM
Infant mortality is the #1 reason for high birth rates.
(Score: 3, Informative) by Bobs on Saturday October 13 2018, @12:11PM
who has to run studies of hundreds of mice with diarrhea.
Apropos:
“It is a dirty job, but somebody’s got to do it.”
(Score: 2) by VLM on Saturday October 13 2018, @12:38PM
The problem with this is the same problem irradiated ground beef has... now you can safely eat shit; but why would you want to? Leading to the logical pressure to avoid those products/areas.
(Score: 0) by Anonymous Coward on Saturday October 13 2018, @01:24PM (1 child)
Considering they undocumented immigrants and mentally disturbed people literally shitting in the streets. But instead of dealing with the people, they are now looking for 4 sanitation workers to go around and clean up after them.
https://www.businessinsider.com/san-francisco-poop-patrol-feces-sidewalks-housing-crisis-2018-8 [businessinsider.com]
(Score: 0) by Anonymous Coward on Saturday October 13 2018, @06:55PM
Well, it's not like they named it the "Doo-Doo Capital" [nypost.com] of the US for nothing.
(Score: 0) by Anonymous Coward on Saturday October 13 2018, @02:27PM (2 children)
(Score: 3, Insightful) by rts008 on Saturday October 13 2018, @02:50PM
Well, There seem to be a growing number of anti-vaccine people, so there is Montezuma's pool of victims for the curse.
(Score: 0) by Anonymous Coward on Saturday October 13 2018, @07:41PM
Nuclear-class hot wings.