Recently published in theBMJ:
Findings suggest that an offspring's risk of autism spectrum disorder increases following prenatal exposure to ambient pesticides within 2000 m of their mother's residence during pregnancy, compared with offspring of women from the same agricultural region without such exposure. Infant exposure could further increase risks for autism spectrum disorder with comorbid intellectual disability.
Risk of autism spectrum disorder was associated with prenatal exposure to glyphosate (odds ratio 1.16, 95% confidence interval 1.06 to 1.27), chlorpyrifos (1.13, 1.05 to 1.23), diazinon (1.11, 1.01 to 1.21), malathion (1.11, 1.01 to 1.22), avermectin (1.12, 1.04 to 1.22), and permethrin (1.10, 1.01 to 1.20).
For autism spectrum disorder with intellectual disability, estimated odds ratios were higher (by about 30%) for prenatal exposure to glyphosate (1.33, 1.05 to 1.69), chlorpyrifos (1.27, 1.04 to 1.56), diazinon (1.41, 1.15 to 1.73), permethrin (1.46, 1.20 to 1.78), methyl bromide (1.33, 1.07 to 1.64), and myclobutanil (1.32, 1.09 to 1.60); exposure in the first year of life increased the odds for the disorder with comorbid intellectual disability by up to 50% for some pesticide substances.
This story has been kicking around for over 10 years, my first recollection of it was an Italian study I read back in 2007, though this is the first time I have seen Permethrin implicated as a risk factor.
(Score: 3, Insightful) by ikanreed on Friday March 22 2019, @07:04PM (4 children)
But I'd feel a lot better if it gave an explicit mechanism.
(Score: 3, Insightful) by DeathMonkey on Friday March 22 2019, @07:29PM (2 children)
Well, at least we're starting with a correlation that actually exists this time!
(Score: 2) by ikanreed on Friday March 22 2019, @07:42PM (1 child)
At first I thought you were referring to the last debate I had on this dumbass website with a bunch of people who stuck their heads up their ass regarding some basically decent epidemiological evidence regarding marijuana's side effects, and I was so mad.
But then I realized
A. You didn't participate in that conversation
B. You're probably referring to wakefield's fraud.
And yeah, you're right. The methodology of this study is way better than the entirely imagined connection between vaccines and autism. That astonishingly obvious fact bears repeating, because we're getting deadly disease outbreaks caused by conspiracy theorists.
(Score: 2) by JoeMerchant on Saturday March 23 2019, @10:09PM
Yes, yes we are. And yes, Wakefield was wrong. On the other hand, what's the death toll so far on vaccine outbreaks that "could have been prevented" had mothers not vaccinated? Let's compare that number to 30 million (~2.5 billion births since 1998 / 83), which would be a rough estimate of the number of ASD births since Wakefield published ~20 years ago.
Repeating for the short of attention span: Wakefield was wrong - there is no direct: take an MMR shot -> increase your risk of Autism correlation ever shown.
On the other hand, we have had ~30 million ASD births since 1998, and the rate of ASD births diagnosed has roughly tripled in those 20 years, a whole other issue/debate onto itself, but let's at least agree that the ASD rate has not fallen in that timeframe.
Raise the hue and cry over vaccination, because it's something we know how to address, but, in the end, the negative results of all these mothers listening to Jenny McCarthy instead of their science based government advisers has resulted in a tiny tiny fraction of the harm to society caused by - we know not what, but it has raised the rate of ASD, across the spectrum from mild to severe, by a factor of hundreds compared to 50 years ago - and had far greater impact on society, including death rates, than the vaccination non-compliance blip.
🌻🌻 [google.com]
(Score: 1) by patricepetticoat on Friday March 22 2019, @09:11PM
There is some research about glycophosphates affecting the microbiome. I'll see if I can find it.
(Score: -1, Troll) by Anonymous Coward on Friday March 22 2019, @07:33PM (14 children)
Muh vaxines cause da autoisms.
Jes look et all da kidz wit da prolemz.
Dis' ain't da truth. Itz alls a lie!
(Score: 0) by Anonymous Coward on Friday March 22 2019, @07:44PM (6 children)
I'm not an anti-vaccer. But your inability to spell does not prove or diaprove the possibility that an ingredient in at least one vaccine may increase risk of autism.
(Score: 0) by Anonymous Coward on Friday March 22 2019, @07:51PM
Yooz lies! Stops da liein! Da vaxin mayk yu stooped!
Das wye yooz gots no anglech laikes me!
yooz needz sum drogs!
(Score: 2) by AthanasiusKircher on Friday March 22 2019, @07:59PM (2 children)
True, but your post does not prove or disprove the possibility that a teapot is circling the sun somewhere between the orbits of Earth and Mars, which is too small to be observed by telescopes.
[In case you don't get the reference, you may want to look up Bertrand Russell, and you may want to realize the burden of proof lies on a person making an assertion, not on everyone else to disprove random things.]
(Score: 1, Insightful) by Anonymous Coward on Friday March 22 2019, @08:03PM (1 child)
That's quite true. What GP's post *does* prove is that Poe's Law is in full effect. More's the pity.
(Score: 2) by aristarchus on Friday March 22 2019, @08:11PM
Shirley you meant to say, "G.E. Moore's the pity." There's just something about naive realism and Poe's Law that go together like toast and Marmite.
(Score: 1, Insightful) by Anonymous Coward on Friday March 22 2019, @08:01PM (1 child)
Clearly we need to remove the pesticides that are used in vaccines.
(Score: 1, Troll) by realDonaldTrump on Friday March 22 2019, @09:17PM
Smart idea and I've been saying that for years. You can start with the Thimeral. Keep vaccines in Refrigerator and THROW AWAY when they spoil, don't fill tiny babies with Mercury!!!!
(Score: 0) by Anonymous Coward on Friday March 22 2019, @07:44PM
vaxalones amplify pesticides.
(Score: 4, Insightful) by ikanreed on Friday March 22 2019, @07:46PM (5 children)
To be fair to the murderous psychopaths who kill children because of pseudoscience: this is only a 30% relative risk between lowest exposure and highest exposure, suggesting something besides pesticides cause the other cases.
If you get stuck on single factor mental models of cause and effect, you end up running off a cliff where you end up thinking things like taking vitamin c makes you immortal.
(Score: 2) by legont on Friday March 22 2019, @08:25PM (3 children)
There is strong evidence of connection between autism and immune system issues, which in turn may be triggered by many factors, including pesticides and immunization. On a related note, GMO are often designed to tolerate higher pesticides levels or even create pesticides naturally.
"Wealth is the relentless enemy of understanding" - John Kenneth Galbraith.
(Score: 2) by ikanreed on Friday March 22 2019, @08:49PM (1 child)
It's possible. I'll be honest, I've only read a little on the neurophysiology of autism.
(Score: 2) by JoeMerchant on Saturday March 23 2019, @10:13PM
The Italian study back about 20 years ago was finding correlations between organo-phosphate (pesticide/fertilizer) exposure and early neurodevelopment patterns similar to ASD: primarily reduced connection pruning, but other factors too.
For all the people who are so pissed at Wakefield/McCarthy followers for starting their own counter-science experiment, it's remarkable how few raise a similar cry about Monsanto filling our grocery stores with wall-to-wall products raised in Roundup.
🌻🌻 [google.com]
(Score: 0) by Anonymous Coward on Saturday March 23 2019, @11:49AM
CITATION NEEDED
(Score: 0) by Anonymous Coward on Friday March 22 2019, @10:10PM
I take large doses of vitamin C everyday and I am still alive, so it is obvious from my POV that vitamin C causes immortality.
(Score: 2, Funny) by krishnoid on Friday March 22 2019, @07:51PM (2 children)
Maybe children could be systemically presented earlier with a safe form of the pesticide, so their immune/metabolic systems would recognize it as a legitimate invasive substance and learn to reject it. Probably introduced into the bloodstream, via a series of injections or something like that.
(Score: 0) by Anonymous Coward on Friday March 22 2019, @10:20PM
No, essential oils and crystals are proven to be more effective.
(Score: 2) by JoeMerchant on Saturday March 23 2019, @10:17PM
Funny (not really, but I know you're trying.)
Pesticides, hallucinogens, etc. aren't biological agents which you develop immune responses to.
I suppose you do develop tolerance to things like opium, and require higher and higher doses to get the same high... but atypical neurodevelopment isn't like getting high on drugs, it's more like being wired to be "out there" all the time.
🌻🌻 [google.com]
(Score: 3, Funny) by realDonaldTrump on Friday March 22 2019, @08:07PM
2015, I retweeted "Too much #Monsanto in the #corn creates issues in the brain?" Now we know!!
(Score: 1, Interesting) by Anonymous Coward on Friday March 22 2019, @08:34PM (1 child)
So does this explain the rural maga republican phenomenon?
Ya ya, yer feefees are hurt, whatevs, but something makes people still support that turd and it sure as hell ain't logic and reason!
(Score: 2) by JoeMerchant on Saturday March 23 2019, @10:20PM
'round here I always thought it was the Hydrogen-Sulfide gas in the rural tap water.
https://ohsonline.com/articles/2007/10/human-health-effects-from-exposure-to-lowlevel-concentrations-of-hydrogen-sulfide.aspx [ohsonline.com]
https://www.ncbi.nlm.nih.gov/pubmed/1867221 [nih.gov]
🌻🌻 [google.com]
(Score: 0) by Anonymous Coward on Friday March 22 2019, @09:31PM
Anti-vacciners, and these clowns, two sides of the same coin.
(Score: 1) by Catalyst on Saturday March 23 2019, @04:31PM (1 child)
But I'd be a lot more comfortable with the study if it didn't call glyphosate a pesticide...
(Score: 3, Insightful) by JoeMerchant on Saturday March 23 2019, @10:23PM
It is regulated through pesticide channels:
https://www.fda.gov/food/foodborneillnesscontaminants/pesticides/ucm583713.htm [fda.gov]
and, noxious weeds are a slow moving, but insidiously expensive and damaging form of pest.
🌻🌻 [google.com]