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posted by martyb on Monday October 07 2019, @06:31PM   Printer-friendly
from the counted-on-lots-and-lots-of-fingers? dept.

Arthur T Knackerbracket has found the following story:

A research team led by Prof. Christian Eggeling from the Leibniz Institute of Photonic Technology, the Friedrich Schiller University Jena and the University of Oxford has succeeded in using high-resolution imaging to make visible how the HI virus spreads between living cells and which molecules it requires for this. Using superresolution STED fluorescence microscopy, the researchers provide direct proof for the first time that the AIDS pathogen creates a certain lipid environment for replication. "We have thus created a method for investigating how this multiplication can potentially be prevented," says Christian Eggeling. The results were published in Science Advances on October 2, 2019.

[...] They found out that only certain lipids interact with the HI virus. Although these lipids were already known in principle, the research team was able to prove this interaction directly in living and infected cells for the first time.

"This provides us with a potential target for antiviral drugs," says Christian Eggeling. "Knowing which molecules the HI virus needs in order to leave the cell and multiply is a crucial prerequisite for investigating how this can be prevented. With our technology, we can now follow this directly.“

[...] Christian Eggeling has already researched new superresolution fluorescence microscopy techniques at the Max Planck Institute for Biophysical Chemistry in Göttingen in the group of Stefan W. Hell. Together with Eric Betzig and William E. Moerner, Stefan Hell received the Nobel Prize for Chemistry in 2014. In Jena, Eggeling is now working closely with biologists and physicians to find out how these methods can be used to detect diseases earlier and more accurately and possibly even prevent them.

Reference: C. Favard, J. Chojnacki, P. Merida, N. Yandrapalli, J. Mak, C. Eggeling, D. Muriaux: HIV-1 Gag specifically restricts PI(4,5)P2 and cholesterol mobility in living cells creating a nanodomain platform for virus assembly. In: Science Advances 2019, 5. 

DOI: 10.1126/sciadv.aaw8651.


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  • (Score: -1, Offtopic) by Anonymous Coward on Monday October 07 2019, @09:26PM (1 child)

    by Anonymous Coward on Monday October 07 2019, @09:26PM (#903847)

    I thought it was well known that it was a backdoor virus.

    • (Score: -1, Flamebait) by Anonymous Coward on Monday October 07 2019, @10:07PM

      by Anonymous Coward on Monday October 07 2019, @10:07PM (#903867)

      You can also get it from straight Haitians.

  • (Score: -1, Troll) by Anonymous Coward on Monday October 07 2019, @11:19PM (2 children)

    by Anonymous Coward on Monday October 07 2019, @11:19PM (#903890)

    You can resume your regular programming

    • (Score: 0) by Anonymous Coward on Tuesday October 08 2019, @02:28AM

      by Anonymous Coward on Tuesday October 08 2019, @02:28AM (#903939)

      W.T.F.

    • (Score: 2) by esperto123 on Tuesday October 08 2019, @04:24AM

      by esperto123 (4303) on Tuesday October 08 2019, @04:24AM (#903964)

      HIV is not equal AIDS, HIV is the virus, AIDS is the syndrome.

      You can have HIV and not present the immune deficiency syndrome.

      People starting differentiating because being a carrier does not necessarily means you are going to suffer from the syndrome.

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