Parkinson's is the second most common neurodegenerative disorder after Alzheimer's disease. 500,000 individuals in the United States have been diagnosed with Parkinson's disease, and many with the disease are undiagnosed, according to the National Institute of Neurological Disorders and Stroke. Most who have Parkinson's are diagnosed after age 60. There are no drugs known to prevent the disease, but there are a growing number of treatments to relieve symptoms.
[...] The study, which enrolled 2,930 men with an average age of 76.3 when the research began, was part of the larger, population-based Osteoporotic Fractures in Men Study (MRoS), which began in 2000 and enrolled men at six medical centers nationwide. None of the participants in the subset of the MRoS cohort initially had Parkinson's, and all were living in community-based settings (i.e. not in nursing homes). Their status for many health-related factors was assessed at the start, and they were monitored through follow-up visits and questionnaires.
As part of the study, researchers monitored circadian rhythms of rest and activity over three separate 24-hour periods by having participants wear an actigraph -- a watch-like device that detects and records even slight wrist movements. The data collected from these devices were independently associated with the later development of Parkinson's.
In a previous study, Leng and Yaffe identified an association between daytime napping and the later development of Parkinson's. But the link between circadian rhythms and Parkinson's is not just a matter or disrupted sleep, according to the new study. The association held true even after accounting for indicators of sleep disturbances -- including loss of sleep; sleep inefficiency (time spent asleep after turning off the lights); leg movement during sleep; and the chronic, temporary cessation of breathing known as sleep apnea.
Journal Reference:
Yue Leng, Kristine Yaffe, Terri Blackwell, et al. Association of Circadian Abnormalities in Older Adults With an Increased Risk of Parkinson Disease, JAMA Neurology (DOI: 10.1001/jamaneurol.2020.1623)
(Score: -1, Offtopic) by Anonymous Coward on Sunday June 21 2020, @02:00PM (2 children)
A more useful study would have looked at the link between circadian abnormalities and susceptibility to COVID-19. #CoronavirusesMatter
(Score: 1) by Zinnia Zirconium on Sunday June 21 2020, @02:17PM (1 child)
College students see improved sleep with COVID-19 pandemic [upi.com]
(Score: 0) by Anonymous Coward on Sunday June 21 2020, @02:34PM
Financial Stress Now The #1 Reason Millennials Lose Sleep [thefinancialbrand.com]
Why the Covid-19 economy is particularly devastating to millennials, in 14 charts [vox.com]
(Score: 0) by Anonymous Coward on Sunday June 21 2020, @04:33PM
Sounds like just another p-hacking "research."
(Score: 2) by looorg on Sunday June 21 2020, @06:51PM (4 children)
Sleep problem might be a sign of parkinsons, so now that you cant sleep you worry about that, which potentially feeds the parkinsons. Theory confirmed.
(Score: 5, Interesting) by TheReaperD on Sunday June 21 2020, @08:58PM (3 children)
This study is 'fun' for someone like me. My circadian rhythm, or lack thereof, is so bad that I only sleep once every 2-3 days. No doctor has been able to explain or diagnose what is wrong with me in 15 years. It most closely resembles a chronic, self-producing version of neuroleptic malignant syndrome (NMS), which is not supposed to be possible. As such, there's no non-hospital treatment. This means I should ask my doctor to test for Parkinson's disease just to eliminate it as a possibility like I had them do for multiple sclerosis (MS).
Ad eundum quo nemo ante iit
(Score: 2) by sjames on Sunday June 21 2020, @09:36PM (2 children)
It couldn't hurt to check. Is this a life-long thing or a recent development (just curious).
(Score: 5, Interesting) by TheReaperD on Sunday June 21 2020, @10:17PM (1 child)
Serious symptoms started 15 years ago. But, going through my past with my doctor, we found multiple signs of it affecting me since childhood. Adults just dismissed it as 'growing pains.' Doctor confirmed my issues were very abnormal. This has since been confirmed by two more doctors. It has some similarities to fibromyalgia, but is far more severe. The pain alone is sometime enough to drop me to the ground or knock me unconscious. Lyrica and opioids only take the edge off. It would fit MS, but that has been positively eliminated both 10 years ago and again last year. Both MRI and CT scans have come up clean. I ceiling out an EEG, but anti-seizure medication has proven worthless. The only thing that has worked short term was Topamax, but I quickly became resistant within weeks and outright rejected it within two months. Not to mention, the side effects were hell (but, I would have lived with them). The only other things that have proven to help have been MDMA and Ketamine, both of which cannot be used therapeutically.
Ad eundum quo nemo ante iit
(Score: 0) by Anonymous Coward on Monday June 22 2020, @08:03PM
I'm quite sure I know what you mean, but just to be sure: this means you can't discuss them with your doctor, right?
(Score: 0) by Anonymous Coward on Monday June 22 2020, @01:22AM
https://scienceofparkinsons.com/2017/12/16/paq/#more-48745 [scienceofparkinsons.com]
(Score: 2) by jmichaelhudsondotnet on Monday June 22 2020, @05:03PM
Alarm clocks kill.
And as this is one of the core elements of industrial society, we are all owed basically everything from this system that has been killing us, our entire lives, since childhood.
Humans are not meant to wakeup to alarms. Alarm clocks kill our minds and our dreams, and us.
The machines were supposed to free us from labor, that did not pan out, the machines are enslaving us and killing us.
Anyone who cannot acknowledge this plain fact....might be a machine themselves at this point.
My counter proposal is the "chill out" clock, that awakens everyone to soothing gentle vibrations gradually.
Word is though the oligarchic dipshits behind covid are ok with basic income and a life of luxury, for themselves and their chosen slaves, they just have to thin down the population to numbers that would never have any chance of overthrowing their epsteining. While still maintaining a population of young females to prey upon at mar a lago and in ICE detention centers.