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posted by Fnord666 on Tuesday September 15 2020, @04:21PM   Printer-friendly
from the who-would-have-guessed? dept.

Sleep apnea patients at greater risk of developing COVID-19 complications, study finds:

Researchers at the University of Warwick conducted a systematic review of studies that looked at COVID-19 patients and found that those who also had sleep apnea were at a higher risk of developing serious complications and dying.

"It is likely that COVID-19 increases oxidative stress and inflammation and has effects on the bradykinin pathways, all of which are also affected in obstructive sleep apnea patients," lead author Dr. Michelle Miller said in a press release.

"When you have individuals in which these mechanisms are already affected, it wouldn't be surprising that COVID-19 affects them more strongly," she added.

[...] While there are limited studies on the link between the nasal condition and the novel coronavirus, researchers say many of the risk factors associated with sleep apnea, such as diabetes, obesity and hypertension, are similar to those associated with poorer COVID-19 outcomes.

The findings were published Monday in the journal Sleep Medicine Reviews.

[...] The study acknowledged that more research is still needed to determine whether individuals with obstructive sleep apnea should be added to the list of vulnerable groups.

"Hospitals and doctors should also be recording whether their patients have obstructive sleep apnea as a potential risk factor, and it should be included in studies and outcomes data for COVID-19. We need more data to determine whether this is something we should be more concerned about," she said.

Journal Reference:
Michelle A. Miller PhD, Francesco P. Cappuccio. A systematic review of COVID-19 and obstructive sleep apnoea, Sleep Medicine Reviews (DOI: 10.1016/j.smrv.2020.101382)


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  • (Score: 4, Insightful) by Rosco P. Coltrane on Tuesday September 15 2020, @04:23PM (12 children)

    by Rosco P. Coltrane (4757) on Tuesday September 15 2020, @04:23PM (#1051367)

    People who repeatedly stop breathing when they sleep might run into trouble if they have a disease that impairs breathing?

    Why, there's shocking news right there. Whodathunk it eh?

    • (Score: 2, Insightful) by Anonymous Coward on Tuesday September 15 2020, @04:40PM

      by Anonymous Coward on Tuesday September 15 2020, @04:40PM (#1051376)

      insight fucking ful ? Are you fucking kidding me ?

      Is that how we mod posts from fucking basement-dwelling know-it-alls who think they are smarter than the people that actually do the work nowadays ?

      This fucking site is slowly going down the /. slope.

    • (Score: 0, Troll) by Anonymous Coward on Tuesday September 15 2020, @04:52PM (8 children)

      by Anonymous Coward on Tuesday September 15 2020, @04:52PM (#1051378)

      No, this is the usual confusion over risk factors given you are already hospitalized vs in general. Obstructive sleep apnea is very common in the obese (~ 70%; https://pubmed.ncbi.nlm.nih.gov/31047125/ [nih.gov] ). Since most of the covid patients are obese, people with OSA are actually showing up less often than expected:

      Of the six studies with original data, Arentz� et al demonstrated that OSA was present in 28% of the 21 patients with coronavirus disease who presented to their intensive care unit [24]. Likewise, Bhatraju et al found that 21% of patients with severe COVID pneumonia had OSA [17]. Gupta noted that of the first twenty-one patients admitted to a hospital in India with COVID-19 one had OSA [20]. Memsoudis et al noted that of sixty ICU patients 8.3% had OSA and of the non-ICU patients 6.3% had OSA [21]. He reflected that as nearly all the patients were obese the number of expected OSA patients was low and might reflect under-diagnosis of this disease, See table 1; part (a). The Coronavirus SARS-CoV-2 and Diabetes Outcomes (CORONADO) study, aims to identify the clinical and biological features associated with risk of poor COVID-19 outcomes. In this study of people with diabetes hospitalized for COVID-19, Cariou et al reported that treated obstructive sleep apnoea was independently associated with an increased risk of death on day 7 (OR 2.80 [1.46, 5.38]) [18]. In a single case study a 74-year old male, with notable OSA, presented to hospital with hypoxia and dyspnea. He tested positive for COVID-19 but was successfully extubated and treated with average volume-assured pressure support (AVAPS) [22].

      https://www.sciencedirect.com/science/article/pii/S1087079220301258?via=ihub [sciencedirect.com]

      Intermittent oxygen deprivation is protective as seen in smokers, people living in ski communities, and asthmatics. I bet if they study frequent fliers such as pilots they will also see they are protected from severe covid.

      • (Score: 0) by Anonymous Coward on Tuesday September 15 2020, @09:00PM

        by Anonymous Coward on Tuesday September 15 2020, @09:00PM (#1051448)

        Science downvoted again on soylent. LOL, it never fails.

      • (Score: 1, Flamebait) by fakefuck39 on Wednesday September 16 2020, @03:04AM (6 children)

        by fakefuck39 (6620) on Wednesday September 16 2020, @03:04AM (#1051548)

        this is some fox news level twisting reality bs right here. no, most covid patients are not obese - being overweight does not help you catch a virus, you retard. being overweight makes covid deadlier - since you're sick already (obesity).

        smoking does not help fight covid because of oxygen deprivation, you retard. it helps because your lungs are already fighting to clear out the smoke in overdrive, so they clear covid faster, making it not spread as much or as fast. asthma is not protective from covid - it makes covid a whole lot worse. you retard.

        so yeah - a problem with breathing, such as with sleep apnea, makes a virus that is attacking your breathing organ worse. no shit, and no study needed. you absolute fucking retard.

        next up on fox - new study shows getting shot in the brain makes you dumber. well, not you - one has to be using the brain in the first place.

        • (Score: 0) by Anonymous Coward on Wednesday September 16 2020, @03:35AM (5 children)

          by Anonymous Coward on Wednesday September 16 2020, @03:35AM (#1051558)

          It says right in the OP paper that I quoted the patients were all obese. Lol. Your post goes downhill from there.

          • (Score: 1, Troll) by fakefuck39 on Wednesday September 16 2020, @06:59AM (4 children)

            by fakefuck39 (6620) on Wednesday September 16 2020, @06:59AM (#1051601)

            It quite literally does not in any way say they were all obese. You are a liar.

            • (Score: 0) by Anonymous Coward on Wednesday September 16 2020, @12:54PM (3 children)

              by Anonymous Coward on Wednesday September 16 2020, @12:54PM (#1051676)

              Check again, it says what I said. There were surprisingly few cases of OPA given the patients were mostly obese.

              Youve got severe dunning kruger bro.

              • (Score: 2) by fakefuck39 on Wednesday September 16 2020, @05:24PM (2 children)

                by fakefuck39 (6620) on Wednesday September 16 2020, @05:24PM (#1051864)

                i may got something severe, but you are completely full of crap. instead of "check again" why don't you produce the non-existent quote. and again - you are a liar. i love to dance with peg-leg sue. she's got one, and i've got two. you got none. standing must be tough. you liar.

                the question is, what kind of a retarded loser douche would lie about this, and what in the world does someone gain from that. what a loser.

                • (Score: 0) by Anonymous Coward on Thursday September 17 2020, @02:39AM (1 child)

                  by Anonymous Coward on Thursday September 17 2020, @02:39AM (#1052075)

                  Memsoudis et al noted that of sixty ICU patients 8.3% had OSA and of the non-ICU patients 6.3% had OSA [21]. He reflected that as nearly all the patients were obese the number of expected OSA patients was low and might reflect under-diagnosis of this disease, See table 1; part (a).

                  I shant respond again, it has taken you days to figure out how to read a single paragraph. Now I have narrowed it down to two sentences.

                  • (Score: 2) by fakefuck39 on Thursday September 17 2020, @03:06PM

                    by fakefuck39 (6620) on Thursday September 17 2020, @03:06PM (#1052231)

                    you should have read the whole paragraph, not two sentences. it says the literal opposite of what you claim it says. it say almost all patients were obese, and OSA patients were a small part. This means there were OSA patients who were not obese, and also means there were obese patients who were not OSA patients. When his findings did not meet his hypothesis (and your claim), he proposed a theoretical reason for why the findings are false. There is no data showing your claim true - just data showing it's false.

                    shant? yeah, you're a shant. what of it?

    • (Score: 2, Interesting) by Anonymous Coward on Tuesday September 15 2020, @05:18PM

      by Anonymous Coward on Tuesday September 15 2020, @05:18PM (#1051386)

      Being obese is a risk factor for developing sleep apnea and often times losing weight reduces the symptoms. It's not a complete causal relationship there, but obesity is a risk factor for both. It would be weird if there wasn't any carryover between the two.

    • (Score: 2, Interesting) by Runaway1956 on Tuesday September 15 2020, @05:22PM

      by Runaway1956 (2926) Subscriber Badge on Tuesday September 15 2020, @05:22PM (#1051389) Journal

      OK, I'll play along with that line of reasoning.

      Throw in the research that says the virus' original invasion vector is in the nasal passages. So, stopping breathing intermittently likely gives the virus more time to work within the nasal passages. That kinda goes along with the idea that healthy people wearing a mask forces them to re-breathe viruses, thus giving viruses more time to work within the nasal passages.

      I'm forced to agree with the "more research needed" bit.

  • (Score: -1, Offtopic) by Anonymous Coward on Tuesday September 15 2020, @05:12PM

    by Anonymous Coward on Tuesday September 15 2020, @05:12PM (#1051382)

    They need to get on a paper on how internet hacking attempts require computer fans to spin up, impacting the airborne transmission of Covid-19.
    "Israeli researchers discover link between Internet and Covid-19!"

  • (Score: 0) by Anonymous Coward on Tuesday September 15 2020, @06:46PM (5 children)

    by Anonymous Coward on Tuesday September 15 2020, @06:46PM (#1051417)

    CPAP machines (ventilators used to treat sleep apnea) increase your risk of pneumonia.

    • (Score: 1, Redundant) by fakefuck39 on Wednesday September 16 2020, @03:11AM (4 children)

      by fakefuck39 (6620) on Wednesday September 16 2020, @03:11AM (#1051550)

      a CPAP is not a ventilator. that's like saying jacking off is the same as shoving your hand up the urethra.. you sleep comfortably in a CPAP. you usually have to be knocked unconscious to use a ventilator.

      a CPAP does not increase your risk of pneumonia. if your CPAP is dirty with bacteria, you'll get that blown into your lungs by the CPAP and get pneumonia. the CPAP does not cause it. that's like saying "band-aids increase risk of infection." They do, if you dip the band-aid in the toilet first.

      • (Score: 1, Touché) by Anonymous Coward on Wednesday September 16 2020, @01:56PM (3 children)

        by Anonymous Coward on Wednesday September 16 2020, @01:56PM (#1051712)

        It's not a ventilator, just a respiratory ventilation device!

        It doesn't increase the risk of pneumonia if they're perfectly sterile, just in the way people actually use them!

        Wow you're really fucking smart and added a lot to this conversation, thanks for your input.

        • (Score: 2) by fakefuck39 on Wednesday September 16 2020, @05:31PM (2 children)

          by fakefuck39 (6620) on Wednesday September 16 2020, @05:31PM (#1051870)

          correct. a CPAP is not a ventilator. medical terms have meanings, and CPAP and a ventilator are completely different devices. a ventilator is not something you can even use by yourself, since they have to sedate you to put you on one. you should look up what a ventilator is and learn something.

          i'm not that smart. the question is, how dumb to you have to be to not know what a ventilator is, and how dumb do you have to be to double down that a CPAP is a ventilator, when a 5 second google search will tell you it's not. it's like a kid with a diaper full of shit yelling it smells bad. all you're doing is making more people notice you need a diaper change. fucking clown.

          • (Score: 0) by Anonymous Coward on Wednesday September 16 2020, @07:04PM (1 child)

            by Anonymous Coward on Wednesday September 16 2020, @07:04PM (#1051929)

            https://en.wikipedia.org/wiki/Modes_of_mechanical_ventilation#Continuous_positive_airway_pressure [wikipedia.org]

            Here's your five second Google search.

            It's almost like there are different types of ventilators, and you're only describing a specific class, like invasive ventilators, or something.

            i'm not that smart.

            Broken clock, it's your time to shine.

            • (Score: 2) by fakefuck39 on Thursday September 17 2020, @03:12PM

              by fakefuck39 (6620) on Thursday September 17 2020, @03:12PM (#1052235)

              so you don't know the difference between "mechanical ventilation" and "ventilator?" tell me, do you know the difference between a construction truck and a sports car - both modes of transportation. that doesn't make a truck a sports car. is english a second language? take an esl class at a community college - it'll help.

              it's amazing in your five second google search you ignored literally every single result, since they all say a cpap is not a ventilator. here you go, first result. but you can pick any other one on the first page of results.

              https://aeroflowinc.com/need-ventilator-instead-bipap-cpap/ [aeroflowinc.com]

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