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posted by Fnord666 on Monday May 03, @06:58AM   Printer-friendly [Skip to comment(s)]
from the What's-on-your-plate? dept.

Dietary Therapy for Cancer? Amino Acid Consumption Determines the Fate of Cancer Cells:

A tumor is a group of cancer cells that multiplies—or proliferates—uncontrollably. Tumors originate from single cells that become cancerous when genes that cause cells to proliferate are over-activated. However, because these genes, called oncogenes, often also cause cell death, activation of a single oncogene within a cell is not enough for it to become a cancer cell. [...] For a cell to slip through the cracks and become cancer, several other oncogenes, along with cancer-suppressing genes, need to be activated in a multi-step process. The details of this process were the topic of the new study.

The international research group led by Sa Kan Yoo at RIKEN BDR focused on the oncogene Src and investigated how cell proliferation—oncogenesis—and cell death are regulated in the fruit fly. They showed that Src does not induce cell death as a result of cell proliferation, but instead drives both processes independently and simultaneously. [...] "Our major finding was that the oncogene Src promotes cell death and cell proliferation via parallel pathways."

[...] "We were excited to find that manipulating the amount of dietary methionine can affect cell proliferation but not cell death," says Yoo. "Currently we don't know whether our finding in flies will translate to cases of human cancer. But, we speculate that it will in particular cases because some human cancers also activate the Src gene.

[...] Since the process of oncogenesis is known to be the same in both fruit flies and mammals, the new findings can help explain how human cancers develop.

Journal Reference:
Hiroshi Nishida, Morihiro Okada, Lynna Yang, et al. Methionine restriction breaks obligatory coupling of cell proliferation and death by an oncogene Src in Drosophila, (DOI: 10.7554/eLife.59809)


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  • (Score: -1, Troll) by Anonymous Coward on Monday May 03, @12:21PM

    by Anonymous Coward on Monday May 03, @12:21PM (#1145640)

    funk you eds

  • (Score: 3, Informative) by pdfernhout on Monday May 03, @01:12PM (5 children)

    by pdfernhout (5984) on Monday May 03, @01:12PM (#1145650) Homepage

    https://www.drfuhrman.com/health-concerns/26/cancer [drfuhrman.com]
    "Cancer is the abnormal growth of cells that results in tumors that can spread to different areas of the body. Diet and lifestyle play a major role in the prevention and improvement of various cancers, including breast, prostate, colorectal, and skin cancers. A diet focused on immune-boosting foods, especially G-BOMBS (greens, beans, onions, mushrooms, berries, seeds/nuts) is crucial in the fight against cancer."

    https://www.drfuhrman.com/blog/62/the-healthiest-anti-cancer-foods-g-bombs [drfuhrman.com]
    "”G-BOMBS” is an acronym that you can use to remember the best anti-cancer, health-promoting foods on the planet. These are the foods that you should eat every day, making up a significant proportion of your diet. They are extremely effective at preventing chronic disease, including cancer and promoting health and longevity.
    * Greens
    * Beans
    * Onions
    * Mushrooms
    * Berries
    * Seeds"

    Excellent nutrition can help reverse heart disease and diabetes too:

    "The End of Heart Disease: The Eat to Live Plan to Prevent and Reverse Heart Disease"
    https://www.amazon.com/gp/product/0062249363/ [amazon.com]

    "The End of Diabetes: The Eat to Live Plan to Prevent and Reverse Diabetes"
    https://www.amazon.com/End-Diabetes-Live-Prevent-Reverse-ebook/dp/B0089LOG7U/ [amazon.com]

    --
    The biggest challenge of the 21st century: the irony of technologies of abundance used by scarcity-minded people.
    • (Score: 3, Insightful) by number11 on Monday May 03, @04:04PM

      by number11 (1170) on Monday May 03, @04:04PM (#1145705)

      A "celebrity doctor" [wikipedia.org] who peddles vitamins, foods, and books. Who coins terms like "G-B0MB" and "Nutritarian". Whose name is a registered trademark. Well, maybe, but I tend to assume those people are quacks. I'd want to see this backed up by reputable sources first.

    • (Score: 1, Interesting) by Anonymous Coward on Monday May 03, @04:30PM (3 children)

      by Anonymous Coward on Monday May 03, @04:30PM (#1145712)

      My diet is pretty close to that already, mushrooms and onions are not every day, but the rest are nearly daily. A cup of whole grains (granola/muesli) to keep the plumbing working. Most days there is one serving of meat/foul/fish, with one or two vege days/week.

      • (Score: 0) by Anonymous Coward on Monday May 03, @04:34PM (1 child)

        by Anonymous Coward on Monday May 03, @04:34PM (#1145715)

        Virtue signaled, thank you.

        • (Score: 0) by Anonymous Coward on Monday May 03, @05:24PM

          by Anonymous Coward on Monday May 03, @05:24PM (#1145730)

          From https://effectiviology.com/virtue-signaling/ [effectiviology.com]
          > Virtue signaling is the act of speaking or behaving in a way that’s meant to demonstrate one’s good moral values.

          I don't get the connection between moral values and health/aging outcomes?
          Be happy if the granola eating AC stays healthy--they will (on aggregate) reduce your health insurance costs.

      • (Score: 3, Touché) by ChrisMaple on Tuesday May 04, @02:13AM

        by ChrisMaple (6964) on Tuesday May 04, @02:13AM (#1145918)

        How's that diet of "foul" working for you?

  • (Score: 0) by Anonymous Coward on Monday May 03, @03:52PM (1 child)

    by Anonymous Coward on Monday May 03, @03:52PM (#1145700)

    Anyone ever notice that "diet" is touted by those with commercial interests as a possible solution to all and every problem. What a coincidence! You can direct sell dietary supplements to witless sufferers and give them the feeling they are taking control and learning something. Whereas all they're doing is buying MOAR cookies with some bullshit additive that makes them taste worse than regular cookies but cost twice as much.

    Just buy the Oreos and get the sugar rush/crash experience without the high drama of battling cancer or saving humanity or whatever.

    • (Score: 2) by Reziac on Tuesday May 04, @04:15AM

      by Reziac (2489) on Tuesday May 04, @04:15AM (#1145975) Homepage

      Some types of cancer feed on glucose, and can be at least partially controlled by going strictly carb-free. But for the most part, you're right, it's a hopeful correlation rather than a proper treatment, and quite an astonishing markup on supplements that are exceedingly cheap to produce.

  • (Score: 2) by ChrisMaple on Tuesday May 04, @02:20AM (1 child)

    by ChrisMaple (6964) on Tuesday May 04, @02:20AM (#1145924)

    Four paragraphs of summary and the only important conclusion, that methionine might be bad for you, isn't mentioned.

    • (Score: 2) by Reziac on Tuesday May 04, @04:19AM

      by Reziac (2489) on Tuesday May 04, @04:19AM (#1145978) Homepage

      Which would be a silly conclusion, since methionine is an essential amino acid. You can't live without it.

      https://en.wikipedia.org/wiki/Methionine [wikipedia.org]
      https://pubchem.ncbi.nlm.nih.gov/compound/methionine [nih.gov]

      "Methionine is one of nine essential amino acids in humans (provided by food), Methionine is required for growth and tissue repair. A sulphur-containing amino acid, methionine improves the tone and pliability of skin, hair, and strengthens nails. Involved in many detoxifying processes, sulphur provided by methionine protects cells from pollutants, slows cell aging, and is essential for absorption and bio-availability of selenium and zinc. Methionine chelates heavy metals, such as lead and mercury, aiding their excretion. It also acts as a lipotropic agent and prevents excess fat buildup in the liver."

      "Animals fed the deficient diet for two weeks lost (29%) weight and after five weeks weighed one third as much as those on the sufficient diet, and also developed anemia (P 0.01). Hepatic transaminases progressively increased from two to five weeks (P 0.01), leading to severe hepatic pathology." (obviously you can't ethically do this experiment on humans.)

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