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posted by chromas on Sunday August 01 2021, @09:50AM   Printer-friendly
from the antiantioxidants dept.

Research Shows Cell Aging Can Be Slowed by Oxidants:

At high concentrations, reactive oxygen species — known as oxidants — are harmful to cells in all organisms and have been linked to aging. But a study from Chalmers University of Technology, Sweden, has now shown that low levels of the oxidant hydrogen peroxide can stimulate an enzyme that helps slow down the aging of yeast cells.

One benefit of antioxidants, such as vitamins C and E, is that they neutralize reactive oxygen species — known as oxidants — which may otherwise react with important molecules in the body and destroy their biological functions. Larger amounts of oxidants can cause serious damage to DNA, cell membranes, and proteins for example. Our cells have therefore developed powerful defense mechanisms to get rid of these oxidants, which are formed in our normal metabolism.

It was previously believed that oxidants were only harmful, but recently we have begun to understand that they also have positive functions. Now, the new research from Chalmers University of Technology shows that the well-known oxidant hydrogen peroxide can actually slow down the aging of yeast cells. Hydrogen peroxide is a chemical used for hair and tooth whitening, among other things. It is also one of the oxidants formed in our metabolism that is harmful at higher concentrations.

The Chalmers researchers studied the enzyme Tsa1, which is part of a group of antioxidants called peroxiredoxins.

“Previous studies of these enzymes have shown that they participate in yeast cells’ defenses against harmful oxidants,” says Mikael Molin, who leads the research group at Chalmers’ Department of Biology and Biological Engineering. “But the peroxiredoxins also help extend the life span of cells when they are subjected to calorie restriction. The mechanisms behind these functions have not yet been fully understood.”

Journal Reference:
Friederike Roger, Cecilia Picazo, Wolfgang Reiter, et al. Peroxiredoxin promotes longevity and H2O2-resistance in yeast through redox-modulation of protein kinase A, eLife (DOI: 10.7554/eLife.60346)


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  • (Score: 0) by Anonymous Coward on Sunday August 01 2021, @10:10AM

    by Anonymous Coward on Sunday August 01 2021, @10:10AM (#1161923)

    You can accelerate it by drinking whikey, bottles and bottles of them.

    And it's worth it.

    Ugh, yeah. KInda. Maybe.

  • (Score: 2, Informative) by Anonymous Coward on Sunday August 01 2021, @10:36AM (2 children)

    by Anonymous Coward on Sunday August 01 2021, @10:36AM (#1161927)

    Vaccination. Just do it.

    • (Score: -1, Troll) by Anonymous Coward on Sunday August 01 2021, @11:01AM (1 child)

      by Anonymous Coward on Sunday August 01 2021, @11:01AM (#1161932)

      Which one?

      • (Score: 1, Offtopic) by HiThere on Sunday August 01 2021, @02:52PM

        by HiThere (866) Subscriber Badge on Sunday August 01 2021, @02:52PM (#1161963) Journal

        Well, smallpox vaccine isn't useful in most places.

        --
        Javascript is what you use to allow unknown third parties to run software you have no idea about on your computer.
  • (Score: 3, Insightful) by Beryllium Sphere (r) on Sunday August 01 2021, @04:04PM (1 child)

    by Beryllium Sphere (r) (5062) on Sunday August 01 2021, @04:04PM (#1161970)

    This is a good illustration of the principle set forth by my friend who likes to say "biology is messy".

    • (Score: 0) by Anonymous Coward on Monday August 02 2021, @03:22PM

      by Anonymous Coward on Monday August 02 2021, @03:22PM (#1162262)

      I remember reading a thread either here or on the green site that was talking about how life would be constrained to the outer parts of the galaxy.
      Person 1: There is too much Cosmic Radiation in the inner parts of the galaxy, it would rip DNA apart and so life cannot exist so close to the galactic center
      Person 2: It seems that any life that evolved there would have, by necessity, evolved some sort of protection from this, likely in the form of faster DNA repair
      Person 3: Follow that logic a bit further and you will realize that any life that evolved that close the the galactic center would not only be tolerant of the cosmic radiation, but dependent on it

  • (Score: 0) by Anonymous Coward on Tuesday August 03 2021, @08:38PM

    by Anonymous Coward on Tuesday August 03 2021, @08:38PM (#1162833)

    Naturally occurring ozone is good for many reasons. If you keep your windows and doors closed the ozone in your house gets depleted and this is bad for a variety of reasons. You want to ventilate your house regularly to replenish the outside ozone as the oxidative effects are good.

    The great big ozone video
    bigclivedotcom
    https://youtu.be/1ymcJ9qKC7I [youtu.be]

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