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posted by janrinok on Monday September 13, @09:03PM   Printer-friendly [Skip to comment(s)]

TAU Team Reverses Early Signs of Alzheimer's:

Approximately 50 million people worldwide live with Alzheimer's or other related forms of dementia. Alzheimer's disease leads to memory loss and impairment in cognitive function, and is the most common cause of dementia among older adults. While certain treatments can help reduce symptoms and sometimes reduce disease progression, there is currently no way to prevent or cure Alzheimer's.

[...] Using hyperbaric oxygen therapy (HBOT), in which subjects breathe 100% oxygen in a special chamber of high atmospheric pressure, the researchers were able to reverse brain damages associated with the biological hallmarks of Alzheimer's.

"By treating the root problem that causes cognitive deterioration with age, we are in fact mapping out the way to prevention," says co-lead researcher Prof. Shai Efrati.

[...] "After a series of hyperbaric treatments, elderly patients who were already suffering from memory loss showed an improvement of blood flow to the brain as well as a real improvement in cognitive performance," said co-lead investigator Prof. Uri Ashery.


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  • (Score: 0) by Anonymous Coward on Monday September 13, @09:11PM (1 child)

    by Anonymous Coward on Monday September 13, @09:11PM (#1177502)

    I sure hope these results are more than just wishful thinking. Unfortunately, many populations have shown "improvements" in a wide variety of metrics...because the experimental subjects were stimulated by participating in the experiment.

    Get people with early stage memory loss engaged in something (almost anything) and frequently they get a little better.

    • (Score: 2) by rigrig on Tuesday September 14, @07:16AM

      by rigrig (5129) Subscriber Badge <soylentnews@tubul.net> on Tuesday September 14, @07:16AM (#1177633) Homepage

      Yeah, looking at the paper [researchgate.net]:

      The protocol comprised of 60 daily sessions, 5 sessions per week within a three month period. Each session included breathing 100% oxygen by mask at 2ATA for 90 minutes with 5-minute air breaks every 20 minutes. Compression/ decompression rates were 1 meter/minute. The control arm received no active intervention as a no-contact group.

      I'd feel a lot happier about this if the control group had (instead of no treatment) received similar sessions, only using just regular air instead of the 100% oxygen.

      --
      No one remembers the singer.
  • (Score: -1, Offtopic) by Mockingbird on Monday September 13, @09:30PM (3 children)

    by Mockingbird (15239) on Monday September 13, @09:30PM (#1177509)

    Wasn't this hyperbaric stuff just hyped a while ago as the cure for COVID-19? The hyperbole is certainly hilarious, but they forgot the zinc!

    --
    "It is a sin to kill a mockingbird" Atticus Finch
  • (Score: 4, Funny) by DannyB on Monday September 13, @09:40PM (5 children)

    by DannyB (5839) Subscriber Badge on Monday September 13, @09:40PM (#1177512) Journal

    There was another cure for Alzheimers, but I can't seem to remember what it was.

    --
    Never use a needlessly simple solution to a problem when a much more complex solution would suffice.
    • (Score: -1, Troll) by Anonymous Coward on Monday September 13, @09:59PM (3 children)

      by Anonymous Coward on Monday September 13, @09:59PM (#1177513)

      A baseball bat to the head... sounds like you could use a round of treatment. I'm sure we can find plenty of volunteers if your insurance doesn't cover it.

    • (Score: 2) by corey on Monday September 13, @11:25PM

      by corey (2202) on Monday September 13, @11:25PM (#1177537)

      :)

      I was thinking of ways to oxygenate the brain without access to a hyperbaric chamber. Getting out and going hiking? Doing daily cardio workouts out in nature? And pranayama yoga breathing exercises (I’ve done this a bit). I guess you’d need to be diagnosed first.

  • (Score: 0) by Anonymous Coward on Monday September 13, @10:25PM (9 children)

    by Anonymous Coward on Monday September 13, @10:25PM (#1177518)

    So, our resident faux philosopher should have started this about 2300 years ago?

    • (Score: 0) by Anonymous Coward on Monday September 13, @11:23PM (8 children)

      by Anonymous Coward on Monday September 13, @11:23PM (#1177536)

      He'd be just breathing faster, get more oxygen. Hyperventilating is the medical term, yes.

      • (Score: 4, Funny) by aristarchus on Monday September 13, @11:28PM (7 children)

        by aristarchus (2645) on Monday September 13, @11:28PM (#1177538) Journal

        Do you think that's air you're breathing?

        --
        FatPhil: "F**k me, ran out of all of today's modpoints in just 10 minutes. "
        • (Score: 0) by Anonymous Coward on Tuesday September 14, @12:33AM (6 children)

          by Anonymous Coward on Tuesday September 14, @12:33AM (#1177553)

          Is your question in any relation with the topic? Epistemological, ontological, deontological, gerontological, whatever, any kind of relation?

          • (Score: 2) by aristarchus on Tuesday September 14, @12:40AM (5 children)

            by aristarchus (2645) on Tuesday September 14, @12:40AM (#1177556) Journal

            Presumptions that oxygenation is the operative mechanism to the alleged treatment for Old Timer's Disease. Pseudo-science on SN again. And, we could be in the Matrix, gacking down the horse de-wormer.

            --
            FatPhil: "F**k me, ran out of all of today's modpoints in just 10 minutes. "
            • (Score: 5, Informative) by c0lo on Tuesday September 14, @01:30AM (4 children)

              by c0lo (156) Subscriber Badge on Tuesday September 14, @01:30AM (#1177571) Journal

              Presumptions that oxygenation is the operative mechanism to the alleged treatment for Old Timer's Disease. Pseudo-science on SN again.

              Ummm... at the end of TFA:

              The Tel Aviv University team that led the study included Prof. Shai Efrati of the Sackler Faculty of Medicine and the Sagol School of Neuroscience, Prof. Uri Ashery and Dr. Pablo Blinder of the The George S. Wise Faculty of Life Sciences and the Sagol School of Neuroscience, and Dr. Ronit Shapira and Dr. Amir Hadanny. They are all affiliated with the Shamir Medical Center. The findings were published in the journal Aging.

              Some Googling after the name of the authors and asking for a DOI, I got this [nih.gov]. They declared they used "two-photon live animal imaging, behavioral tasks, and biochemical and histological analysis" on model mice, and found "HBOT reduced amyloid burden by reducing the volume of pre-existing plaques and attenuating the formation of new ones". They tabled the hypothesis of "changes in amyloid precursor protein processing, elevated degradation and clearance of Aß protein" as a possible mechanism that could offer an explanation.

              And here's the DOI [doi.org]

              ---

              With all the information now at hand, feel free to contact the authors and communicate your peer review on their methods and findings, I'm sure they'll see your points.

              --
              https://www.youtube.com/watch?v=aoFiw2jMy-0
              • (Score: 2) by aristarchus on Tuesday September 14, @06:11AM (3 children)

                by aristarchus (2645) on Tuesday September 14, @06:11AM (#1177622) Journal

                Um, c0lo, I think many have interpreted your comment contrary as to what you intended? Can't be helped, quite often, on SoylentNews, where STEM and science and logic and evidence and facts and stuff, are important.

                --
                FatPhil: "F**k me, ran out of all of today's modpoints in just 10 minutes. "
                • (Score: 2) by c0lo on Tuesday September 14, @06:25AM (2 children)

                  by c0lo (156) Subscriber Badge on Tuesday September 14, @06:25AM (#1177625) Journal

                  Um, c0lo, I think many have interpreted your comment contrary as to what you intended?

                  To their peril. I stopped feeling responsible for my humanoid brothers' shortfalls and longfails, I barely have enough of my lifetime to dedicate to making my own mistakes (God, they're delicious).

                  --
                  https://www.youtube.com/watch?v=aoFiw2jMy-0
                  • (Score: 2) by aristarchus on Tuesday September 14, @06:46AM (1 child)

                    by aristarchus (2645) on Tuesday September 14, @06:46AM (#1177626) Journal

                    Jdi v míru, můj bratře.

                    --
                    FatPhil: "F**k me, ran out of all of today's modpoints in just 10 minutes. "
                    • (Score: 2) by c0lo on Tuesday September 14, @06:51AM

                      by c0lo (156) Subscriber Badge on Tuesday September 14, @06:51AM (#1177627) Journal

                      Köszönöm (I hope google translate works fine for something that simple).

                      --
                      https://www.youtube.com/watch?v=aoFiw2jMy-0
  • (Score: 3, Interesting) by Beryllium Sphere (r) on Tuesday September 14, @05:10AM

    by Beryllium Sphere (r) (5062) on Tuesday September 14, @05:10AM (#1177615)

    which makes sense since Google prioritizes recent things, but I thought I had read about work on hyperbaric oxygen for treating dementia from decades ago.

  • (Score: 2) by gawdonblue on Tuesday September 14, @07:51AM (1 child)

    by gawdonblue (412) on Tuesday September 14, @07:51AM (#1177637)

    Didn't know what "TAU" stood for so I looked it up: "An alien race from the fictional Warhammer 40,000 universe".

    The humanitarian work of alien races never ceases to amaze!

    • (Score: 3, Touché) by PiMuNu on Tuesday September 14, @12:18PM

      by PiMuNu (3823) on Tuesday September 14, @12:18PM (#1177668)

      Also a greek letter. Hope they don't get shot down for trademark infringement.

  • (Score: 0) by Anonymous Coward on Tuesday September 14, @05:57PM

    by Anonymous Coward on Tuesday September 14, @05:57PM (#1177777)

    They don't breath pure oxygen but it is certainly at high pressure, some effects should carry over.

  • (Score: 0) by Anonymous Coward on Thursday September 16, @01:28PM

    by Anonymous Coward on Thursday September 16, @01:28PM (#1178256)

    So could increased atmospheric CO2 levels contribute to Alzheimer's?

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