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posted by martyb on Tuesday September 14, @09:46PM   Printer-friendly [Skip to comment(s)]
from the worth-a-shot dept.

Ebola vaccine regimen generates strong immune response in children and adults in a clinical trial in Sierra Leone:

Results support the use of Johnson & Johnson's vaccine regimen for Ebola virus disease prevention

Johnson & Johnson's two-dose Ebola vaccine regimen is safe, well tolerated and produces a strong immune response in people over the age of one, according to two new papers published in The Lancet Infectious Diseases.

The EBOVAC-Salone study provides important further evidence for the potential of the regimen using the Ad26.ZEBOV and MVA-BN-Filo vaccines to be used as a protective measure against Ebola virus disease for both children and adults.

Conducted in Sierra Leone, the study is the first to assess the safety and tolerability of this vaccine regimen in a region affected by the 2014-2016 West African Ebola outbreak, which was the worst on record. It is also the first study reporting the evaluation of this vaccine regimen in children.

[...] The authors found that the vaccine regimen was well tolerated and induced antibody responses to Zaire ebolavirus 21 days after the second dose in 98% of participants, with the immune responses persisting in adults for at least two years.

During the 2014-16 outbreak of Ebola in West Africa, 28,652 cases and 11,325 deaths from Ebola were reported. Approximately 20% of cases were in children under 15 years, and children younger than five years are at a higher risk of death than adults.

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  • (Score: 5, Funny) by Anonymous Coward on Tuesday September 14, @09:50PM (17 children)

    by Anonymous Coward on Tuesday September 14, @09:50PM (#1177870)

    Keep your damn untested ebola vaccine away from me! I ain't hurtin' anyone not taking your magnetizing Gates serum. Besides, there is no ebola. That's just something they tell the Africans to keep them scared. And if there was ebola, it wouldn't be any worse than the flu.

    • (Score: 5, Interesting) by Opportunist on Tuesday September 14, @10:25PM (15 children)

      by Opportunist (5545) on Tuesday September 14, @10:25PM (#1177880)

      You know, I wonder if the Africans are stupid like that, too, or whether they know, probably from first hand experience, that ebola is a killer and thus would walk a few days to get vaccinated.

      • (Score: 2, Interesting) by Anonymous Coward on Tuesday September 14, @10:36PM (2 children)

        by Anonymous Coward on Tuesday September 14, @10:36PM (#1177881)

        Sub-saharan Africa has a long history with pretty much every disease imaginable. Lock-downs and mandatory quarantines have been normal and accepted since time immemorial. The biggest problem they face is that they now have large cities where those methods are less effective so they need to vaccinate, but there are militant anti-vax groups like Boko Haram running around killing people over it.

        • (Score: 1, Touché) by Anonymous Coward on Wednesday September 15, @03:27AM (1 child)

          by Anonymous Coward on Wednesday September 15, @03:27AM (#1177957)

          Boko Haram just want freedom from the pedophile pizza-loving elite like we all do.

          • (Score: 0) by Anonymous Coward on Wednesday September 15, @10:27PM

            by Anonymous Coward on Wednesday September 15, @10:27PM (#1178135)

            True. They want to replace them with pedophile falafel-loving elite. Look up what happens to the girls they 'liberate' from the schools they raid.

      • (Score: -1, Redundant) by Anonymous Coward on Tuesday September 14, @11:53PM (6 children)

        by Anonymous Coward on Tuesday September 14, @11:53PM (#1177897)

        Africans are stupid, but since they're Muslims they'll do whatever their imams tell them to. So all you need us a religious scholar to point out how much Mohammad loved vaccines and you'll have no problems getting 100% compliance since the alternative would likely be public beheading.

        • (Score: 3, Informative) by tizan on Wednesday September 15, @12:45AM (4 children)

          by tizan (3245) on Wednesday September 15, @12:45AM (#1177909)

          Wow....your knowledge of Africa as a continent is very limited...Foxitis school of social studies is it ?

          https://en.wikipedia.org/wiki/Islam_in_Africa [wikipedia.org]

          You'll realize that on top of that islam has different flavors as christianity has ...you know like you can't equate a mormon to a catholic or Lutheran or 7th day adventist.

          Social media is a terrible thing....ignorants are given louder voices than the learned !

          • (Score: 0, Touché) by Anonymous Coward on Wednesday September 15, @06:44AM

            by Anonymous Coward on Wednesday September 15, @06:44AM (#1177964)

            You'll realize that on top of that islam has different flavors as christianity has ...you know like you can't equate a mormon to a catholic or Lutheran or 7th day adventist.

            I can equate all of them, including the moslems. They are all delusional believers in an irrational fictional sky fairy.

          • (Score: 0) by Anonymous Coward on Wednesday September 15, @11:24PM (2 children)

            by Anonymous Coward on Wednesday September 15, @11:24PM (#1178144)

            Thank you for coming to the support of Boko Haram. For some strange reason they keep getting bad press round my way, it's refreshing to see someone stick up for them and their progressive social policies.

            • (Score: 0) by Anonymous Coward on Thursday September 16, @05:32AM

              by Anonymous Coward on Thursday September 16, @05:32AM (#1178196)

              Africa is huge, Boko Haram is not. They are only active in a small area, and it's almost all economically motivated.

            • (Score: 2) by tizan on Friday September 17, @05:02PM

              by tizan (3245) on Friday September 17, @05:02PM (#1178705)

              Yes just like all Americans (North, south and central) are part of the Sect of Fundamentalist Church of Jesus Christ of Latter day Saints.

        • (Score: 0) by Anonymous Coward on Wednesday September 15, @01:22AM

          by Anonymous Coward on Wednesday September 15, @01:22AM (#1177924)

          I find your analysis fascinating and brilliant. We should get the Christian imams and mullahs in the USA to promote vaccines as well.

      • (Score: 4, Informative) by Beryllium Sphere (r) on Wednesday September 15, @12:55AM (1 child)

        by Beryllium Sphere (r) (5062) on Wednesday September 15, @12:55AM (#1177912)
        • (Score: 3, Interesting) by Opportunist on Thursday September 16, @08:02AM

          by Opportunist (5545) on Thursday September 16, @08:02AM (#1178228)

          Kinda weird at first glance, those that could easily and freely get it don't want it, those that have to take insane hardships upon themselves to have a chance to maybe get it will do so.

          Is it true that we value only that which we can't get easily? It's almost like with education, you'll notice that often you find people who have a hard time getting reliable information will dig through a mountain of propaganda just to get a nugget of truth while people who get it dumped upon them will dig long and hard to make sure they can ignore it and instead believe some harebrained truther bullshit.

      • (Score: 5, Informative) by Thexalon on Wednesday September 15, @02:55AM (1 child)

        by Thexalon (636) on Wednesday September 15, @02:55AM (#1177955)

        African countries have been, on average, far better at dealing with Covid than the US, Italy, the UK, and many other countries with far more resources [jhu.edu]. I have to think that direct experience of Ebola, AIDS, malaria, and other serious and deadly diseases has an effect on how seriously they take the threat and how willing the citizens are to take precautions.

        --
        The inverse of "I told you so" is "Nobody could have predicted"
        • (Score: 1, Interesting) by Anonymous Coward on Thursday September 16, @05:31AM

          by Anonymous Coward on Thursday September 16, @05:31AM (#1178195)

          They do seem to be taking it seriously, and they have been doing better in some ways, but keep in mind that not every death gets recorded in many poor countries, let alone cause of death, so those numbers are probably low. They still have a critical need for vaccines as well since they are later in the queue that first world countries, and production has not kept up with demand.

      • (Score: -1, Troll) by Anonymous Coward on Wednesday September 15, @12:14PM

        by Anonymous Coward on Wednesday September 15, @12:14PM (#1177967)

        Ebola and Marburg frighten me, but Africans have lived with them without vaccines for a long time. Meanwhile, they have had large cities, and less-than-perfect healthcare systems and regimens. So if those diseases were a dire threat to civilization, then presumably they would have wiped out Africans a long time ago.

        Sleeping sickness and Malaria and AIDS kill less quickly, however, and have presented a more widespread, longer term threat to that continent.

    • (Score: 3, Informative) by DeathMonkey on Wednesday September 15, @05:57PM

      by DeathMonkey (1380) on Wednesday September 15, @05:57PM (#1178064) Journal

      I ain't hurtin' anyone not taking your magnetizing Gates serum

      Shh....just don't let them know we're actually putting the chips in the Ivermectin!

      Bill and Melinda Gates Fund Global Ivermectin & Fluvoxamine Clinical Trial Targeting COVID-19: Together COVID-19 Trial [trialsitenews.com]
      To advance understanding of pharmacology of ivermectin and to enhance treatment of malaria [gatesfoundation.org]

  • (Score: -1, Spam) by Anonymous Coward on Tuesday September 14, @10:45PM

    by Anonymous Coward on Tuesday September 14, @10:45PM (#1177885)

    "You should go to a rodeo sometime." Eric lectured Sally. Sally was not programmed by the rope or hose, but she knew full well what Eric was talking about when he grabbed that hammer.

    Soup coming to a boil.

    The hairy beast paused to urinate in the forest, having eluded capture by the humans. With his dirt encrusted fingernails he carved out a circle on his forehead, and a small sparrow flew out flooding the beast with copious dopamine.

    Give the bird a tail.

  • (Score: -1, Spam) by Anonymous Coward on Tuesday September 14, @10:58PM

    by Anonymous Coward on Tuesday September 14, @10:58PM (#1177890)

    "You've breathed your last!" cried the penis. "I'll not enter your establishment ever again." The Lonely Vagina Hotel would never see Mr. Penis enter again, except by way of a BACK DOOR.

    Mystery meat.

    The humming coming from the overworked pickle formed a peculiar shape as it exhaled a day's worth of soup now brought to steam.

    Slime is real.

  • (Score: -1, Spam) by Anonymous Coward on Wednesday September 15, @12:06AM (1 child)

    by Anonymous Coward on Wednesday September 15, @12:06AM (#1177899)

    "You should go to a rodeo sometime." Eric lectured Sally. Sally was not programmed by the rope or hose, but she knew full well what Eric was talking about when he grabbed that hammer.

    Soup coming to a boil.

    The hairy beast paused to urinate in the forest, having eluded capture by the humans. With his dirt encrusted fingernails he carved out a circle on his forehead, and a small sparrow flew out flooding the beast with copious dopamine.

    Give the bird a tail?

    • (Score: -1, Spam) by Anonymous Coward on Wednesday September 15, @12:12AM

      by Anonymous Coward on Wednesday September 15, @12:12AM (#1177900)

      "You've breathed your last!" cried the penis. "I'll not enter your establishment ever again." The Lonely Vagina Hotel would never see Mr. Penis enter again, except by way of a BACK DOOR.

      Mystery meat.

      The humming coming from the overworked pickle formed a peculiar shape as it exhaled a day's worth of soup now brought to steam.

      Slime is real?

  • (Score: 4, Interesting) by Beryllium Sphere (r) on Wednesday September 15, @01:02AM

    by Beryllium Sphere (r) (5062) on Wednesday September 15, @01:02AM (#1177915)

    "The study also focused only on safety and immunogenicity because by the time the study was implemented the West Africa Ebola outbreak had been brought under control, which meant it was not possible to evaluate the efficacy of the vaccine regimen."

    We do have reason to expect that high antibody levels go with high protection, it works that way for other things, but "immunology is where intuition goes to die".

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