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posted by martyb on Wednesday October 20 2021, @12:49PM   Printer-friendly
from the if-we-break-one,-you've-still-got-the-other dept.

Scientists partially restore vision in legally blind people with the help of CRISPR Gene- Editing - OnePexel:

Recently Scientists were able to restore vision in legally blind patients through a gene-editing experiment. Many people who were part of this experiment were born with vision issues but are now able to see betterS[sic]

Seven patients volunteered for the experiment, wherein doctors modified their DNA by injecting a gene-editing CRISPR directly into the cells. Researchers revealed on Wednesday that patients with leber congenital amaurosis (LCA), a severe form of vision impairment had their vision improved after the gene-editing therapy.

[...] Scientists had earlier used the tool to remove cells from bodies of patients, taking them to the lab for editing, and then infusing the modified cells into patients.

[...] Unlike gene-editing for other diseases, doctors infused the modified gene into the eye directly instead of in a petri dish. Until now, the patients received the CRISPR treatment only in one eye. The treatment will be extended to the other eye if all things go well.

Even then, the treatment did not repair vision for all. Doctors suspect this is due to insufficient dosage or due to too much vision damage.


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  • (Score: 0) by Anonymous Coward on Wednesday October 20 2021, @03:07PM (1 child)

    by Anonymous Coward on Wednesday October 20 2021, @03:07PM (#1188767)

    So... the steps seemed to be:
    1) scrape some eye cells out
    2) inject those cells with gene therapy directly
    3) get those cells back into the eye... somehow

    That seems... uhg...

    • (Score: 2) by DannyB on Wednesday October 20 2021, @04:04PM

      by DannyB (5839) Subscriber Badge on Wednesday October 20 2021, @04:04PM (#1188797) Journal

      3) get those cells back into the eye... somehow

      I know of two diabetic young adults who had impaired vision. A few years ago. They got a new drug (at the time) injected into their eye. From what I hear, it wasn't pleasant, but it wasn't that bad. Nothing was removed from the eye. The treatment was remarkably helpful. If I remember correctly, it was called Eylea.

      --
      To transfer files: right-click on file, pick Copy. Unplug mouse, plug mouse into other computer. Right-click, paste.
  • (Score: 4, Interesting) by Barenflimski on Wednesday October 20 2021, @03:14PM (5 children)

    by Barenflimski (6836) on Wednesday October 20 2021, @03:14PM (#1188771)

    Well, the fact that the letters "DNA" were used in the science of this precludes 50% of the country from ever using this. For the rest of us, this sounds like a great thing. Juice me up baby.

    I don't just want to put down my glasses forever, I want to see like a 10 year old until my arthritis makes me put down my xbox controller.

    • (Score: -1, Flamebait) by Anonymous Coward on Wednesday October 20 2021, @03:48PM (2 children)

      by Anonymous Coward on Wednesday October 20 2021, @03:48PM (#1188790)

      Forget eyes, I want the dick of a 10 year old.

      • (Score: 0) by Anonymous Coward on Wednesday October 20 2021, @03:55PM

        by Anonymous Coward on Wednesday October 20 2021, @03:55PM (#1188793)

        Where do you want it - in your ear?

        Actually you don't seem real bright. A ten year old hasn't hit puberty yet. Or, at least, post-pubescent 10 year olds are kinda rare. What you probably want, is the tool of a 15 or 16 year old. Is your name Ben Dover?

      • (Score: 0) by Anonymous Coward on Wednesday October 20 2021, @07:02PM

        by Anonymous Coward on Wednesday October 20 2021, @07:02PM (#1188872)

        We told you, Joe. You can sniff but don't touch. At least not on camera.

    • (Score: 1, Funny) by Anonymous Coward on Wednesday October 20 2021, @05:13PM (1 child)

      by Anonymous Coward on Wednesday October 20 2021, @05:13PM (#1188825)

      Which country?

      • (Score: 1, Funny) by Anonymous Coward on Wednesday October 20 2021, @06:14PM

        by Anonymous Coward on Wednesday October 20 2021, @06:14PM (#1188848)

        Russia of course

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