from the drown-her-past-regrets-in-coffee-and-cigarettes dept.
Coffee and cigarettes: UF Health research sheds new light on nicotine and morning brew:
For some smokers, the first cigarette of the day is just not as satisfying without a cup of coffee. That could be more than just a morning habit: Chemical compounds in roasted coffee beans may help lighten the effects of morning nicotine cravings, University of Florida [UF] researchers have found.
In a cell-based study, the researchers identified two compounds in coffee that directly affect certain high-sensitivity nicotine receptors in the brain. In smokers, these brain receptors can be hypersensitive after a night of nicotine withdrawal.
The recently published findings have yet to be tested in humans but are an important step toward better understanding how coffee and cigarettes affect nicotine receptors in the brain, said Roger L. Papke, Ph.D., a pharmacology professor in the UF College of Medicine. Caffeine is coffee's feel-good ingredient for most people but smokers may get another kind of boost.
[...] The findings have led Papke to a broader hypothesis: One of the compounds in brewed coffee, known as n-MP, may help to quell morning nicotine cravings.
[...] The findings, he said, provide a good foundation for behavioral scientists who could further study nicotine withdrawal in animal models.
Journal Reference:
Roger L. Papkea, Madison Karaffaa, Nicole A. Horenstein, et al. Coffee and cigarettes: Modulation of high and low sensitivity α4β2 nicotinic acetylcholine receptors by n-MP, a biomarker of coffee consumption☆, Neuropharmacology, 216, 2022. DOI: 10.1016/j.neuropharm.2022.109173
(Score: 5, Interesting) by mcgrew on Tuesday August 23 2022, @06:14PM (1 child)
Not just why the first cigarette of the morning is more satisfying with coffee, but why coffee was a kind of crutch when I gave up cigarettes.
From 2003: How to quit smoking cigarettes [mcgrewbooks.com]
Carbon, The only element in the known universe to ever gain sentience
(Score: 2) by bmimatt on Thursday August 25 2022, @04:18PM
I've used the same patch methodology that worked for you. To resolve the 'random' urges, I've used nicotine gum. 5 seconds of the gum in your mouth and the urge is satisfied. It's great if you know your rituals, like smoking after eating food, or with a drink. This was a game changer for me, after a few unsuccessful attempts with patch-only strategy.
(Score: 1, Funny) by Anonymous Coward on Tuesday August 23 2022, @06:33PM
As noted once before [soylentnews.org]: " It is no coincidence that modern physics was not invented until tobacco and coffee reached England."
--
"Pipe smoking contributes to a somewhat calm and objective judgment of human affairs." -Albert Einstein
(Score: 0) by Anonymous Coward on Tuesday August 23 2022, @07:39PM (2 children)
Seems pretty clear by now that smoking tobacco is bad for people. I'm sorry for all the addicts out there, it's shame that you were sucked in.
Why are we (as a society) funding further research into smoking? Wouldn't the money be better spent on smoking cessation?
(Score: 4, Touché) by DeathMonkey on Tuesday August 23 2022, @09:14PM
Seems like reducing cravings could have some applications in the cessation realm....
(Score: 1, Informative) by Anonymous Coward on Tuesday August 23 2022, @10:45PM
Last line in TFS:
(Score: 2, Funny) by Dichzor on Wednesday August 24 2022, @08:25AM
I was under impression that caffeine and nicotine were each others.. what was the word,.. one lowers the concentration of the other in the bloodstream...
Hence the craving for one, when one has taken the other.
This shows that the relationship is more non-linear then that and there are built in mechanisms for regulating.
Which totally makes sense, seeing how useful it is to hack adenosine and acetylcholine systems...
Now where are my wetware implants that i can press on with a finger and have them release half a gram of caffeine mixed with L-theanine from one, and maybe like 40 mg nicotine from the other into my bloodstream?!
One behind each ear...
(Score: 0) by Anonymous Coward on Wednesday August 24 2022, @07:24PM
Also known as a "tart's breakfast."