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posted by Dopefish on Tuesday February 18 2014, @07:00AM   Printer-friendly
from the science-rules dept.

ticho writes:

"For the first time, a team of chemists and engineers at Penn State University have placed tiny synthetic motors inside live human cells, propelled them with ultrasonic waves, and steered them magnetically. It's not exactly 'Fantastic Voyage', but it's close. The nanomotors, which are rocket-shaped metal particles, move around inside the cells, spinning and battering against the cell membrane.

'As these nanomotors move around and bump into structures inside the cells, the live cells show internal mechanical responses that no one has seen before,' said Tom Mallouk, Evan Pugh Professor of Materials Chemistry and Physics at Penn State. 'This research is a vivid demonstration that it may be possible to use synthetic nanomotors to study cell biology in new ways. We might be able to use nanomotors to treat cancer and other diseases by mechanically manipulating cells from the inside. Nanomotors could perform intracellular surgery and deliver drugs non-invasively to living tissues.'"

 
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  • (Score: 5, Insightful) by lubricus on Tuesday February 18 2014, @08:56AM

    by lubricus (232) on Tuesday February 18 2014, @08:56AM (#1487)

    This research is a vivid demonstration that it may be possible to use synthetic nanomotors to study cell biology in new ways.

    Don't get me wrong, this is cool research and very promising for a lot of things, (I agree with the above),but it's sad that researchers always feel like they have to add this to the end of every paper:

    We might be able to use nanomotors to treat cancer and other diseases by mechanically manipulating cells from the inside. Nanomotors could perform intracellular surgery and deliver drugs non-invasively to living tissues.

    This is really a judgement by the researchers on the public, for whom the only reason to do biological research is cancer. Only cancer. Does this cure cancer?

    Sad but savvy I guess.

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  • (Score: 5, Insightful) by juniorkindergarten on Tuesday February 18 2014, @09:25AM

    by juniorkindergarten (1198) on Tuesday February 18 2014, @09:25AM (#1497)

    Cancer research is where the money is. If you want funding for your idea and you can make it part of cancer research, then you have a better chance of funding. Not to say that other diseases such as diabetes don't get funding, or as much, its just that cancer is a strong rallying cry for funding.

    • (Score: 5, Insightful) by combatserver on Tuesday February 18 2014, @10:47AM

      by combatserver (38) on Tuesday February 18 2014, @10:47AM (#1520)

      "...or as much, its just that cancer is a strong rallying cry for funding."

      It's a shame that a cure would put a stop to all that wonderful funding.

      --
      I hope I can change this later...
      • (Score: 1) by FatPhil on Tuesday February 18 2014, @12:54PM

        by FatPhil (863) <{pc-soylent} {at} {asdf.fi}> on Tuesday February 18 2014, @12:54PM (#1565) Homepage

        While there are large numbers of tubbies in the world, there will always be a diabetes budget...

        --
        Great minds discuss ideas; average minds discuss events; small minds discuss people; the smallest discuss themselves
        • (Score: 0) by Anonymous Coward on Wednesday February 19 2014, @03:45AM

          by Anonymous Coward on Wednesday February 19 2014, @03:45AM (#2132)

          Nonsense. If someone developed a custom biological prosthetic pancreas that didn't have the same vulnerabilities to diabetic functioning that our naturally occurring kidneys have, and it was done in an affordable manner with minimal side effects (if any), it'd pretty quickly put a damper on further diabetes research.

          Cures have a tendency of doing that, regardless of the disease in question.

    • (Score: 4, Interesting) by mrbluze on Tuesday February 18 2014, @11:22AM

      by mrbluze (49) on Tuesday February 18 2014, @11:22AM (#1532) Journal

      How would a nanomachine be useful in cancer research? I can think of a few ways:

      • Drug delivery
      • Cell lysis on activation ... strong magnets, ironically.
      • Detection

      The key would be for the machine to recognize proteins

      --
      Do it yourself, 'cause no one else will do it yourself.
      • (Score: 2, Insightful) by lubricus on Tuesday February 18 2014, @03:23PM

        by lubricus (232) on Tuesday February 18 2014, @03:23PM (#1647)

        Sure, but that's the thing. Even with this, some research which is probably more applicable to cancer research than most that proclaim it, the application is so far down the road as to be entirely speculative.

        How would a nanomachine be useful in cancer research?

        First, we're talking about nanomotors, not nanomachines. How big is that gap? One decade, two, three? We've had nano-motors for a while now, where are the programmable nanomachines everyone is always talking about?
        Drug delivery: How are the cells detected and targeted? (This is the most biggest challenge).
        Cell lysis: (See above).
        Detection: Perhaps this is the strongest prospect, but again, what is this miraculous nano machine detecting? There are dozens if not hundreds of different types of cancer cells.

        The only benefit I can think of is little roving smart-missiles taking out metastatic cells, but even then, modified viruses will probably be used before a nano machine.

        If, on the other hand you simply say that this group can control and direct nanomotors in living cells, and would like to use them to address issues in cell regulation and physiology, I could see how this would be extremely useful within 3-5 years, and I wouldn't consider that pure speculation.

        Basic research is cool! Let's try to sell it for what it is, then other cool, but non-cancer related work will be supported also.

        --
        ... sorry about the typos
        • (Score: 1) by ragequit on Tuesday February 18 2014, @03:36PM

          by ragequit (44) on Tuesday February 18 2014, @03:36PM (#1655) Journal

          I'm fairly certain that nanomachines (esp. those depicted in The Diamond Age) will require a fundamental breakthrough in physics in general. Until then, it will be "Breakthrough, nanomotors -- On the internet!"

          --
          The above views are fabricated for your reading pleasure.
  • (Score: 2, Funny) by dilbert on Tuesday February 18 2014, @02:20PM

    by dilbert (444) on Tuesday February 18 2014, @02:20PM (#1609)
    "We might be able to use nanomotors to treat cancer and other diseases by mechanically manipulating cells from the inside. Nanomotors could perform intracellular surgery and deliver drugs non-invasively to living tissues."

    If they really wanted to get funding from the government suits, they should change that line to something along the lines of we will be able to essentially remove free will from the general public by using nanomotors to stimulate dopamine creation when they obey, and stimulating pain centers in the brain when they disobey.

    I for one welcome our new nanomotor overlords.

  • (Score: 1) by NovelUserName on Tuesday February 18 2014, @05:47PM

    by NovelUserName (768) on Tuesday February 18 2014, @05:47PM (#1751)

    Part of this may simply be that cancer is the most obvious therapeutic use for something which acts like an eggbeater inside a living cell. Even scientists will be skeptical that pureeing the inside of cells would find other target diseases.

    This really strikes me as a tool to enable other research or therapies, rather than a solution by itself. I'll have to look into the research from this group, but I'd be more interested in whether these would enable long term monitoring of cell activity by acting as conductors to a sensor array of some sort. I'd be very interested in something that would enable me to make lots of electrical or optical connections to individual neurons in a way that doesn't trigger an immune response.