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Viral infections are more successful when the infection started in the morning, and disruptions to the circadian rhythm such as jet lag give viruses even better opportunities to propagate, according to a new study:
Viruses are more dangerous when they infect their victims in the morning, a University of Cambridge study suggests. The findings, published in PNAS [DOI: 10.1073/pnas.1601895113], showed viruses were 10 times more successful if the infection started in the morning. And the animal studies found that a disrupted body clock - caused by shift-work or jet lag - was always vulnerable to infection.
The researchers say the findings could lead to new ways of stopping pandemics. Viruses - unlike bacteria or parasites - are completely dependent on hijacking the machinery inside cells in order to replicate. But those cells change dramatically as part of a 24-hour pattern known as the body clock.
(Score: 3, Funny) by maxwell demon on Tuesday August 16 2016, @01:33PM
Finally, an excellent excuse to being late:
"Sorry I couldn't come earlier because of the infection risk."
:-)
The Tao of math: The numbers you can count are not the real numbers.
(Score: 2) by bob_super on Tuesday August 16 2016, @05:11PM
My T-cells are like me: don't expect them to work before breakfast.
(Score: 0) by Anonymous Coward on Tuesday August 16 2016, @01:56PM
So the mice lived on a 12 hr day-night cycle. They injected them with virus either at t=0 (lights on) or t=10 (2 hrs before lights off). Then they assessed the amount of virus present at 3, 5, 7, 9, 13 days later. So either they tested for virus at different time of day or there was an approximately half day difference in the time elapsed between infection and testing. It isn't clear from the paper which is true, but either could also explain a difference in virus count. It is also odd to me they used t=10 hrs rather than t=12 hrs. This could also have to do with stress occurring when the lights turn on/off rather than circadian rhythms.
(Score: 1) by Snort on Tuesday August 16 2016, @02:31PM
The DOI is not only a persistent identifier, it is also a linking mechanism.
http://doi.org/10.1073/pnas.1601895113 [doi.org] will take you to the publisher site. And no need to get some URL that will break as soon as the publisher updates their system.
You can also use the DOI to pull metadata about the article in apps like endnote and zotero.
Every time you use an unlinked DOI, kittens cry.
(Score: 2) by takyon on Tuesday August 16 2016, @02:46PM
If you use my extension, the formatted DOI will link to Crossref or the site of your choice.
[SIG] 10/28/2017: Soylent Upgrade v14 [soylentnews.org]
(Score: 2) by DECbot on Tuesday August 16 2016, @05:08PM
So, not only does Daylight Savings Time not save energy and is a major contributor to traffic accidents, it also puts you at risk for infection. Why do we still do this?
cats~$ sudo chown -R us /home/base
(Score: 2) by NCommander on Wednesday August 17 2016, @01:03AM
That actually explains a lot. I have a sleep disorder (Non-24 Sleep/Wake), and a broken circadian rhythm. I've very rarely if ever been sick in my life even being around those deathly ill as an EMT/Firefighter, and both my parents when our house had become a plague zone. That's ontop of the fact I've near-constantly travelled for the last eight years, and only once have I very sick (in Vietnam) from it.
Still always moving