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posted by martyb on Friday April 21 2017, @09:24AM   Printer-friendly
from the where-do-they-get-the-seeds? dept.

Arthur T Knackerbracket has found the following story:

Deprived of oxygen, naked mole-rats can survive by metabolizing fructose just as plants do, researchers report this week in the journal Science.

Understanding how the animals do this could lead to treatments for patients suffering crises of oxygen deprivation, as in heart attacks and strokes.

[...] In humans, laboratory mice, and all other known mammals, when brain cells are starved of oxygen they run out of energy and begin to die.

But naked mole-rats have a backup: their brain cells start burning fructose, which produces energy anaerobically through a metabolic pathway that is only used by plants -- or so scientists thought.

In the new study, the researchers exposed naked mole-rats to low oxygen conditions in the laboratory and found that they released large amounts of fructose into the bloodstream. The fructose, the scientists found, was transported into brain cells by molecular fructose pumps that in all other mammals are found only on cells of the intestine.

[...] At oxygen levels low enough to kill a human within minutes, naked mole-rats can survive for at least five hours... They go into a state of suspended animation, reducing their movement and dramatically slowing their pulse and breathing rate to conserve energy. And they begin using fructose until oxygen is available again.

[...] The scientists also showed that naked mole-rats are protected from another deadly aspect of low oxygen -- a buildup of fluid in the lungs called pulmonary edema that afflicts mountain climbers at high altitude.

The scientists think that the naked mole-rats' unusual metabolism is an adaptation for living in their oxygen-poor burrows. Unlike other subterranean mammals, naked mole-rats live in hyper-crowded conditions, packed in with hundreds of colony mates. With so many animals living together in unventilated tunnels, oxygen supplies are quickly depleted.

Journal Reference:
Thomas J. Park, et al.. Fructose-driven glycolysis supports anoxia resistance in the naked mole-rat. Science, 2017; 356 (6335): 307 DOI: 10.1126/science.aab3896

-- submitted from IRC


Original Submission

 
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  • (Score: 3, Informative) by Anonymous Coward on Friday April 21 2017, @02:49PM (5 children)

    by Anonymous Coward on Friday April 21 2017, @02:49PM (#497424)

    From what I remember, naked mole rats are the only one of two mammalian species that has a colony structure with a queen.

    https://en.wikipedia.org/wiki/Naked_mole-rat#Roles [wikipedia.org]
    https://en.wikipedia.org/wiki/Eusociality [wikipedia.org]

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  • (Score: 2) by fishybell on Friday April 21 2017, @03:21PM (2 children)

    by fishybell (3156) on Friday April 21 2017, @03:21PM (#497446)

    Who knew we had so much in common? All hail the queen!...I guess.

    • (Score: 2) by Hartree on Friday April 21 2017, @04:50PM

      by Hartree (195) on Friday April 21 2017, @04:50PM (#497489)

      "God save the queen! She's not a human being!"

    • (Score: 2) by maxwell demon on Saturday April 22 2017, @09:08AM

      by maxwell demon (1608) on Saturday April 22 2017, @09:08AM (#497847) Journal

      From the Wikipedia article (in the section about mammals):

      both of which are diploid and highly inbred.

      Another common trait with aristocrats.

      --
      The Tao of math: The numbers you can count are not the real numbers.
  • (Score: 0) by Anonymous Coward on Friday April 21 2017, @05:40PM

    by Anonymous Coward on Friday April 21 2017, @05:40PM (#497505)

    Anunnaki and humans being the only two technological species that have a colony structure with a queen.

    Though I guess queens are more common among anunnaki. Humans prefer kings. There have always been exceptions throughout history though.

    Two species practically made for each other.

  • (Score: 0) by Anonymous Coward on Friday April 21 2017, @08:17PM

    by Anonymous Coward on Friday April 21 2017, @08:17PM (#497570)

    one of two mammalian species

    I immediately though of alpha males and alpha females among Wolves and African Wild Dogs.

    Down in the Wikipedia article:

    Some mammals within the Carnivora and Primates exhibit eusocial tendencies. Perhaps most notable are meerkats (Suricata suricatta) and dwarf mongooses (Helogale parvula)
    [...]
    Edward O. Wilson, in his controversial [...] 2012 book, The Social Conquest of the Earth, referred to humans as a species of eusocial ape. He supported his reasoning by stating our eusocial similarities to ants, and by observing that early hominins cooperated to rear their children while other members of the same group hunted and foraged

    -- OriginalOwner_ [soylentnews.org]