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posted by martyb on Friday January 12, @12:00PM   Printer-friendly
from the the-end-is-near...-we-hope! dept.

http://www.sciencemag.org/news/2018/01/what-hell-going-polio-cases-are-vanishing-pakistan-yet-virus-wont-go-away

Just a year ago, poliovirus seemed on its last legs in Pakistan, one of its final strongholds. Polio cases were steadily falling, from 306 in 2014 to 54 in 2015, 20 in 2016, and, by last count, eight in 2017. Blood tests showed that, overall, immunity to the virus had never been higher, even among children aged 6 to 11 months, thanks to years of tireless vaccination campaigns. Surely, there were not enough susceptible kids to sustain transmission, and the virus would burn itself out within a year.

Unsettling new findings, however, show it is far from gone. In the most extensive effort in any country to scour the environment for traces of the virus, polio workers are finding it widely across Pakistan, in places they thought it had disappeared. They are wondering "just what the hell is going on" and how worried they should be, says epidemiologist Chris Maher of the World Health Organization (WHO) in Geneva, Switzerland, who runs polio operations in the eastern Mediterranean region. Does this mean the virus is more entrenched than anyone realized and is poised to resurge? Or is this how a virus behaves in its final days—persisting in the environment but not causing disease until it fades out?

[...] Along with Afghanistan and Nigeria, Pakistan is one of just three endemic countries—places where indigenous wild poliovirus has never been vanquished.

[...] Since the eradication effort began in 1988, the gold standard for detecting poliovirus has been surveillance for acute flaccid paralysis (AFP)—finding and testing every child with a sudden weakness or floppiness in the arms or legs. The yearly case count has been the benchmark for success: After 12 months without a polio case, WHO has historically removed a country from the endemic list.

Polio workers collect sewage samples, usually from open drainage ditches, and test them for virus. If the test is positive, that means someone in the catchment area is infected and actively excreting it. Pakistan now has 53 sampling sites, more than any other country. And at a time when cases are the lowest on record, 16% of samples from across the country are testing positive.

[...] One possible explanation for the disconnect is that AFP surveillance is missing cases. Maher doubts that the number is significant, but others suspect that too many children among the mobile populations, including the marginalized Pashtun minority, still aren't being vaccinated despite ramped up efforts to reach them. "I don't think polio is entrenched across Pakistan, but this last reservoir of 'people on the move' is sustaining the virus," says Steve Cochi, a polio expert at the U.S. Centers for Disease Control and Prevention in Atlanta.

[...] The program is not taking any chances. The response to each positive environmental test is now as aggressive as to a case of paralysis. And the program is hammering the virus with repeated vaccination campaigns throughout the "low season," between December and May, when cold weather makes it tougher for the virus to survive. Whether the strategy works will become clear later this year when the weather turns warm. But one thing is certain: The absence of cases is no longer enough to declare victory over polio. Going forward, a country will not be considered polio-free until 12 months have passed without a case—or a positive environmental sample.


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  • (Score: 5, Informative) by inertnet on Friday January 12, @01:58PM (7 children)

    by inertnet (4071) on Friday January 12, @01:58PM (#621365)

    When the USA tracked down Bin Laden, they used a fake vaccination program in order to collect blood samples for testing. Since then many people in Pakistan are still distrustful against vaccination programs. A lot of Red Cross volunteers still get killed there because of this distrust, for example Six Red Cross workers killed [theguardian.com].

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  • (Score: 4, Insightful) by Anonymous Coward on Friday January 12, @02:04PM (2 children)

    by Anonymous Coward on Friday January 12, @02:04PM (#621370)

    When people already expect the push for vaccines is part of some kind of nefarious conspiracy, it really doesn't help to prove them right...

    • (Score: 0) by Anonymous Coward on Friday January 12, @09:07PM

      by Anonymous Coward on Friday January 12, @09:07PM (#621562)

      Yeah, it was a dumb idea, Bin Laden couldn't have hurt as many people as Polio did no matter how hard he tried.

    • (Score: 2, Troll) by realDonaldTrump on Friday January 12, @09:11PM

      by realDonaldTrump (6614) Subscriber Badge on Friday January 12, @09:11PM (#621564) Homepage Journal

      It's bad in many ways. On many sides. Some vaccines are very important. But autism has become an epidemic. It has gotten totally out of control. Pakistan, after getting more than 33 billion dollars in aid over the last 15 years, have given us nothing but lies & deceit, thinking of our leaders as fools. They give safe haven to the terrorists we hunt in Afghanistan, with little help from that shithole country. But President Obama and the Deep State did a terrible thing. They were just as deceitful.

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  • (Score: 3, Insightful) by tangomargarine on Friday January 12, @05:27PM

    by tangomargarine (667) on Friday January 12, @05:27PM (#621455)

    One of the most horribly, blatantly unethical things our government has done. Just disgusting.

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  • (Score: 0) by Anonymous Coward on Friday January 12, @07:52PM (2 children)

    by Anonymous Coward on Friday January 12, @07:52PM (#621515)

    We used a real vaccination program. We were delivering real working vaccines. You make us out to be so evil, but we were vaccinating the children of our worst enemy.

    • (Score: 0) by Anonymous Coward on Friday January 12, @09:35PM (1 child)

      by Anonymous Coward on Friday January 12, @09:35PM (#621571)

      Im sure youd get a real vaccine right along with the secret sterilization shot.

      • (Score: 0) by Anonymous Coward on Friday January 12, @10:29PM

        by Anonymous Coward on Friday January 12, @10:29PM (#621583)

        I'm not saying this was a case where sterilization was done, but the US has been known to sterilize the population in the past. Specifically Native Americans and the mentally handicapped, probably others too.