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posted by janrinok on Monday June 04 2018, @05:22AM   Printer-friendly
from the earlier-detection-=-improved-outcome dept.

'Holy grail of cancer research': doctors positive about early detection blood test

A blood test for 10 different types of cancers could one day help doctors screen for the disease before patients show symptoms, researchers at the world's largest gathering of oncologists have said.

The test, called a liquid biopsy, screens for cancer by detecting tiny bits of DNA released by cancer cells into blood. The test had particularly good results for ovarian and pancreatic cancers, though the number of cancers detected was small.

Researchers hope the test will become part of a "universal screening" tool that doctors can use to detect cancer in patients.

"This is potentially the holy grail of cancer research, to find cancers that are currently hard to cure at an earlier stage when they are easier to cure," said Dr Eric Klein, lead author of the research from Cleveland Clinic's Taussig Cancer Institute. "We hope this test could save many lives."

Also at CNN.

Development of a comprehensive cell-free DNA (cfDNA) assay for early detection of multiple tumor types: The Circulating Cell-free Genome Atlas (CCGA) study. (abstract only)


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  • (Score: 1, Interesting) by Anonymous Coward on Monday June 04 2018, @08:16AM

    by Anonymous Coward on Monday June 04 2018, @08:16AM (#688282)

    Once the test gets sensitive enough they will discover that cancer cell lineages are forming and resolving (either self destruct, enter senescence, or get killed by the immune system) all the time.

    Since armitage and doll came up with the multistage theory (1954) a big assumption has been that tumorigenesis is the rate limiting step (rather than surviving to the point of causing problems for the host) and its funny because they only did that to make the math easier in the pre computer age. Bad base assumptions like that are why cancer researchers have largely given up, saying its so super duper complex and not even a single disease anymore and that's why we can't cure it. A perfect example of one of Lakatos' degenerating research programmes.

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