Stories
Slash Boxes
Comments

SoylentNews is people

Saccharin Derivatives Give Cancer Cells A Not-So-Sweet Surprise

posted by Fnord666 on Saturday December 21 2019, @08:56PM   Printer-friendly
from the pink-is-good dept.

Arthur T Knackerbracket writes:

Arthur T Knackerbracket has found the following story:

Saccharin received a bad rap after studies in the 1970s linked consumption of large amounts of the artificial sweetener to bladder cancer in laboratory rats. Later, research revealed that these findings were not relevant to people. And in a complete turnabout, recent studies indicate that saccharin can actually kill human cancer cells. Now, researchers reporting in ACS' Journal of Medicinal Chemistry have made artificial sweetener derivatives that show improved activity against two tumor-associated enzymes.

Journal Reference:

Silvia Bua, et. al.“A Sweet Combination”: Developing Saccharin and Acesulfame K Structures for Selectively Targeting the Tumor-Associated Carbonic Anhydrases IX and XII. Journal of Medicinal Chemistry, 2019; DOI: 10.1021/acs.jmedchem.9b01669

Original Submission

 
This discussion has been archived. No new comments can be posted.
Saccharin Derivatives Give Cancer Cells A Not-So-Sweet Surprise | Log In/Create an Account | Top | 12 comments | Search Discussion
Display Options Threshold/Breakthrough Mark All as Read Mark All as Unread
The Fine Print: The following comments are owned by whoever posted them. We are not responsible for them in any way.

  • (Score: 4, Touché) by Azuma Hazuki on Sunday December 22 2019, @12:04AM

    by Azuma Hazuki (5086) on Sunday December 22 2019, @12:04AM (#935090) Journal

    ...when was saccharin introduced, idiot? Go on, look it up.

    --
    I am "that girl" your mother warned you about...
    Starting Score:    1  point
    Moderation   +2  
       Disagree=1, Touché=2, Total=3
    Extra 'Touché' Modifier   0  
    Karma-Bonus Modifier   +1  
    Total Score:   4