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Saccharin Derivatives Give Cancer Cells A Not-So-Sweet Surprise

posted by Fnord666 on Saturday December 21 2019, @08:56PM   
from the pink-is-good dept.

Arthur T Knackerbracket writes:

Arthur T Knackerbracket has found the following story:

Saccharin received a bad rap after studies in the 1970s linked consumption of large amounts of the artificial sweetener to bladder cancer in laboratory rats. Later, research revealed that these findings were not relevant to people. And in a complete turnabout, recent studies indicate that saccharin can actually kill human cancer cells. Now, researchers reporting in ACS' Journal of Medicinal Chemistry have made artificial sweetener derivatives that show improved activity against two tumor-associated enzymes.

Journal Reference:

Silvia Bua, et. al.“A Sweet Combination”: Developing Saccharin and Acesulfame K Structures for Selectively Targeting the Tumor-Associated Carbonic Anhydrases IX and XII. Journal of Medicinal Chemistry, 2019; DOI: 10.1021/acs.jmedchem.9b01669

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Original Submission

• Re:Aspartame Re:Aspartame (Score: 1, Interesting) by Anonymous Coward on Sunday December 22 2019, @02:07AM (1 child)

  by Anonymous Coward on Sunday December 22 2019, @02:07AM (#935112)

  OK, so I went and actually read the article and apparently everything I said was wrong. Sorry about this.

  Parent

  Starting Score:	0		points
  Moderation		+1
  Interesting=1, Total=1
  Extra 'Interesting' Modifier		0
  Total Score:		1

• Re:Aspartame (Score: 3, Insightful) by RS3 on Sunday December 22 2019, @05:05AM

  by RS3 (6367) on Sunday December 22 2019, @05:05AM (#935134)

  It's okay- you stimulate people's interest and thinking.

  Parent