Lustig, the maverick scientist, has long argued that sugar is as harmful as cocaine or tobacco – and that the food industry has been adding too much of it to our meals for too long.
If you have any interest at all in diet, obesity, public health, diabetes, epidemiology, your own health or that of other people, you will probably be aware that sugar, not fat, is now considered the devil's food. Dr Robert Lustig's book, Fat Chance: The Hidden Truth About Sugar, Obesity and Disease ( http://www.theguardian.com/books/2013/jan/25/fat-chance-robert-lustig-review ), for all that it sounds like a Dan Brown novel, is the difference between vaguely knowing something is probably true, and being told it as a fact. Lustig has spent the past 16 years treating childhood obesity. His meta-analysis of the cutting-edge research on large-cohort studies of what sugar does to populations across the world, alongside his own clinical observations, has him credited with starting the war on sugar. When it reaches the enemy status of tobacco, it will be because of Lustig.
http://www.theguardian.com/lifeandstyle/2014/aug/24/robert-lustig-sugar-poison
I think moderation is the key. What do you think ?
(Score: 1) by cout on Wednesday August 27 2014, @05:32PM
The second step of glycolysis is metabolism from glucose-6-phosphate to fructose-6-phospate, not fructose. When fructose is metabolized, it is phosphorylated by fructokinase to fructose-1-phosphate. So yes, glucose is metabolized to a phosphorylated to a 5-carbon-ring sugar, but the phosphate group is on a different carbon when glucose is metabolized than when fructose is metabolized. In other words, the pathways differ until the sugars are broken down into three-carbon molecules.
(apparently hexokinase can metabolize fructose to fructose-6-P, but it is a slower reaction and is therefore a less likely reaction).