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posted by janrinok on Thursday March 12 2020, @08:32PM   Printer-friendly
from the Tomorrow-is-Friday-the-13th dept.

Even though it has only been a short while since our last round-up there are 22 separate stories merged into this round-up. Many report duplicate news but, nevertheless, we have tried to distill the important elements of each submission.

Firstly, there is some confusion regarding the actual names that are reported for the virus, the disease that it causes, and names frequently seen in media reporting. From https://www.nature.com/articles/s41564-020-0695-z:

The present outbreak of a coronavirus-associated acute respiratory disease called coronavirus disease 19 (COVID-19) is the third documented spillover of an animal coronavirus to humans in only two decades that has resulted in a major epidemic. The Coronaviridae Study Group (CSG) of the International Committee on Taxonomy of Viruses, which is responsible for developing the classification of viruses and taxon nomenclature of the family Coronaviridae, has assessed the placement of the human pathogen, tentatively named 2019-nCoV, within the Coronaviridae. Based on phylogeny, taxonomy and established practice, the CSG recognizes this virus as forming a sister clade to the prototype human and bat severe acute respiratory syndrome coronaviruses (SARS-CoVs) of the species Severe acute respiratory syndrome-related coronavirus, and designates it as SARS-CoV-2.

In order to facilitate communication, the CSG proposes to use the following naming convention for individual isolates: SARS-CoV-2/host/location/isolate/date. While the full spectrum of clinical manifestations associated with SARS-CoV-2 infections in humans remains to be determined, the independent zoonotic transmission of SARS-CoV and SARS-CoV-2 highlights the need for studying viruses at the species level to complement research focused on individual pathogenic viruses of immediate significance. This will improve our understanding of virus–host interactions in an ever-changing environment and enhance our preparedness for future outbreaks.

There is much more information at the link provided.

Secondly, as this is a fusion of stories received over the last week or so take all quoted figures of casualties as possibly out-of-date. At the time of merging these stories (12 Mar 20) there have been 127,863 confirmed cases world-wide resulting in 4,717 deaths. 68,309 people have already recovered with the remainder either in self-imposed or advisory isolation, in basic hospital care and a relatively small number in critical care. The pandemic has affected 116 countries/regions. Source: https://www.arcgis.com/apps/opsdashboard/index.html#/bda7594740fd40299423467b48e9ecf6 - a graphical display produced by Johns Hopkins University (JHU).

Many countries have taken emergency measures to restrict travel or large gatherings of people. As this is a very fluid situation we suggest you refer to the media of any specific country in which you have an interest. President Trump has banned transatlantic air travel from countries in mainland Europe to the USA from Friday 2020-03-13 at 23:59 (no timezone stated) for a period initially of 30 days, and air travel within Europe is also significantly disrupted.

Coronavirus can live in the air for three hours, survive on surfaces for two to three days - UPI.com

According to new research, the novel coronavirus can remain in the air for up to 3 hours and survive on some surfaces for two to three days.

Source: https://www.upi.com/Science_News/2020/03/11/Coronavirus-can-live-in-air-for-3-hours-on-surfaces-for-2-3-days/8121583963038/

Derek Lowe on Coronavirus

The esteemed Derek Lowe talks Coronavirus.

Since this is going to be a post about the coronavirus, let's start off with this PSA: wash your hands. These viruses have a lipid envelope that is crucial to their structure and function, and soaps and detergents are thus very effective at inactivating them. It's fast, it's simple, and it's one of the more useful things that any individual can do under these conditions.

Coronavirus COVID-19 Declared to be a pandemic

The World Health Organization has declared COVID-19 to be a pandemic. This may mean that some types of insurance may no longer be valid for medical treatment. Italy is now locked down and many other countries now have cases including Australia where there the virus has now reached all states.

Prepare for the worst, hope for the best.

Trump Announces New Agreements From Health Insurance Companies Amid Wuhan Virus Spread

Trump announced that ten major health insurance companies have agreed to fully cover testing for Wuhan virus, without co-pays. He is following that with an effort to help hourly wage earners avoid missing paychecks due to the epidemic.

Coronavirus: NHS Targets Fake News Spreading Online

Arthur T Knackerbracket has found the following story:

The decision to delay closing schools and introduce other strict measures to combat coronavirus has been defended by England's deputy chief medical officer.

Dr Jenny Harries said experts are assessing new cases on an hourly basis to achieve a "balanced response".

The NHS has unveiled a range of measures as part of its response to try to stop fake news being spread about coronavirus on the internet.

Searches for "coronavirus" on Google, Facebook and YouTube will now promote information from the National Health Service or the World Health Organization.

The NHS said it had worked with Twitter to take down an account claiming to be a hospital and spreading false information, while it is also speaking out against homeopaths promoting false treatments online.

Health Secretary Matt Hancock said the actions meant the public could access accurate health information "which is more crucial than ever as we continue our response to coronavirus".

The UK is currently in the first phase - "containment" - of the government's four-part plan.

On Monday, health officials said people who showed "even minor" signs of respiratory tract infections or a fever would soon be told to self-isolate for seven days in an effort to tackle the outbreak.

The change in advice could happen within the next 10 to 14 days, the UK's chief medical adviser Prof Chris Whitty said.

It came after researchers in the US found it took five days for most people with coronavirus to show symptoms.

Prime Minister Boris Johnson also suggested the elderly and vulnerable could be asked to stay home in the near future.

[Editor's Note: In the budget announcement in Parliament yesterday (11 Mar) the Government announced billions of pounds of measures to support businesses during the crisis, and to ensure that anyone who is advised to self-isolate can receive state sickness payments from the start of the absence from their place of work. The UK Cobra (Emergency Committee) are sitting as I edit this round-up and may well announce new measures to address the pandemic in the next few hours and days]

Apple Reportedly Offers Retail Workers Unlimited Sick Leave for Coronavirus Symptoms

Apple reportedly offers retail workers unlimited sick leave for coronavirus symptoms:

Days after the coronavirus outbreak prompted Apple CEO Tim Cook to let his employees work from home, 9to5Mac reported that the company's retail and hourly workers are getting unlimited sick leave if they experience the pneumonia-like symptoms linked to the disease.

These workers won't need to give managers a doctor's note either. Apple Stores are remaining open despite the outbreak, but 9to5Mac noted that company is canceling some Today at Apple sessions and other gatherings to limit crowds.

Italy Extends Coronavirus Lockdown to Entire Country

Italy extends coronavirus lockdown to entire country:

Italian Prime Minister Giuseppe Conte announced Monday that the government has extended internal travel restrictions to the entire country until April 3, after initially locking down the country's northern region in an effort to contain the coronavirus.

Why it matters: It's an extreme measure that effectively locks down 60 million people in one of the most populated countries in Europe, where more people have tested positive for the coronavirus than any country outside of China. Conte also announced that all public gatherings and sporting events would be banned.

Xi Visits Wuhan

Xi visits Wuhan, Italy under coronavirus quarantine: Live updates:

Chinese President Xi Jinping has visited Wuhan, the epicentre of the coronavirus outbreak, the first time he has done so since the epidemic began and a sign that Beijing believes its efforts to control the virus are working.

His arrival in the city comes after its spread in mainland China has sharply slowed in the past week and as attention has turned to preventing imported infections from overseas hot spots such as Iran, Italy and South Korea.

Authorities in China's Hubei said on Tuesday they will implement a "health code" mobile-phone-based monitoring system to start allowing people to travel within the province, as it tries to get life back to normal.

The statement, published on the government's website, said the move was aimed at promoting the resumption of work and production.

China's President Xi Jinping arrived in the provincial capital, Wuhan, on Tuesday for his first visit and is meeting medical workers and others involved in the fight against the virus.

FDA / NY Atty Gen Order Jim Bakker to Stop Selling Fraudulent Coronavirus Products

FDA warns televangelist Jim Bakker and six others to stop selling fraudulent coronavirus products

The Food and Drug Administration said Monday it has sent warning letters to televangelist Jim Bakker and six companies for selling unapproved coronavirus drugs and treatment products.

"The FDA considers the sale and promotion of fraudulent COVID-19 products to be a threat to the public health. We have an aggressive surveillance program that routinely monitors online sources for health fraud products, especially during a significant public health issue such as this one," FDA Commissioner Stephen M. Hahn said in announcing the enforcement actions.

The products include teas, essential oils, tinctures and colloidal silver, which have been cited as not safe or effective for treating any disease, the agency said in a statement with the Federal Trade Commission.

The FDA said it was particularly worried that the products may cause people to delay or stop appropriate treatment, "leading to serious and life-threatening harm."

See also: NY attorney general orders televangelist Jim Bakker to stop promoting alleged coronavirus cure

Covid-19 Small Molecule Therapies Reviewed

Covid-19 Small Molecule Therapies Reviewed:

Let's take inventory on the therapies that are being developed for the coronavirus epidemic. Here is a very thorough list of at Biocentury, and I should note that (like Stat and several other organizations) they're making all their Covid-19 content free to all readers during this crisis. I'd like to zoom in today on the potential small-molecule therapies, since some of these have the most immediate prospects for use in the real world.

The ones at the front of the line are repurposed drugs that are already approved for human use, for a lot of obvious reasons. The Biocentury list doesn't cover these, but here's an article at Nature Biotechnology that goes into detail. Clinical trials are a huge time sink – they sort of have to be, in most cases, if they're going to be any good – and if you've already done all that stuff it's a huge leg up, even if the drug itself is not exactly a perfect fit for the disease. So what do we have? The compound that is most advanced is probably remdesivir from Gilead, at right. This has been in development for a few years as an RNA virus therapy – it was originally developed for Ebola, and has been tried out against a whole list of single-strand RNA viruses. That includes the related coronaviruses SARS and MERS, so Covid-19 was an obvious fit.

The compound is a prodrug – that phosphoramide gets cleaved off completely, leaving the active 5-OH compound GS-44-1524. It mechanism of action is to get incorporated into viral RNA, since it's taken up by RNA polymerase and it largely seems to evade proofreading. This causes RNA termination trouble later on, since that alpha-nitrile C-nucleoside is not exactly what the virus is expecting in its genome at that point, and thus viral replication is inhibited.

There are five clinical trials underway (here's an overview at Biocentury). The NIH has an adaptive-design Phase II trial that has already started in Nebraska, with doses to be changed according to Bayesian readouts along the way. There are two Phase III trials underway at China-Japan Friendship Hospital in Hubei, double-blinded and placebo-controlled (since placebo is, as far as drug therapy goes, the current standard of care). And Gilead themselves are starting two open-label trials, one with no control arm and one with an (unblinded) standard-of-care comparison arm. Those might read out first, depending on when they get off the ground, but will be only rough readouts due to the fast-and-loose trial design. The two Hubei trials and the NIH one will add some rigor to the process, but I'm not sure when they're going to report. My personal opinion is that I like the chances of this drug more than anything else on this list, but it's still unlikely to be a game-changer.

There's an RNA polymerase inhibitor (favipiravir) from Toyama, at right, that's in a trial in China. It's a thought – a broad-spectrum agent of this sort would be the sort of thing to try. But unfortunately, from what I can see, it has already turned up as ineffective in in vitro tests. The human trial that's underway is honestly the sort of thing that would only happen under circumstances like the present: a developing epidemic with a new pathogen and no real standard of care. I hold out little hope for this one, but given that there's nothing else at present, it probably should be tried. As you'll see, this is far from the only situation like this.

[...] There are several other known antiviral drugs [that] are being tried in China, but I don't have too much hope for those, either. The neuraminidase inhibitors such as oseltamivir (better known as Tamiflu) were tried against SARS and were ineffective; there is no reason to expect anything versus Covid-19 although these drugs are a component of some drug cocktail trials. The HIV protease therapies such as darunavir and the combination therapy Kaletra are in trials, but that's also a rather desperate long shot, since there's no particular reason to think that they will have any such protease inhibition against what this new virus has to offer (and indeed, such agents weren't much help against SARS in the end, either). The classic interferon/ribavirin combination seems to have had some activity against SARS and MERS, and is in two trials from what I can see. That's not an awful idea by any means, but it's not a great one, either: if your viral disease has interferon/ribavirin as a front line therapy, it generally means that there's nothing really good available. No, unless we get really lucky none of these ideas are going to slow the disease down much.

There are a few other repurposed-protease-inhibitors ideas out there, such as this one. (Edit: I had seen this paper but couldn't track it down, so thanks to those who sent it along). This paper suggests that the TMPRSS2 protease is important for viral entry on the human-cell-side of the process, a pathway that has been noted for other coronaviruses. And it points out that there is a an approved inhibitor (in Japan) for this enzyme (camostat), so that would definitely seem to be worth a trial, probably in combination with remdesivir.

That's about it for the existing small molecules, from what I can see. What about new ones? Don't hold your breath, is all I can say. A drug discovery program from scratch against a new pathogen is, as many readers here well know, not a trivial exercise. As this Bloomberg article details, many such efforts in the past (small molecules and vaccines alike) have come to grief because by the time they had anything to deliver the epidemic itself had passed. Indeed, Gilead's remdesivir had already been dropped as a potential Ebola therapy.

You will either need to have a target in mind up front or go phenotypic. For the former, what you'd see are better characterizations of the viral protease and more extensive screens against it. Two other big target areas are viral entry (which involves the "spike" proteins on the virus surface and the ACE2 protein on human cells) and viral replication. To the former, it's worth quickly noting that ACE2 is so much unlike the more familiar ACE protein that none of the cardiovascular ACE inhibitors do anything to it at all. And targeting the latter mechanisms is how remdesivir was developed as a possible Ebola agent, but as you can see, that took time, too. Phenotypic screens are perfectly reasonable against viral pathogens as well, but you'll need to put time and effort into that assay up front, just as with any phenotypic effort, because as anyone who does that sort of work will tell you, a bad phenotypic screen is a complete waste of everyone's time.

[...] All this means that any new-target new-chemical-matter effort against Covid-19 (or any new pathogen) is going to take years, and there is just no way around that. This puts small molecules in a very bimodal distribution: you have the existing drugs that might be repurposed, and are presumably available right now. Nothing else is! At the other end, for completely new therapies you have the usual prospects of drug discovery: years from now, lots of money, low success rate, good luck to all of us. The gap between these two could in theory be filled by vaccines and antibody therapies (if everything goes really, really well) but those are very much their own area and will be dealt with in a separate post.

Chinese Robot Is Designed to Help Doctors Fight Coronavirus

Chinese researchers have developed a robot designed to help doctors treat the new coronavirus and other highly contagious diseases.

The machine has a long robotic arm attached to a base with wheels. It can perform some of the same medical examination tasks as doctors. For example, the device can perform ultrasounds, collect fluid samples from a person's mouth and listen to sounds made by a patient's organs.

Cameras record the robot's activities, which are controlled remotely so doctors can avoid coming in close contact with infected patients. Doctors and other medical workers can operate the machine from a nearby room, or from much farther away.

The robot's main designer is Zheng Gangtie, an engineer and professor at China's Tsinghua University in Beijing. He told Reuters news agency that he got the idea for the device around the time of the Lunar New Year in January. At the time, the number of cases of the COVID-19 virus was rising quickly in the city of Wuhan. COVID-19 is the disease caused by the new coronavirus.

Zheng said a friend of his is the head of Beijing's Tsinghua Changgung Hospital. He said his friend told him that one of the biggest problems in dealing with COVID-19 was that healthcare workers treating patients were getting infected themselves. Zheng said he wanted to do something to help this situation.

So the engineer gathered a team and went to work on the robotic device. Zheng said the team was able to convert two robotic arms. The devices use the same technology that is used for space equipment, including moon explorers. The new robot is almost completely automated, Zheng said. It can even disinfect itself after performing actions involving patient contact.

Greece Closes Borders to Millions of Migrants from Turkey as Coronavirus Fears Escalate

Turkey has allowed millions of undocumented migrants to cross into Greece as the coronavirus takes hold in Iran and enters Europe. With more countries around the world reporting cases of infection Turkey, going back on its billion dollar agreement to contain undocumented migrants at its borders, is now assisting migrants to enter Greece. Greek officials are already struggling to manage the undocumented arrivals and provide sufficient care to them in the wake of what looks like a global pandemic. With hundreds of thousands of migrants trying to enter the country locals are repelling boats and border guards are shooting riot gas. At least one undoc has been killed trying to cross the Greek border. The situation is causing panic in Greece as people prepare for the impact of Covid-19.

List N: Disinfectants for Use Against SARS-CoV-2

List N: Disinfectants for Use Against SARS-CoV-2:

The EPA-registered disinfectant products on this list have qualified under EPA's emerging viral pathogen program for use against SARS-CoV-2, a coronavirus that causes COVID-19. Coronaviruses are enveloped viruses, meaning they are one of the easiest types of viruses to kill with the appropriate disinfectant product. The emerging viral pathogen guidance was triggered for SARS-CoV-2 on January 29, 2020.

EPA strongly recommends following the product label use directions for enveloped viruses, as indicated by the approved emerging viral pathogen claim on the master label. If the directions for use for viruses/virucidal activity list different contact times or dilutions, use the longest contact time or most concentrated solution.

Don't Panic: The comprehensive Ars Technica guide to the coronavirus

[Ed. note: This story is being actively maintained with daily updates. --martyb]

https://arstechnica.com/science/2020/03/dont-panic-the-comprehensive-ars-technica-guide-to-the-coronavirus

More than 100,000 people have been infected with a new coronavirus that has spread widely from its origin in China over the past few months. More than 3,000 have already died. Our comprehensive guide for understanding and navigating this global public health threat is below.

[...] You should be concerned and take this seriously. But you should not panic.

This new coronavirus—dubbed SARS-CoV-2—is unquestionably dangerous. It causes a disease called COVID-19, which can be deadly, particularly for older people and those with underlying health conditions. While the death rate among infected people is unclear, even some current low estimates are seven-fold higher than the estimate for seasonal influenza.

[...] Coronaviruses are a large family of viruses that get their name from the halo of spiked proteins that adorn their outer surface, which resemble a crown (corona) under a microscope. As a family, they infect a wide range of animals, including humans.

[...] SARS-CoV-2 is related to coronaviruses in bats, but its intermediate animal host and route to humans are not yet clear. There has been plenty of speculation that the intermediate host could be pangolins, but that is not confirmed.

While the identity of SARS-CoV-2's intermediate host remains unknown, researchers suspect the mystery animal was present in a live animal market in Wuhan, China—the capital city of China's central Hubei Province and the epicenter of the outbreak. The market, which was later described in Chinese state media reports as "filthy and messy," sold a wide range of seafood and live animals, some wild. Many of the initial SARS-CoV-2 infections were linked to the market; in fact, many early cases were in people who worked there.

[...] That said, a report in The Lancet describing 41 early cases in the outbreak indicates that the earliest identified person sickened with SARS-CoV-2 had no links to the market. As Ars has reported before, the case was in a man whose infection began causing symptoms on December 1, 2019. None of the man's family became ill, and he had no ties to any of the other cases in the outbreak.

[...] In people, SARS-CoV-2 causes a disease dubbed COVID-19 by the World Health Organization (WHO). As the US Centers for Disease Control and Prevention (CDC) points out, the 'CO' stands for 'corona,' 'VI' for 'virus,' and 'D' for disease. [...] On average, it takes five to six days from the day you are infected with SARS-CoV-2 until you develop symptoms of COVID-19. This pre-symptomatic period—also known as "incubation"—can range from one to 14 days.

From there, those with mild disease tend to recover in about two weeks, while those with more severe cases can take three to six weeks to recover, according to WHO Director-General Dr. Tedros Adhanom Ghebreyesus, who goes by Dr. Tedros.

[...] So far, some preliminary population screening for COVID-19 infections has been done in China, specifically in Guangdong province. Screening of 320,000 people who went to a fever clinic suggested that we may not be missing a vast number of mild cases. This in turn suggests that the CFRs we are calculating now are not wildly higher than they should be. However, experts still suspect that many mild cases are going unreported, and many still anticipate that the true CFR will be lower than what we are calculating now.

Coronavirus's Genetics Hint at its Cryptic Spread in Communities

Arthur T Knackerbracket has found the following story:

Hodcroft decided to generate an infographic showing the connections between the traveler from Singapore and the other coronavirus cases emerging in Europe. "I thought, I'll make an image and see if anyone else finds this useful," she says. She posted the image on Twitter, and "somewhat unexpectedly, it got a lot of attention," she says. "People were definitely really, really interested in this. So I kept that image updated over the next week or so." As she updated it, the graphic showed that at least 21 people were exposed to the virus at the ski resort the traveler from Singapore visited; 13 of those people ended up developing COVID-19, the disease caused by the virus. After she'd finished the preliminary work, a colleague of Hodcroft saw it and suggested she write it up for publication. She posted the paper on February 26; the next day it appeared in Swiss Medical Weekly.

Hodcroft talked with The Scientist about the work, how its conclusions have been supported by genetic testing of viral strains from patients, and what it tells us about the spread of the virus, SARS-CoV-2, in other countries.

The other thing that's surprising is that, according to the patient statement that he released, the focal patient never had any symptoms. In his own words, he never felt sick. So he did all of this transmission without ever having any indication that he was unwell or that he should be taking any precautions to modify his behavior. It tells us that some infections might be from people who never even know that they're sick.

A few days ago, the research group called the Seattle Flu Study, which is designed to take community samples from random people who have any kind of cough, runny nose, or cold-like symptoms and look for the flu—they pivoted and started testing some of the samples for coronavirus. They found a case in the Seattle area and sequenced the viral genome of the infected person [posted on NextStrain] and showed it links very closely with another case in the Seattle area that's from mid-January. And so this strongly suggests (though we don't yet know for certain) that there has been ongoing undetected transmission in Seattle since mid-January and wasn't picked up because we weren't looking for it. This has become clearer in the last few days, as more cases and even deaths have been reported in Washington State. That tells us the virus hasn't just appeared in the last few days in the area.

When you have a very small number of cases of a disease, you can do this just through epidemiological contact tracing: you can go to everyone and ask questions and find out the connections between the cases. As the case numbers scale up, this becomes very hard to do. With genetic sequencing, we can do this without having to go and try and figure out where everyone was at the time of infection. We've had an influx of sequences from Brazil, Switzerland, Mexico, Scotland, Germany. These have clustered with sequences from Italy and have a travel history from Italy and so from that we can show that Italy really is now exporting cases around the world to multiple countries.

One thing I would note is that studies have shown that limiting transportation really doesn't make much of an impact for outbreaks. Quarantining particular cities, if they seem to be epicenters, can work as a preventive measure, but as the epidemic scales up, you move past being able to contain it in this sense, [and] what you end up doing is just disrupting supply routes, interrupting business, making all of these things much harder.

Toilet Paper Hoarding Continues as Australia Faces Coronavirus Outbreak

Australians are still going bonkers buying up toilet paper before the coronavirus hits and some people are then selling them online for a profit. This behavior offers an intriguing insight into mob reactions of people when disaster strikes. Still staggering from horrendous bushfires and disasterous flooding, which is still ongoing, Australians now facing another immediate disaster are falling back to mob mentality copying those they see as leaders. People don't seem to understand why they are buying up toilet paper, only knowing that it is something they should do. In the meantime, stores have imposed buying limits and toilet paper heroes are keeping the paper mills running 24/7 to keep up with demand.

Just when you thought Australia could not get any stranger.

Coronavirus may tear apart Australian University that relies on Chinese students

The secondary effects of the coronavirus are being felt around the world as factory production is slower, deliveries are affected and entire countries are shut down. In Australia the University of Tasmania is cutting courses in a bid to survive foreign student loss in the midst of a travel ban imposed by Australia in a bid to slow the coming COVID19 outbreak. With UTAS (University of Tasmania) buying up tens of millions worth of real estate in prime areas for future expansion based on foreign students the future of the university may be in doubt with so many of its wealthy students unable to attend. Given expectations that the virus outbreak is expected to last months, UTAS may have to suck in its belt, reduce courses, and ride out the wave like so many other businesses facing extinction. Already several restaurants in the Sydney Chinatown area have closed due to the ongoing situation with many more predicted to come.

They could get locals to attend their local university like they did in the Old Days.

Hong Kong offers HK$10000 to stem economy free fall pushed by pandemic fears

Hong Kong government is giving out HK$10,000 to residents to stop the slide into recession. With the recent unrest from anti-China demonstrations, stoppages and finally the coronavirus outbreak, the city economy is stalled on the edge of collapse.

Time for a holiday.

Previously:
Coronavirus Breakthrough: Protein Mutation Affects Spread and Virulence of Respiratory Virus
Thailand Quarantines 32 Due to MERS Case
China Reports 3rd Death, Nearly 140 New Cases of Coronavirus
China Confirms Human-To-Human Transmission of New Coronavirus; CDC Confirms First US Case
Coronavirus: Millions Quarantined in Wuhan City
China Battles Coronavirus Outbreak: All the Latest Updates
In The Pipeline: Coronavirus
Coronavirus Declared a Global Health Emergency by World Health Organization
2019-nCoV Coronavirus Story Roundup
Australia Bans All Arrivals From China [Updated]
Novel Coronavirus (2019-nCoV) Roundup
Phishers Impersonate WHO, Exploit Coronavirus-Related Anxiety
Coronavirus Roundup
MWC Barcelona 2020: "Mobile World Congress" or "Most Won't Come"?
Coronavirus Roundup (Feb. 17)
Roundup of Stories about the SARS-CoV-2 Coronavirus and COVID-19 Disease
Coronavirus Drug Clinical Trials Beginning in Nebraska
COVID-19 (SARS-CoV-2 - CoronaVirus) Roundup
New Zealand Birds Show Humanlike Ability to Make Predictions
World Health Organization Declares the COVID-19 (Coronavirus) Outbreak a Global Pandemic


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  • (Score: 2) by HiThere on Monday March 16 2020, @03:39PM

    by HiThere (866) on Monday March 16 2020, @03:39PM (#971914) Journal

    Yeah, it makes sense. But so does the cannibalism reported of the Donner Party. Things have to be pretty bad before you make that choice.

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