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posted by martyb on Tuesday April 13 2021, @10:39PM   Printer-friendly

J&J COVID vaccine use paused due to one-in-a-million complication;:

On Tuesday morning, the Food and Drug Administration and the Centers for Disease Control and Prevention issued a release acknowledging that an extremely rare clotting disorder was associated with the use of the Johnson & Johnson COVID vaccine. The problem is actually less than a one-in-a-million issue; in data from the US, where 6.8 million doses of this vaccine have been used, there have only been six instances of the clotting problem detected.

Because the clots call for an unusual treatment, however, the organizations are calling for a pause in administering the shot. This will provide them with time to ensure the medical community is aware of the appropriate treatment.

[...] The leading hypothesis to explain the phenomenon is that, in very rare cases, the adenovirus triggers an immune response to factors found on the surface of platelets, which are an essential part of the clotting process. This activates platelets, causing clots, and at the same time reduces the total platelet count.

These seemingly contradictory changes make treating the issue through the normal approach to excessive clotting dangerous. Typically, the appearance of clots would call for using a treatment that would reduce the probability of clots forming. But due to the low platelet counts in these individuals, those treatments can make it much less likely that clots form when they're needed.

It's this difference between apparent patient needs and appropriate treatment that has caused the CDC and FDA to call for a pause in the use of the J&J vaccine.

[...] So far, all six cases have occurred among women below the age of 50 and appeared between one and two weeks after vaccination.

To put that in a different perspective, imagine giving a shot of vaccine every single second of every minute of every hour of every day.

How long would it take to reach 1 million doses? Start on the first second of a Sunday. Go through that whole day. And Monday, and Tuesday, and Wednesday, and Thursday, and Friday and Saturday — i.e. one whole week.

We're not done yet!

Add another Sunday, and Monday, and Tuesday, and Wednesday; that gets us to 11 consecutive days of non-stop dosing. That would still be less than 1 million doses. Remember this is at a rate of Jab. Jab. Jab. Jab. Non-stop.

After all that, you're still not done! You'd still need another 49,600 doses to reach exactly 1 million.


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  • (Score: 2) by nostyle on Tuesday April 13 2021, @11:43PM (17 children)

    by nostyle (11497) on Tuesday April 13 2021, @11:43PM (#1137166) Journal

    Got mine already - one and done!

    Haven't died in thirty days, and vaccine strength is now at maximum - yipee! Now I go where I please and do what I choose.

    Good luck getting yours, sucka's. Oh and watch out for stray lightning.

    --
    Waiting for the conspiracy theory explanation of all this - like maybe the Gates nanobots are malfunctioning in the J&J vax.

    Starting Score:    1  point
    Karma-Bonus Modifier   +1  

    Total Score:   2  
  • (Score: 2, Funny) by Anonymous Coward on Tuesday April 13 2021, @11:48PM (1 child)

    by Anonymous Coward on Tuesday April 13 2021, @11:48PM (#1137169)

    So how's your local 5G signal?

    • (Score: 1) by hemocyanin on Wednesday April 14 2021, @12:05AM

      by hemocyanin (186) on Wednesday April 14 2021, @12:05AM (#1137176) Journal

      <meta>Quality Troll</meta>

      Nice!

      The shame though is that isn't quite stand-alone.

  • (Score: -1, Troll) by Anonymous Coward on Tuesday April 13 2021, @11:57PM (4 children)

    by Anonymous Coward on Tuesday April 13 2021, @11:57PM (#1137173)

    Just remember to keep masking up because the vaccine doesn't do shit.

    • (Score: 0, Funny) by Anonymous Coward on Wednesday April 14 2021, @12:07AM (1 child)

      by Anonymous Coward on Wednesday April 14 2021, @12:07AM (#1137177)

      Faucist!

      • (Score: 1, Funny) by Anonymous Coward on Wednesday April 14 2021, @12:28AM

        by Anonymous Coward on Wednesday April 14 2021, @12:28AM (#1137187)

        Faucian Bargain

    • (Score: 5, Interesting) by nostyle on Wednesday April 14 2021, @12:38AM (1 child)

      by nostyle (11497) on Wednesday April 14 2021, @12:38AM (#1137193) Journal

      Just remember to keep masking up because the vaccine doesn't do shit.

      Funny, I thought _zero_ Covid hospitalizations and _zero_ Covid deaths was some pretty good $hit.

      Actually I look marvelous in a mask, and haven't had so much as a fever in 15 months, so I'm sold on wearing masks forever!!

      __
      Then, again, I'm not a woman under fifty (lucky stars maybe).

      • (Score: 2) by stretch611 on Wednesday April 14 2021, @03:36AM

        by stretch611 (6199) on Wednesday April 14 2021, @03:36AM (#1137281)

        Actually I look marvelous in a mask

        I agree, you look much better in a mask. Please continue to wear one in the interest of a better quality of life for everyone around you. :P

        --
        Now with 5 covid vaccine shots/boosters altering my DNA :P
  • (Score: 0) by Anonymous Coward on Wednesday April 14 2021, @12:16AM

    by Anonymous Coward on Wednesday April 14 2021, @12:16AM (#1137182)

    Congratulations!

    A picture is worth a thousand words.

    https://www.washingtonpost.com/politics/2021/04/13/risk-reward-calculus-johnson-johnson-vaccine-visualized/ [washingtonpost.com]

    It looks like a good thing to pass along to people you know who don't have number-oriented minds.

    The article says it's outside the WaPo's usual paywall.

  • (Score: 0) by Anonymous Coward on Wednesday April 14 2021, @12:37AM (3 children)

    by Anonymous Coward on Wednesday April 14 2021, @12:37AM (#1137192)

    "abundance of relief" because J&J vaccine is doped with oxycontin for that "extra" relief.

    • (Score: 2) by nostyle on Wednesday April 14 2021, @01:05AM (2 children)

      by nostyle (11497) on Wednesday April 14 2021, @01:05AM (#1137207) Journal

      ...vaccine is doped with oxycontin...

      Somebody once botched a surgery on my leg, leaving me with a permanent excruciating neuropathy. I spent the next three years in an oxycontin haze. Eventually my brain learned to "route around" the neuropathic sensation, and I was able to wean myself off opioids over an interval of about nine months. Been off them about six years now.

      Anyway, I am quite familiar with the feeling of being on oxycontin, and I noticed no such sensation with the J&J vaccination. I'm pretty sure you are only trolling, though.

      --
      Yes, "every little step I take" remains painful.

      • (Score: 0) by Anonymous Coward on Wednesday April 14 2021, @02:30AM (1 child)

        by Anonymous Coward on Wednesday April 14 2021, @02:30AM (#1137246)

        yo dawg, i've heard you liked oxycontin, so i gots me a box of genuine chinese-made fentanyl, all packed for shipping. send me your address and it will be sent over, pronto.

        • (Score: 0) by Anonymous Coward on Wednesday April 14 2021, @02:48AM

          by Anonymous Coward on Wednesday April 14 2021, @02:48AM (#1137261)

          Bobby Brown - is that you?

  • (Score: 0) by Anonymous Coward on Wednesday April 14 2021, @12:44AM

    by Anonymous Coward on Wednesday April 14 2021, @12:44AM (#1137196)

    "Haven't died in thirty days"

  • (Score: 2) by JoeMerchant on Wednesday April 14 2021, @01:52AM (3 children)

    by JoeMerchant (3937) on Wednesday April 14 2021, @01:52AM (#1137219)

    Good for you, not so good for the six people with potentially deadly blood clotting issues.

    Like in the early days of Polio vaccination, there is some risk in vaccinating - we tell ourselves that it's less than the risk of not vaccinating, but does everybody believe that? The real answer depends in large part on how many people end up taking the vaccines.

    --
    Україна досі не є частиною Росії Слава Україні🌻 https://news.stanford.edu/2023/02/17/will-russia-ukraine-war-end
    • (Score: 0) by Anonymous Coward on Wednesday April 14 2021, @02:11AM

      by Anonymous Coward on Wednesday April 14 2021, @02:11AM (#1137236)

      "there is some risk"

      That's life. And medicine is no different.

      Vaccination is also a public health issue, where the public policy is geared toward the larger society, not particular individuals. So, provided vaccine is low-enough risk, we encourage vaccination.

    • (Score: 1) by khallow on Wednesday April 14 2021, @04:11AM (1 child)

      by khallow (3766) Subscriber Badge on Wednesday April 14 2021, @04:11AM (#1137301) Journal

      we tell ourselves that it's less than the risk of not vaccinating, but does everybody believe that?

      Not sure where you wanted to go with that question, but it's pretty clear that the usual anti-vaxers aren't going to believe that. There will always be somebody. My take is that there's a lot more 1 in a million complications from covid than what's been talked about so far for the vaccines.

      • (Score: 2) by JoeMerchant on Wednesday April 14 2021, @01:14PM

        by JoeMerchant (3937) on Wednesday April 14 2021, @01:14PM (#1137411)

        Right now, I've read that approximately 30% of US adults are disinclined to take the COVID vaccines... I don't know what the hardline antivaxxer population slice is, I usually see it expressed in more local terms of "hotspots," one would assume that near 100% of the hardline antivaxxers are also COVID vaccine averse, but I think that 30% number includes a lot more people - which is a good thing in my opinion. I wish the vaccine debate would break down from the "ALL OR NONE" positions that are usually heard. Maybe then the establishment might focus more on transparency, clear understandable accurate independently verified and verifiable data, and letting people decide for themselves rather than attempts at intimidation through fear.

        Our kids were toddlers during the mercury removal phase for vaccines and dental fillings. It was a serious blow to the credibility of the establishment how many dentists and physicians presented the hard-line "zero risk of harm, absolutely harmless, you have nothing to worry about" position on mercury right up until it wasn't in the mainstream products anymore, and then they flip-flopped like a winning politician on election night.

        As for personal risk from not vaccinating - if 99% of the population vaccinates, then the 1% that doesn't is benefiting greatly from reduced risk of side effects and near zero risk of disease due to herd immunity. If 1% of the population vaccinates then that 1% is benefiting greatly from reduced risk of disease thanks to vaccination and the risk of side effects is negligible by comparison. In-between, somewhere there's a balance point where risk and reward are roughly equal - and at present nobody has sufficient information to assess where that balance point is. The balance point also depends greatly on whether you are regularly exposed to potentially diseased people, and in overall societal terms: whether or not at-high-risk of serious disease/death populations are exposed to you.

        In a way, it's a lot like speed limits - most places don't even post limits different for night and day, let alone weather conditions and vehicle capabilities. So, the law draws a simple conservative line in the sand and it seems that the majority of motorists cross that line the majority of the time in most conditions. Enforcement is sparse and uneven and almost wholly unrelated to safety - but good luck implementing anything more sensible.

        --
        Україна досі не є частиною Росії Слава Україні🌻 https://news.stanford.edu/2023/02/17/will-russia-ukraine-war-end