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posted by martyb on Tuesday April 13 2021, @10:39PM   Printer-friendly

J&J COVID vaccine use paused due to one-in-a-million complication;:

On Tuesday morning, the Food and Drug Administration and the Centers for Disease Control and Prevention issued a release acknowledging that an extremely rare clotting disorder was associated with the use of the Johnson & Johnson COVID vaccine. The problem is actually less than a one-in-a-million issue; in data from the US, where 6.8 million doses of this vaccine have been used, there have only been six instances of the clotting problem detected.

Because the clots call for an unusual treatment, however, the organizations are calling for a pause in administering the shot. This will provide them with time to ensure the medical community is aware of the appropriate treatment.

[...] The leading hypothesis to explain the phenomenon is that, in very rare cases, the adenovirus triggers an immune response to factors found on the surface of platelets, which are an essential part of the clotting process. This activates platelets, causing clots, and at the same time reduces the total platelet count.

These seemingly contradictory changes make treating the issue through the normal approach to excessive clotting dangerous. Typically, the appearance of clots would call for using a treatment that would reduce the probability of clots forming. But due to the low platelet counts in these individuals, those treatments can make it much less likely that clots form when they're needed.

It's this difference between apparent patient needs and appropriate treatment that has caused the CDC and FDA to call for a pause in the use of the J&J vaccine.

[...] So far, all six cases have occurred among women below the age of 50 and appeared between one and two weeks after vaccination.

To put that in a different perspective, imagine giving a shot of vaccine every single second of every minute of every hour of every day.

How long would it take to reach 1 million doses? Start on the first second of a Sunday. Go through that whole day. And Monday, and Tuesday, and Wednesday, and Thursday, and Friday and Saturday — i.e. one whole week.

We're not done yet!

Add another Sunday, and Monday, and Tuesday, and Wednesday; that gets us to 11 consecutive days of non-stop dosing. That would still be less than 1 million doses. Remember this is at a rate of Jab. Jab. Jab. Jab. Non-stop.

After all that, you're still not done! You'd still need another 49,600 doses to reach exactly 1 million.


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  • (Score: 2) by stretch611 on Wednesday April 14 2021, @03:58AM (3 children)

    by stretch611 (6199) on Wednesday April 14 2021, @03:58AM (#1137291)

    Is one in a million an accepted adverse reaction rate? How does this vaccine compare to other vaccines?

    Well, supposedly no similiar cases with moderna or pfizer vaccines.
    The Astra Zenaca vaccine had a higher rate in similar cases. Roughly 1 in 500,000 cases in Europe that last I checked the numbers. (wikipedia [wikipedia.org] does show slightly higher numbers than I thought; about 1 in 300,000.)

    Probably related... The 2 mRNA vaccines do not appear to nhave this side affect, while both the J&J and AZ vaccines have it. The latter 2 are both Viral vector vaccines [wikipedia.org] derived from a modified virus to confer immunity. (The Spunike V vaccine made in Russia is also a Viral Vector vaccine.)

    It sounds to me like the viral vector vaccines are quite similar to the actual covid virus due to the fact that blood clots are an common side effect of covid-19.
    ofc, that is why they use a similar virus to get the immunity and hopefully lesser effects. (Like cowpox being used to prevent smallpox.)

    --
    Now with 5 covid vaccine shots/boosters altering my DNA :P
    Starting Score:    1  point
    Karma-Bonus Modifier   +1  

    Total Score:   2  
  • (Score: -1, Flamebait) by Anonymous Coward on Wednesday April 14 2021, @06:23AM (2 children)

    by Anonymous Coward on Wednesday April 14 2021, @06:23AM (#1137325)

    No thnx, I'm not putting that mRNA shit in my veins. I'd prefer a REAL vaccine (sicne the fucking definition has been retconned to now include experimental shit). But in light of that, J&J seems like the least odd one of the bunch. Still, maybe I can get my hands on the Cuban vaccine, which is traditional, or I could just say FUCK IT, and not worry, since I'm not a fat fuck so my risk of dying is negligible. But i suspoect they will make some sort of vaccine mandatory so my kdis can have normal lives. Just abotu 30th mandatory vaccine on the ever icreasing list of poisoned shit. But hey, we got to keep the pharma profits flowing right?

    • (Score: 3, Interesting) by stretch611 on Wednesday April 14 2021, @07:29AM

      by stretch611 (6199) on Wednesday April 14 2021, @07:29AM (#1137345)

      Wow, you seem to be a real happy person with all of your kind words.

      I am sure that you will be happy to know that the US has already paid the big pharma companies in advance for even vaccine doses for every person in the entire US regardless of whether or not you actually use it.

      Your altruistic self sacrifice is truly remarkable in this day and age. After all, once all the vaccines are given out in the US, I am sure that the current administration will send all of the leftover doses to the poorer countries in central america. Your kindly act to not get the vaccine will inevitably mean that one of the less fortunate in those poor countries will be able to get vaccinated, saving them from the death and mayhem of coronavirus. Who knows, the poor person that you save might eventually cross the border and end up in the US only to marry your daughter. (and stay here thanks to her sacrifice to give him citizenship.)

      You are truly an inspiration to us all. If only everyone could be so kind.

      Have a BLESSED day 🥰 🥰

      --
      Now with 5 covid vaccine shots/boosters altering my DNA :P
    • (Score: 2) by Azuma Hazuki on Wednesday April 14 2021, @12:00PM

      by Azuma Hazuki (5086) on Wednesday April 14 2021, @12:00PM (#1137393) Journal

      On the upside, if you're worrying about a vaccine causing learning disabilities...well.

      --
      I am "that girl" your mother warned you about...