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An Alzheimer's Nasal Spray Vaccine Is About to Enter Human Trials For The First Time
Alzheimer's treatments seemed like an unlikely prospect mere months ago.
Drug trials tried and failed for 20 years to produce treatments that would stop the progression of the disease, and several large pharmaceutical companies abandoned the mission of developing Alzheimer's treatments altogether.
[...] Now, the field of Alzheimer's treatments may finally be opening up.
Last week, Brigham and Women's Hospital announced it would spearhead the first human trial of a nasal vaccine for Alzheimer's, designed to prevent or slow the disease's progression.
The trial is small – 16 people between ages 60 to 85 with Alzheimer's symptoms will receive two doses of the vaccine one week apart. But it builds on decades of research suggesting that stimulating the immune system can help clear out beta-amyloid plaques in the brain.
[...] The vaccine sprays a drug called Protollin directly into the nasal passage, with the goal of activating immune cells to remove the plaque.
FDA OKs Phase 1 Trial of Nasal Spray Immunotherapy Protollin
Protollin is a new intranasal immunotherapy made of proteins derived from the outer membrane of certain bacteria. It works by stimulating the innate immune system — the part of the immune system that serves as the body's first line of defense — to clear amyloid-beta plaques and tau tangles from the brain.
It worked in mice, so it must be good.
Also at Medical News Today.
Related: Novel Dementia Vaccine on Track for Human Trials Within Two Years
(Score: -1, Flamebait) by Anonymous Coward on Sunday November 28 2021, @03:52AM (2 children)
OP here, what part of my comment is "flamebait?" You think that's some "anti-vaxxer" "fake news"?
I usually don't care about modding, but this is redonculous - you (the modder) are the anti-science anti-reason loon.
(Score: 2) by The Vocal Minority on Sunday November 28 2021, @12:04PM
Sorry burned all of my mod points on the parakeet's nonsense so can't mod you back up :(
(Score: 1, Insightful) by Anonymous Coward on Sunday November 28 2021, @02:08PM
At a guess, the article claims the spray stimulates the immune system.
Per merriam webster "2: a preparation or immunotherapy that is used to stimulate the body's immune response against noninfectious substances, agents, or diseases"
While it may not fit the most widely known concept of a vaccine it still qualifies. If you're going to complain about scientific words you should do your homework. Doubly so if you're going to whine about being called out.