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Arthur T Knackerbracket has processed the following story:
Drugs developed to treat AIDS and HIV could offer hope to patients diagnosed with the most common form of primary brain tumour.
The breakthrough, co-funded by the charity Brain Tumour Research, is significant because, if further research is conclusive, the anti-retroviral drugs could be prescribed for patients diagnosed with meningioma and acoustic neuroma brain tumours (also known as schwannoma).
More effective approaches are urgently needed as there are very few treatment options for these tumour types which frequently return following surgery and radiotherapy.
Meningioma is the most common form of primary brain tumour. Mostly low-grade, it can become cancerous over time, and develops from cells located in the meninges which protect the brain and spinal cord. Acoustic neuroma is a different type of low-grade, or non-cancerous brain tumour, which develops in nerve-protecting cells called Schwann cells. Both tumours may occur spontaneously, usually in adulthood, or in the hereditary disease Neurofibromatosis type 2 (NF2) in childhood/early adolescence.
Researchers at the Brain Tumour Research Centre at the University of Plymouth have shown previously that a tumour suppressor, named Merlin, contributes to the development of meningioma, acoustic neuroma and ependymoma tumours. It can also contribute to neurofibromatosis type 2 (NF2). Tumour suppressor genes play important roles in normal cells by controlling division or repairing errors in DNA. However, when tumour suppressors do not work properly or are absent, cells can grow out of control, leading to cancer.
In this latest study Dr Sylwia Ammoun, Senior Research Fellow, and her collaborator, Dr Robert Belshaw investigated the role that specific sections of our DNA play in tumour development. Named 'endogenous retrovirus HERV-K', these sections of DNA are relics of ancient infections that affected our primate ancestors, which have become stable elements of human DNA.
(Score: 1, Troll) by Runaway1956 on Tuesday December 21 2021, @08:57PM (21 children)
Am I to understand that sometimes a drug might have beneficial side effects, that should maybe be explored and researched? Wow. Imagine that. Ivermectin, hydroxychoroquine, anti-malarial drugs, and maybe others might be useful for some things that no one imagined when they were new? Who'da thunk it?
Apparently, there aren't any brain tumor vaxes or drugs profits being threatened by repurposing HIV drugs.
Abortion is the number one killed of children in the United States.
(Score: -1, Disagree) by Anonymous Coward on Tuesday December 21 2021, @09:17PM (1 child)
Hey, all you people down-modding Runaway's comment:
You are BAD people.
You have FAILED to love the Truth.
And you will be punished.
Off-label uses have been around for DECADES, and are still in use today.
If it cannot be questioned, it is NOT SCIENCE! It's RELIGION!
(Score: 2) by Runaway1956 on Tuesday December 21 2021, @09:45PM
To be fair, I only see a disagree mod at this point in time. Which is cool. Reasonable people often disagree. But, don't worry, someone will soon be triggered by my comment, and call me a troll.
Abortion is the number one killed of children in the United States.
(Score: 5, Informative) by Anonymous Coward on Tuesday December 21 2021, @09:56PM (4 children)
That is right, they might. Too bad that they have already checked Ivermectin, Plaquenil, anti-Malarial drugs, and others and found them not to be useful for treating Coronavirus infections in populations without parasitic coinfection.
Unless you are trying to tell us you have worms. Just so you know, you can treat that before getting COVID-19.
(Score: 0) by Anonymous Coward on Tuesday December 21 2021, @10:02PM (2 children)
I guess Joe Rogan had worms, huh?
And his Medical Doctor thought he had worms, huh?
Now if only there was a pill to cure MASS MEDIA BRAINWASHING!
(Score: 2, Informative) by Anonymous Coward on Wednesday December 22 2021, @12:06AM
Never heard of 'im.
Well, I don't know that. Is that what he thought this Joe fella had? Do you have any proof at all of what this particular MD thought on this subject, and do you happen to have a sworn statement handy to back it up?
There is, it's called not watching or paying attention to the mass media, and I don't so I guess an ounce of prevention is worth a pound of cure.
That being said, Covid is a thing, it does kill people, the vaccine does it's job as advertised and you should get it if you haven't yet. And I say that as someone who knows a handful of people who caught it, none of whom considered it worse than 'a touch of the sniffles', and no one I know knows anyone who's died or even been hospitalized over it.
But it's still a big deal, because personal anecdotes, like personal opinions, are worth jack shit. Facts are numbers, and numbers are the cold, hard boot of reality.
And I came to those conclusions without once involving myself with the media, be it mainstream or social. A good grounding in basic logic and critical thinking serves as one hell of a bullshit detector.
(Score: 2, Insightful) by Anonymous Coward on Wednesday December 22 2021, @08:27AM
The error bars on an unblinded trial like that with a sample size of one eats any possibility of having evidence.
And you'll find people that will sell anything for the right amount of money.
Now if only there was a pill to cure ALT-"MEDIA" BRAINWASHING!
(Score: 2, Touché) by Anonymous Coward on Tuesday December 21 2021, @10:53PM
When the President of the United States had COVIDS, the best doctors in the nation gave him cocktails. The rest of us get a vax and a cheap beer.
(Score: 2) by DannyB on Wednesday December 22 2021, @03:56PM (13 children)
Ah, so don't rush to use it if it is not approved for such a use? If this view is shared by anti-vaxers, then I see something quite hypocritical here. (eg, the vax was rushed, etc)
You mean like a couple different drugs suddenly being discovered to have a side effect of causing erections? And then getting approved for and marketed for such use. And making way WAY WAY more money than they made for their original use.
If they were useful for this, there is some mechanism of action. For example, it is pretty obvious once you consider it how vasodilator drugs could cause erections. It is not magic or mystical. Medical experts declare that the drugs you suggest are not helpful for treating covid-19 (which I assume you are hinting at). Shirley those experts know something about the actual mechanism of action of these drugs. How they work in the body of humans and animals -- something well researched. How it would or would not affect certain conditions, such as covid-19. Also how powerful placebo effect really is. Especially combined with how powerful FOX News misinformation is.
If HIV drugs are good for brain tumors, then I would assume the brain tumor experts would see the obvious reason why this might be so.
There are doctors and scientists. And then there are MBAs chasing prophets.
I take a drug for off label use:
If you eat an entire cake without cutting it, you technically only had one piece.
(Score: 2, Disagree) by Runaway1956 on Wednesday December 22 2021, @05:16PM (12 children)
That's all rather humorous, once we consider how you attack medical people who actually want to research and experiment with said drugs. Think I'll go look at my recent journal, where a world renowned brain surgeon suggests that we have methods available to address the pandemic, which we are not using.
Abortion is the number one killed of children in the United States.
(Score: 3, Informative) by DannyB on Wednesday December 22 2021, @05:41PM (6 children)
Do all the research you want with Ivermectin, etc. If you come up with an actual reproducible result relevant to covid-19 the researchers will be famous for outsmarting all of the current experts who say this is quack medicine.
I'm not stopping anyone from researching.
If you eat an entire cake without cutting it, you technically only had one piece.
(Score: 2) by Runaway1956 on Wednesday December 22 2021, @05:53PM (5 children)
Do you remember the cocktails served to President Trump by America's best of the best doctors when he had COVID?
Abortion is the number one killed of children in the United States.
(Score: 3, Informative) by DannyB on Wednesday December 22 2021, @06:18PM
I do remember.
Do we know if they actually did any good?
A sample size of one.
I'm not saying people shouldn't do research. If there is a reproducible result, that would be good news indeed.
But experts who presumably know the mechanism of action call it quack medicine.
I'm sure Trump could get whatever treatment he wanted, whether it has any effect or not.
If you eat an entire cake without cutting it, you technically only had one piece.
(Score: 2) by DannyB on Wednesday December 22 2021, @06:24PM
Something else. I just now read in the news.
Pfizer pill becomes 1st US-authorized home COVID treatment.
This one has scientific results behind it. But some people will make it about politics instead of science and medicine.
If you eat an entire cake without cutting it, you technically only had one piece.
(Score: 2, Informative) by Anonymous Coward on Thursday December 23 2021, @01:57AM (2 children)
According to the White House, Trump received: Dexamethasone (steroid), Remdesivir (anti-viral), Casirivimab+imdevimab (monoclonal antibodies), Famotidine (antacid), Melatonin (sleep aid and diabetic comorbidity prophylaxis), and Aspirin (analgesic and blood thinner).
No Ivermectin, or Hydroxychloroquine, or other quackery in there. Turns out once the air hunger hits hard, they call real doctors to do real medicine instead of the "alien sperm" doctor for snake oil.
(Score: 1) by Runaway1956 on Thursday December 23 2021, @04:20AM (1 child)
You've done nicely there. Now, how many of those drugs are commonly available to common citizens?
Abortion is the number one killed of children in the United States.
(Score: 1, Informative) by Anonymous Coward on Thursday December 23 2021, @08:11AM
Dexamethasone (steroid), Remdesivir (anti-viral), Casirivimab+imdevimab (monoclonal antibodies), Famotidine (antacid), Melatonin (sleep aid and diabetic comorbidity prophylaxis), and Aspirin (analgesic and blood thinner).
All of them are and three of them are in your pharmacy right now. You may even have them in your medicine cabinet now and not even know it.
(Score: 2, Troll) by aristarchus on Wednesday December 22 2021, @09:18PM (4 children)
World renowned looney, who thinks the pyramids in Egypt were used as granaries. Yes, by all means, go look at your own journal of misinformation, Runaway! It boggles my mind that you have a family that cares enough about you to get you vaxxed, even while you are sucking down the horsey medicine. (And, you should equally ref the crazy French doc who "studied" Trump's Chloroxyhydrophoquinine! Didier Raoult, who declared the pandemic over in May of 2020. )
No one is fooled by your alt-right-meds whataboutism, you ignorant moron, Runaway!
(Score: 2) by Runaway1956 on Wednesday December 22 2021, @09:24PM (3 children)
Your alleged mind has been boggled since you hatched.
Abortion is the number one killed of children in the United States.
(Score: 1, Troll) by aristarchus on Wednesday December 22 2021, @09:42PM (2 children)
You never told us, did they hogtie you for the booster, yet? Omicron is coming, Runaway!
(Score: 2) by Runaway1956 on Wednesday December 22 2021, @10:16PM (1 child)
I've put an armor plate door on my computer room, with a PoE cameras showing me what's outside the door, and a .50 cal machine gun poking through the door. They won't have an easy time of it next time around!
Abortion is the number one killed of children in the United States.
(Score: 2) by aristarchus on Thursday December 23 2021, @10:05PM
In a double-wide, does no good to armor plate the door, since the walls are made of thin wood paneling and some foam or fiberglass insulation.
(Score: -1, Offtopic) by Anonymous Coward on Tuesday December 21 2021, @10:06PM (6 children)
During one of the FDA-Pfizer approval meetings, the CEO of Pfizer got asked if he knew what happens when the vaccine mRNA gets into a cell expressing HIV or HERV-K.
The CEO just burst out laughing in his face and said no one has checked that.
(Score: 3, Touché) by Anonymous Coward on Wednesday December 22 2021, @12:12AM (4 children)
You didn't provide a source for that amusing attempt at a joke, probably because it never happened.
The reason I'm betting on it being bullshit, is that the mRNA vaccines being deployed against covid are only possible because the technology was already being developed for use against, you guessed it, HIV [cnbc.com].
The tech originally developed for use on HIV, has never had it's effects checked on HIV? Riiight... now tell me the one about the billionaire who's been bankrupt more times than I've purchased a vehicle, and why that means he's a good businessman who knows how things work and is qualified to lead a country. That ones a real thighslapper.
(Score: 0) by Anonymous Coward on Wednesday December 22 2021, @02:50AM (3 children)
It was before the approval. They are all 8 hrs long and I'm not rewatching it. You can if you want:
https://m.youtube.com/watch?v=1XTiL9rUpkg [youtube.com]
https://m.youtube.com/watch?v=tG7CzK5JZYM [youtube.com]
One of these but maybe there was another meeting in there. I believe it was the second one they had.
(Score: 0) by Anonymous Coward on Wednesday December 22 2021, @08:37AM (2 children)
LOL. The CEO of Pfizer isn't in either of those videos.
(Score: 0) by Anonymous Coward on Wednesday December 22 2021, @09:07AM
If so, then it is a different one. The guy asking eventually voted against approval for 16-17 year olds.
(Score: -1, Troll) by Mockingbird on Thursday December 23 2021, @08:18PM
He must be in the Project Veritas video. Experts said deepfakes are going to be a problem.
(Score: 0) by Anonymous Coward on Thursday December 23 2021, @02:02AM
That never happened because asking that question in that situation is so stupid on so many levels that I would feel embarrassed for the questioner. Although if I were the CEO and someone asked me that question at an FDA meeting, I'd probably laugh in their face reflexively as well precisely because it is so stupid.