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posted by janrinok on Friday December 26 2014, @12:27PM   Printer-friendly
from the dem-bones-dem-bones-dem-dry-bones dept.

Nicholas St. Fluer reports at The Atlantic that according to researchers, our convenient, sedentary way of life is making our bones weak foretelling a future with increasing fractures, breaks, and osteoporosis. For thousands of years, hunter-gatherers trekked on strenuous ventures for food with dense skeletons supporting their movements and a new study pinpoints the origin of weaker bones at the beginning of the Holocene epoch roughly 12,000 years ago, when humans began adopting agriculture. “Modern human skeletons have shifted quite recently towards lighter—more fragile, if you like—bodies. It started when we adopted agriculture. Our diets changed. Our levels of activity changed,” says Habiba Chirchir, A second study attributes joint bone weakness to different levels of physical activity in ancient human societies, also related to hunting versus farming.

The team scanned circular cross-sections of seven bones in the upper and lower limb joints in chimpanzees, Bornean orangutans and baboons. They also scanned the same bones in modern and early modern humans as well as Neanderthals, Paranthropus robustus, Australopithecus africanus and other Australopithecines. They then measured the amount of white bone in the scans against the total area to find the trabecular bone density. Crunching the numbers confirmed their visual suspicions. Modern humans had 50 to 75 percent less dense trabecular bone than chimpanzees, and some hominins had bones that were twice as dense compared to those in modern humans. Both studies have implications for modern human health and the importance of physical activity to bone strength. “The lightly-built skeleton of modern humans has a direct and important impact on bone strength and stiffness,” says Tim Ryan. That's because lightness can translate to weakness—more broken bones and a higher incidence of osteoporosis and age-related bone loss. The researchers warn that with the desk-bound lives that many people lead today, our bones may have become even more brittle than ever before. “We are not challenging our bones with enough loading," says Colin Shaw, "predisposing us to have weaker bones so that, as we age, situations arise where bones are breaking when, previously, they would not have."

 
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  • (Score: 5, Interesting) by Joe on Friday December 26 2014, @05:35PM

    by Joe (2583) on Friday December 26 2014, @05:35PM (#129300)

    Bone remodeling is done by two main cell types - osteoblasts that make bone and osteoclasts that break bone down. The balance of the numbers/activity of these cells determines bone density and are regulated by stress and calcium needs.

    Maybe we just have weaker bones do to less activity as the summary says.
    Or maybe:
    Bone remodeling is resource intensive process that happening constantly and those resources were better spent elsewhere with a change in lifestyle.
    Our immune system became a higher priority which resulted in more myeloid cells and, in turn, osteoclasts.
    We had a greater need for the immunomodulatory functions of mesenchymal stem cells (the progenitor of osteoblasts) or they differentiated into fat or cartilage cells instead - less osteoblasts

    I don't know what the reason is, but it would be interesting to know what process actually drove the change in bone density and if there were any physiological changes that resulted from it.

    - Joe

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