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Best movie second sequel:

  • The Empire Strikes Back
  • Rocky II
  • The Godfather, Part II
  • Jaws 2
  • Star Trek II: The Wrath of Khan
  • Superman II
  • Godzilla Raids Again
  • Other (please specify in comments)

[ Results | Polls ]
Comments:90 | Votes:153

posted by janrinok on Saturday November 27 2021, @09:26PM   Printer-friendly
from the helping-hand-is-healthy dept.

Giving social support to others may boost your health:

While researchers have long thought that receiving social support from others is a key to health, results from studies have shown mixed results. So researchers from The Ohio State University decided to see if giving support may also play an important role in health.

They found that on one important measure of health -- chronic inflammation -- indicators of positive social relationships were associated with lower inflammation only among people who said they were available to provide social support to family and friends.

In other words, having friends to lean on may not help your health unless you also say that you're available to help them when they need it.

“Positive relationships may be associated with lower inflammation only for those who believe they can give more support in those relationships,” said Tao Jiang, lead author of the study and a doctoral student in psychology at Ohio State.

Preliminary evidence in the study suggested that the link between health and the willingness to help others may be especially important for women.

[...] The study used data from 1,054 participants in the National Survey of Midlife Development in the U.S. These were all healthy adults between 34 and 84 years old.

Journal Reference:
Tao Jiang, Syamil Yakin, Jennifer Crocker, Baldwin M. Way. Perceived social support-giving moderates the association between social relationships and interleukin-6 levels in blood. Brain, Behavior, and Immunity, 2022; 100: 25 (DOI: 10.1016/j.bbi.2021.11.002)


Original Submission

posted by janrinok on Saturday November 27 2021, @03:47PM   Printer-friendly

Researchers reveal how to turn a global warming liability into a profitable food security solution:

“Industrial sources in the U.S. are emitting a truly staggering amount of methane, which is uneconomical to capture and use with current applications,” said study lead author Sahar El Abbadi, who conducted the research as a graduate student in civil and environmental engineering.

"Our goal is to flip that paradigm, using biotechnology to create a high-value product," added El Abbadi, who is now a lecturer in the Civic, Liberal and Global Education program at Stanford.

[...] Although carbon dioxide is more abundant in the atmosphere, methane's global warming potential is about 85 times as great over a 20-year period and at least 25 times as great a century after its release. Methane also threatens air quality by increasing the concentration of tropospheric ozone, exposure to which causes an estimated 1 million premature deaths annually worldwide due to respiratory illnesses. Methane's relative concentration has grown more than twice as fast as that of carbon dioxide since the beginning of the Industrial Revolution due in great part to human-driven emissions.

A potential solution lies in methane-consuming bacteria called methanotrophs. These bacteria can be grown in a chilled, water-filled bioreactor fed pressurized methane, oxygen and nutrients such as nitrogen, phosphorus and trace metals. The protein-rich biomass that results can be used as fishmeal in aquaculture feed, offsetting demand for fishmeal made from small fish or plant-based feeds that require land, water and fertilizer.

“While some companies are doing this already with pipeline natural gas as feedstock, a preferable feedstock would be methane emitted at large landfills, wastewater treatment plants and oil and gas facilities,” said study co-author Craig Criddle, a professor of civil and environmental engineering in Stanford’s School of Engineering. “This would result in multiple benefits [...] including lower levels of a potent greenhouse gas in the atmosphere, more stable ecosystems and positive financial outcomes.”

Consumption of seafood, an important global source of protein and micronutrients, has increased more than fourfold since 1960. As a result, wild fish stocks are badly depleted, and fish farms now provide about half of all the animal-sourced seafood we eat. The challenge will only grow as global demand for aquatic animals, plants and algae will likely double by 2050, according to a comprehensive review of the sector led by researchers at Stanford and other institutions.


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posted by janrinok on Saturday November 27 2021, @11:02AM   Printer-friendly
from the constant-mutable dept.

From Nature

Researchers in South Africa are racing to track the concerning rise of a new variant of the coronavirus that causes COVID-19. The variant harbours a large number of mutations found in other variants, including Delta, and it seems to be spreading quickly across South Africa.

A top priority is to track the variant more closely as it spreads: it was first identified in Botswana this month and has turned up in travellers to Hong Kong from South Africa. Scientists are also trying to understand the variant's properties, such as whether it can evade immune responses triggered by vaccines and whether it causes more or less severe disease than other variants do.

WHO calls special meeting to discuss new Covid variant found in South Africa with 'a large number of mutations':

The World Health Organization is monitoring a new variant with numerous mutations to the spike protein, scheduling a special meeting Friday to discuss what it may mean for vaccines and treatments, officials said Thursday.

Journal Reference:
Ewen Callaway. Heavily mutated coronavirus variant puts scientists on alert, (DOI: 10.1038/d41586-021-03552-w)

Editor's Note: The UK, France and some Asian countries have suspended flights from 6 African countries as from 26 Nov at the time of processing this story Other countries may choose to do the same.


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posted by janrinok on Saturday November 27 2021, @06:17AM   Printer-friendly

SpaceX's Starlink Will Make Life Hell for Astronomers Like Me. Telescopes on the Moon Could Help Fix That.:

This "mega-constellation" of Starlink satellites is the brainchild of Elon Musk's company SpaceX. Their plan is something straight out of science fiction: put 42,000 satellites into orbit, and broadcast wireless internet to anyone and everyone, all of the time. Early reviews have been... less than stellar ("unreliable, inconsistent, and foiled by even the merest suggestion of trees", said The Verge). But the tech will no doubt improve. Like it or not, ubiquitous Starlink internet is coming.

There's also no reason to think that SpaceX is the only player in town. A number of other companies and countries are all planning their own satellite mega-constellations, from Amazon (3,236 satellites as part of Project Kuiper), OneWeb, and Boeing, to China's ambitious plan for a 13,000-strong swarm.

Astronomers like myself have been less than enthusiastic about the prospect of a night sky full of artificial satellites. Our most sensitive telescopes are designed to pick up the unimaginably faint signals from planets orbiting distant stars, and galaxies billions of years in the past. How did the first galaxies form after the Big Bang? How fast is the universe expanding? Are there any dangerous asteroids that might crash into Earth? Having tens of thousands of satellites criss-crossing the sky and obscuring the view is going to make answering these questions more difficult.

This is going to be a serious problem for some future projects. The Vera C. Rubin Observatory is an upcoming telescope, located under Chile's dark skies, that will have the unprecedented ability to photograph the entire sky every few nights.

[...] It will also be severely impacted by satellite constellations. The telescope is sensitive enough to observe some of the faintest visible signals imaginable, with an extremely wide view of the sky. But that also means that satellite trails that cross its view show up as awful wide streaks that ruin the image. Up to a third of all the data taken by the telescope could be seriously affected, hampering its ability to study everything from near-Earth asteroids to the distant universe.

SpaceX has made some effort to dim their satellites—but even the new black-painted versions, called DarkSat, are still pretty bright (they "do not achieve the brightness goals recommended," according to the International Astronomical Union). And even if SpaceX plays nice with astronomers, the orbital gold-rush is only just getting started. We could have more than 100,000 satellites in orbit around Earth within the next 10 years.

[...] This is a tragedy: The sight of our universe, in all its splendor, is nothing less than a shared human birthright. But there are other worlds, and other skies. And the clearest, most pristine sky of all is waiting for us on the silent surface of the moon. We just need to take that one small step.


Original Submission

posted by martyb on Saturday November 27 2021, @01:32AM   Printer-friendly
from the hard-work-pays-off dept.

New Ultrahard Diamond Glass Synthesized

Carnegie's Yingwei Fei and Lin Wang were part of an international research team that synthesized a new ultrahard form of carbon glass with a wealth of potential practical applications for devices and electronics. It is the hardest known glass with the highest thermal conductivity among all glass materials. Their findings are published in Nature.

[...] Because of its extremely high melting point, it's impossible to use diamond as the starting point to synthesize diamond-like glass. However, the research team, led by Jilin University's Bingbing Liu and Mingguang Yao—a former Carnegie visiting scholar—made their breakthrough by using a form of carbon composed of 60 molecules arranged to form a hollow ball. Informally called a buckyball, this Nobel Prize-winning material was heated just enough to collapse its soccer-ball-like structure to induce disorder before turning the carbon to crystalline diamond under pressure.

The team used a large-volume multi-anvil press to synthesize the diamond-like glass. The glass is sufficient large for characterization. Its properties were confirmed using a variety of advanced, high-resolution techniques for probing atomic structure.

Journal Reference:
Yuchen Shang, Zhaodong Liu, Jiajun Dong, et al. Ultrahard bulk amorphous carbon from collapsed fullerene, Nature (DOI: 10.1038/s41586-021-03882-9)


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posted by janrinok on Friday November 26 2021, @08:45PM   Printer-friendly
from the underused-nexus! dept.

Ars Technica has a series-recap-thing going on for "The Wheel of Time" series on Amazon: https://arstechnica.com/gaming/2021/11/two-book-readers-recap-the-first-three-episodes-of-amazons-the-wheel-of-time/

In the event that you dislike people ruining great books for stupid political agendas, perhaps you should steer clear of this review of Amazon's TV Series.

These recaps won't cover every element of every episode, but they will contain major spoilers for the show and the book series. If you want to stay unspoiled and haven't read the books, these recaps aren't for you.

#1 The way magic works in the Wheel of Time (WoT) is crucial to the plot of the entire series. This is ignored entirely in the first three episodes. Which makes me think, they're going to be doing even more stupid things.
#2 Being inclusive and trying to say, but the girls should also be included as possible main plot "Dragon Reborn" hype is stupid. Egwene goes from village girl to badass quite well on her own in the books, thank you very much.
#3 Lan in the first few episodes sucks. In the books, he can take a few dozen trollocs on his own. Whereas in the first few episodes, Moiraine is barely able to take down a nice grouped up bunch? That is stupid beyond words. (We will gloss over the deliberate destruction of the town's property, because apparently it's easier to throw bricks.)
#4 Mat is a thief and his parents are evil, essentially. His Mom is a drunk, apparently driven to it by his Dad who is shown as unfaithful and essentially a deadbeat.
#5 There is a lot of sexing going on. This is a long ways away from Perrin and his lady falling down the stairs on top of each other and being embarassed.
#6 Where is Elyas?

This is no faithful adaptation from the books. In the event that you happened to like "The Lion, the Witch, and the Wardrobe", but were put off by "The Silver Chair", because they turned Peter into a whiny brat... you will be even more put off by the random stupid changes they made in this book. Rand wasn't always a brooding semi-sociopath and Mat is a lot more honorable than portrayed by these first few episodes.

[...] Probably the most annoying things to me are the twisting of characters and plot to make them more "woke". Like, if they'd added a scene in Lord of the Rings where someone asks, if Frodo and Samwise are gay. You know, because they are traveling together, so you must be gay. What kind of stupid?


Original Submission

posted by janrinok on Friday November 26 2021, @03:51PM   Printer-friendly
from the femurs-for-Algernon dept.

A Stunning 3D Map of Blood Vessels and Cells in a Mouse Skull Could Help Scientists Make New Bones:

"We need to see what's happening inside the skull, including the relative locations of blood vessels and cells and how their organization changes during injury and over time," says Warren Grayson, Ph.D., professor of biomedical engineering and director of the Laboratory for Craniofacial and Orthopaedic Tissue Engineering at the Johns Hopkins University School of Medicine. His lab focuses on developing biomaterials and transplanting stem cells into the skull to re-create missing bone tissue.

Other scientists have provided maps of small portions of blood vessels and stem cells in the mouse skull. "However, a larger picture of the skull gives us a better understanding of the entire vasculature and distribution of different stem cell types," says Alexandra Rindone, graduate student at The Johns Hopkins University and School of Medicine and first author of the paper.

The new map, published Oct. 28 in Nature Communications, is a 3D view of the top of a mouse skull -- its cranial bone, or calvaria -- which is made up of four connected skull bones.

To create the map, which includes hundreds of thousands of cells, the Johns Hopkins researchers used four key techniques to pinpoint vessels and cells.

First, they used immunofluorescence to tag molecules on the surface of a variety of blood vessels and stem cells with a fluorescent, or glowing, chemical.

Then, the scientists use a chemical compound that helps light penetrate the skull without scattering -- a method called optical tissue clearing. "It makes the skull appear like glass," says Rindone.

Video of 3D map of mouse skull: https://www.youtube.com/watch?v=VGNdBcHNo7E

Journal Reference:
Alexandra N. Rindone, Xiaonan Liu, Stephanie Farhat, et al. Quantitative 3D imaging of the cranial microvascular environment at single-cell resolution [open], Nature Communications (DOI: 10.1038/s41467-021-26455-w)


Original Submission

posted by janrinok on Friday November 26 2021, @11:34AM   Printer-friendly
from the just-long-enough-for-a-good-sleep dept.

One year on this giant, blistering hot planet is just 16 hours long:

The hunt for planets beyond our solar system has turned up more than 4,000 far-flung worlds, orbiting stars thousands of  light years from Earth. These extrasolar planets are a veritable menagerie, from rocky super-Earths and miniature Neptunes to colossal gas giants.

Among the more confounding planets discovered to date are "hot Jupiters" —  massive balls of gas that are about the size of our own Jovian planet but that zing around their stars in less than 10 days, in contrast to Jupiter's plodding, 12-year orbit. Scientists have discovered about 400 hot Jupiters to date. But exactly how these weighty whirlers came to be remains one of the biggest unsolved mysteries in planetary science.

Now, astronomers have discovered one of the most extreme ultrahot Jupiters  — a gas giant that is about five times Jupiter's mass and blitzes around its star in just 16 hours. The planet's orbit is the shortest of any known gas giant to date.

Due to its extremely tight orbit and proximity to its star, the planet's day side is estimated to be at around 3,500 Kelvin, or close to 6,000 degrees Fahrenheit — about as hot as a small star. This makes the planet, designated TOI-2109b, the second hottest detected so far.

Judging from its properties, astronomers believe that TOI-2109b is in the process of "orbital decay," or spiraling into its star, like bathwater circling the drain. Its extremely short orbit is predicted to cause the planet to spiral toward its star faster than other hot Jupiters.

The discovery, which was made initially by NASA's Transiting Exoplanet Survey Satellite (TESS), an MIT-led mission, presents a unique opportunity for astronomers to study how planets behave as they are drawn in and swallowed by their star.

"In one or two years, if we are lucky, we may be able to detect how the planet moves closer to its star," says Ian Wong, lead author of the discovery, who was a postdoc at MIT during the study and has since moved to NASA Goddard Space Flight Center. "In our lifetime we will not see the planet fall into its star. But give it another 10 million years, and this planet might not be there."

Journal Reference:
Ian Wong, Avi Shporer, George Zhou, et al. TOI-2109: An Ultrahot Gas Giant on a 16 hr Orbit - IOPscience, The Astronomical Journal [open] (DOI: https://iopscience.iop.org/article/10.3847/1538-3881/ac26bd)


Original Submission

posted by janrinok on Friday November 26 2021, @06:48AM   Printer-friendly
from the beats'-bad-business-barriers-beaten-back-by-big-beatdown dept.

Italy fines Amazon, Apple $230M over reseller collusion – TechCrunch:

Amazon and Apple have been hit with almost $230 million (€203M) in total fines by Italy’s antitrust authority — following an investigation into reselling of Apple and (Apple-owned) Beats kit on Amazon’s Italian ecommerce marketplace.

The authority says the alleged collusion decreased the level of discounts available to consumers buying Apple and Beats products on the Amazon Italy marketplace.

It has also ordered the tech giants to end the restrictions on resellers.

The AGCM announced the sanction today, saying its probe identified a restrictive agreement between the pair to block some “legitimate” resellers of Beats products on Amazon.it.

The fine breaks down into €134.5M (~$151M) for Amazon — and €68.7M (~$77.3M) for Apple.

The agreement in question was signed between the pair back in October 2018.

Per the AGCM’s press release, it found the agreement contained a number of contractual clauses which prohibited official and unofficial resellers of Apple and Beats products from using Amazon.it — with the restriction limiting the sale of Apple and Beats products on Amazon.it to Amazon itself and a number of resellers the authority says were “chosen individually and in a discriminatory way” — in violation of Art. 101 of the Treaty on the Functioning of the European Union.


Original Submission

posted by janrinok on Friday November 26 2021, @02:03AM   Printer-friendly

Samsung Officially Announces $17 Billion Advanced Semiconductor Site in Texas – Facility to Span More Than 5 Million Square Meters

After multiple reports and of course, surveying various locations in the U.S., Samsung has officially announced that Taylor, Texas[*], is the location of the Korean giant's $17 billion advanced chip manufacturing facility. The company states that the new hub will boost production of various semiconductor solutions that will be found in next-generation solutions, including smartphones.

[...] The Korean tech behemoth says that groundbreaking will begin in the first half of 2022, with operations expected to start in the second half of 2024. Unfortunately, this timeline means that this chip manufacturing hub will not be one of the locations where Samsung will mass produce its 3nm wafers, as a previous report states that mass production of this advanced process will commence in the first half of 2022.

[*] Taylor, Texas on Wikipedia.

Texas To Get Multiple New Fabs as Samsung and TI to Spend $47 Billion on New Facilities

After a year of searching for the right place of its new U.S. fab, Samsung this week announced that it would build a fab near Taylor, Texas. The company will invest $17 billion in the new semiconductor fabrication plant and will receive hundreds of millions of dollars in incentives from local and state authorities. Separately, Texas authorities have announced that Texas Instruments intend to spend $30 billion on new fabs in the state, as well.

[...] The Governor of Texas recently announced the Texas Instruments was planning to build several new 300-mm fabs near Sherman[**]. In total, TI intends to build as many as four wafer fabrication facilities in the region over coming decades and the cumulative investments are expected to total $30 billion as fabs will be eventually upgraded.

Texas Instruments itself [has] yet have to formally announce its investments plans, but the announcement by the governor Greg Abbot indicates that the principal decisions have been made and now TI needs to finalize the details.

[**] Sherman, Texas on Wikipedia.


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posted by chromas on Thursday November 25 2021, @09:12PM   Printer-friendly
from the how-many-of-these-do-you-recognize? dept.

Retrotechtacular: Office Equipment From The 1940s:

If you can’t imagine writing a letter on a typewriter and putting it in a mailbox, then you take computers for granted. But that’s just the tip of the iceberg. More niche applications begat niche machines, and a number of them are on display in this film that the Computer History Archives Project released last month. Aside from the File-o-matic Desk, the Addressograph, or the Sound Scriber, there a number of other devices that give us a peek into a bygone era.

YouTube has a 17m00s video by IBM demonstrating many of these in use.


Original Submission

posted by chromas on Thursday November 25 2021, @04:32PM   Printer-friendly

https://www.os2museum.com/wp/the-secret-history-of-atapi/

The other day I asked myself a seemingly trivial question: What was the first ATAPI CD-ROM drive and when was it available? Given that ATAPI was a major technology which instantly obsoleted all proprietary CD-ROM interfaces and made SCSI much less desirable, one might expect that there would have been some press releases touting the advantages of the new technology, articles describing the whys and wherefores, but… nope. There is nothing.

In 1993, CD-ROM drives used either SCSI or one of several proprietary interfaces, the major amongst those being Matsushita/Panasonic, Mitsumi, Philips, and Sony. In 1995, the proprietary interfaces were effectively gone and most new CD-ROM drives used the ATAPI interface. Something clearly happened in 1994, but exactly what, when, and how—that’s something of a mystery.

[Ed. note: As one who was around when this happened, I found it to be a detailed and fascinating read! Unfortunately, it was years later when I could afford my first CD-ROM. Who else here has experience from those early days? --martyb]


Original Submission

posted by janrinok on Thursday November 25 2021, @11:55AM   Printer-friendly
from the Pew!-Pew!-Pew! dept.

Ultrashort-pulse lasers kill bacterial superbugs, spores:

Life-threatening bacteria are becoming ever more resistant to antibiotics, making the search for alternatives to antibiotics an increasingly urgent challenge. For certain applications, one alternative may be a special type of laser.

Researchers at Washington University School of Medicine in St. Louis have found that lasers that emit ultrashort pulses of light can kill multidrug-resistant bacteria and hardy bacterial spores. The findings, available online in the Journal of Biophotonics, open up the possibility of using such lasers to destroy bacteria that are hard to kill by other means. The researchers previously have shown that such lasers don't damage human cells, making it possible to envision using the lasers to sterilize wounds or disinfect blood products.

"The ultrashort-pulse laser technology uniquely inactivates pathogens while preserving human proteins and cells," said first author Shaw-Wei (David) Tsen, MD, PhD, an instructor of radiology at Washington University's Mallinckrodt Institute of Radiology (MIR). "Imagine if, prior to closing a surgical wound, we could scan a laser beam across the site and further reduce the chances of infection. I can see this technology being used soon to disinfect biological products in vitro, and even to treat bloodstream infections in the future by putting patients on dialysis and passing the blood through a laser treatment device."

Tsen and senior author Samuel Achilefu, PhD, the Michel M. Ter-Pogossian Professor of Radiology and director of MIR's Biophotonics Research Center, have been exploring the germicidal properties of ultrashort-pulse lasers for years. They have shown that such lasers can inactivate viruses and ordinary bacteria without harming human cells. In the new study, conducted in collaboration with Shelley Haydel, PhD, a professor of microbiology at Arizona State University, they extended their exploration to antibiotic-resistant bacteria and bacterial spores.

The researchers trained their lasers on multidrug-resistant Staphylococcus aureus (MRSA), which causes infections of the skin, lungs and other organs, and extended spectrum beta-lactamase-producing Escherichia coli (E. coli), which cause urinary tract infections, diarrhea and wound infections. Apart from their shared ability to make people miserable, MRSA and E. coli are very different types of bacteria, representing two distant branches of the bacterial kingdom. The researchers also looked at spores of the bacterium Bacillus cereus, which causes food poisoning and food spoilage. Bacillus spores can withstand boiling and cooking.

In all cases, the lasers killed more than 99.9% of the target organisms, reducing their numbers by more than 1,000 times.

Journal Reference:
Shaw-Wei D. Tsen, John Popovich, Megan Hodges, et al. Inactivation of multidrug‐resistant bacteria and bacterial spores and generation of high‐potency bacterial vaccines using ultrashort pulsed lasers, Journal of Biophotonics (DOI: 10.1002/jbio.202100207)


Original Submission

posted by janrinok on Thursday November 25 2021, @07:08AM   Printer-friendly
from the CoCs dept.

https://github.com/rust-lang/team/pull/671

The entire moderation team resigns, effective immediately. This resignation is done in protest of the Core Team placing themselves unaccountable to anyone but themselves.

As a result of such structural unaccountability, we have been unable to enforce the Rust Code of Conduct to the standards the community expects of us and to the standards we hold ourselves to. To leave under these circumstances deeply pains us, and we apologize to all of those that we have let down. In recognition that we are out of options from the perspective of Rust Governance, we feel as though we have no course remaining to us but to step down and make this statement.

In so doing, we would offer a few suggestions to the community writ large:

  • We suggest that Rust Team Members come to a consensus on a process for oversight over the Core Team. Currently, they are answerable only to themselves, which is a property unique to them in contrast to all other Rust teams.

  • In the interest of not perpetuating unaccountability, we recommend that the replacement for the Mod Team be made by Rust Team Members not on the Core Team.
  • We suggest that the future Mod Team, with advice from Rust Team Members, proactively decide how best to handle and discover unhealthy conflict among Rust Team Members. We suggest that the Mod Team work with the Foundation in obtaining resources for professional mediation.

Original Submission

posted by janrinok on Thursday November 25 2021, @02:19AM   Printer-friendly

Chemotherapy may affect muscle cells at lower doses than previously thought: The cancer therapy may also affect the protein building process, not just cause muscles to degrade:

According to the researchers, it was previously known that chemotherapy drugs can affect the mitochondria within cells, which can cause the loss of muscle tissue via a process called oxidative stress.

In their new study, the researchers studied three different chemotherapy drugs in cultured muscle cells at levels too low to trigger oxidative stress. They found that the muscle cells were still affected by the lower levels of drugs -- this time by interfering with the process that builds muscle, called protein synthesis.

Gustavo Nader, associate professor of kinesiology, said that while the findings need to be confirmed in humans, they could have implications for cancer treatment in the future.

"Eventually, it may be that the implementation of cancer treatments should consider that even at low doses that do not cause oxidative stress, some chemotherapy drugs may still promote the loss of muscle tissue," Nader said. "The tumor is already making you weak, it's contributing to the loss of muscle mass, and the chemo drugs are helping the tumor to accomplish that."

Additionally, Nader said the results -- recently published in the American Journal of Physiology -- Cell Physiology -- also have the potential to change how health care professionals think about the ways chemotherapy affects the body.

"For a long time, people thought the problem with chemo and muscle loss was an issue with degrading the proteins that already existed in the muscle," Nader said. "So, a lot of research and treatments in the past had the goal of preventing protein degradation. But our study points to there also being a problem with protein synthesis, or the building of new muscle proteins, as well."

Nader said that in addition to having implications for chemotherapy treatment, the findings could also ultimately change the way health care professionals think about other, pharmaceutical cancer treatments and programs.

Journal Reference:
Bin Guo, Devasier Bennet, Daniel J. Belcher, et al. Chemotherapy agents reduce protein synthesis and ribosomal capacity in myotubes independent of oxidative stress, American Journal of Physiology-Cell Physiology (DOI: 10.1152/ajpcell.00116.2021)


Original Submission