| Title | Chemists Recruit Anthrax to Deliver Cancer Drugs | |
| Date | Thursday September 25 2014, @10:54PM | |
| Author | LaminatorX | |
| Topic | ||
| from the domestication dept. | ||
With some tinkering, a deadly protein becomes an efficient carrier for antibody drugs. In a paper appearing in the journal ChemBioChem, Pentelute and colleagues showed that they could use this disarmed version of the anthrax toxin to deliver two proteins known as antibody mimics, which can kill cancer cells by disrupting specific proteins inside the cells. This is the first demonstration of effective delivery of antibody mimics into cells, which could allow researchers to develop new drugs for cancer and many other diseases, says Pentelute, the senior author of the paper.
http://newsoffice.mit.edu/2014/cancer-drug-delivery-by-anthrax-0925
[Abstract]: http://onlinelibrary.wiley.com/doi/10.1002/cbic.201402290/abstract;jsessionid=32ED743FFB7BFD9BD62AC19C29E36F94.f02t02
[Paper PDF]: http://onlinelibrary.wiley.com/doi/10.1002/cbic.201402290/pdf
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