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takyon writes:

Ketamine could become an approved treatment for depression in the UK soon:

Ketamine has 'fast-acting benefits' for depression

Ketamine has "shown promise" in the rapid treatment of major depression and suicidal thoughts, a US study says. Ketamine has a reputation as a party drug but is licensed as an anaesthetic. The study found use of the drug via a nasal spray led to "significant" improvements in depressive symptoms in the first 24 hours. The Royal College of Psychiatrists said it was a "significant" study that brought the drug "a step closer to being prescribed on the NHS".

The report by researchers from Janssen Research and Development, a Johnson and Johnson company, and Yale School of Medicine, is the first study into ketamine as a treatment for depression that has been done by a drug company.

[...] The study found those using esketamine had a much greater improvement in depression symptoms at all points over the first four weeks of treatment. However, at 25 days the effects had levelled out. The study's authors suggest it could offer an effective rapid treatment for people severely depressed and at imminent risk of suicide and could help in the initial stages of treatment, as most anti-depressants take four to six weeks to become fully effective.

Also at Medical Daily.

Efficacy and Safety of Intranasal Esketamine for the Rapid Reduction of Symptoms of Depression and Suicidality in Patients at Imminent Risk for Suicide: Results of a Double-Blind, Randomized, Placebo-Controlled Study (DOI: 10.1176/appi.ajp.2018.17060720) (DX)

Can a Framework Be Established for the Safe Use of Ketamine? (DOI: 10.1176/appi.ajp.2018.18030290) (DX)

Related: FDA Designates MDMA as a "Breakthrough Therapy" for PTSD; Approves Phase 3 Trials
Study Suggests Psilocybin "Resets" the Brains of Depressed People
Ketamine Reduces Suicidal Thoughts in Depressed Patients
Studies Identify How Ketamine Can Reverse Symptoms of Depression
Over Years, Depression Changes the Brain, new Study Shows

Original Submission

1. "takyon" - https://soylentnews.org/~takyon/
2. "Ketamine" - https://en.wikipedia.org/wiki/Ketamine
3. "Ketamine has 'fast-acting benefits' for depression" - http://www.bbc.com/news/health-43753073
4. "Medical Daily" - https://www.medicaldaily.com/ketamine-can-ease-depression-reduce-suicidal-thoughts-study-423582
5. "Efficacy and Safety of Intranasal Esketamine for the Rapid Reduction of Symptoms of Depression and Suicidality in Patients at Imminent Risk for Suicide: Results of a Double-Blind, Randomized, Placebo-Controlled Study" - https://ajp.psychiatryonline.org/doi/10.1176/appi.ajp.2018.17060720
6. "DX" - https://dx.doi.org/10.1176/appi.ajp.2018.17060720
7. "Can a Framework Be Established for the Safe Use of Ketamine?" - https://ajp.psychiatryonline.org/doi/10.1176/appi.ajp.2018.18030290
8. "DX" - https://dx.doi.org/10.1176/appi.ajp.2018.18030290
9. "FDA Designates MDMA as a "Breakthrough Therapy" for PTSD; Approves Phase 3 Trials" - https://soylentnews.org/article.pl?sid=17/08/30/0255213
10. "Study Suggests Psilocybin "Resets" the Brains of Depressed People" - https://soylentnews.org/article.pl?sid=17/10/14/1238206
11. "Ketamine Reduces Suicidal Thoughts in Depressed Patients" - https://soylentnews.org/article.pl?sid=17/12/16/1425213
12. "Studies Identify How Ketamine Can Reverse Symptoms of Depression" - https://soylentnews.org/article.pl?sid=18/02/18/0244214
13. "Over Years, Depression Changes the Brain, new Study Shows" - https://soylentnews.org/article.pl?sid=18/03/01/1856207
14. "Original Submission" - https://soylentnews.org/submit.pl?op=viewsub&subid=26023

printed from SoylentNews, Ketamine Shows Promise as a Fast-Acting Treatment for Depression on 2024-09-18 20:50:36