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Killing Superbugs With Star-shaped Polymers, Not Antibiotics

Accepted submission by Phoenix666 at 2016-09-13 14:23:24
Science

Tiny, star-shaped molecules are effective at killing bacteria [phys.org] that can no longer be killed by current antibiotics, new research shows.

The study, published today in Nature Microbiology, holds promise for a new treatment method against antibiotic-resistant bacteria (commonly known as superbugs).

The star-shaped structures, are short chains of proteins called 'peptide polymers', and were created by a team from the Melbourne School of Engineering.
...
tests undertaken on red blood cells showed that the star-shaped polymer dosage rate would need to be increased by a factor of greater than 100 to become toxic. The star-shaped peptide polymer is also effective in killing superbugs when tested in animal models.

Furthermore, superbugs showed no signs of resistance against these peptide polymers. The team discovered that their star-shaped peptide polymers can kill bacteria with multiple pathways, unlike most antibiotics which kill with a single pathway.

Let's hope any such molecules are thoroughly vetted with long-term studies before being introduced to medical therapies.


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