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Today’s Genital Warts Came from Trysts Between Neanderthals and Homo Sapiens

Accepted submission by Phoenix666 at 2016-10-19 13:19:00
Science

Genital warts, or human papillomavirus (HPV), isn't just a disease of the modern world and its newfangled sexual mores. In fact, various strains of HPV plagued our ancestors long before Homo sapiens evolved. A new study in Molecular Biology and Evolution [oxfordjournals.org] reveals that when the ancestors of Neanderthals and Denisovans left Africa over 500,000 years ago, they were already carrying a variant of HPV. The early humans who remained in Africa had their own variants of HPV, too. As the two populations evolved, their cancer-causing wart viruses evolved with them–until that fateful moment when Homo sapiens and Neanderthal came together, as it were [arstechnica.com].

A group of researchers in France and Spain used a common statistical modeling method to trace the evolutionary origins of today's HPV. By looking at mutated regions in the virus, which occur regularly over time, the researchers discerned that HPV's origins go back almost half a million years. The question was, how did various strains of HPV (including the extremely carcinogenic HPV16) make their way around the world? Currently, we see almost no HPV16 in Sub-Saharan Africa, while it's incredibly common elsewhere.

Our Cro-Magnon teenaged ancestors were not paying attention in Health class.


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