Gene discoveries give new hope to people who stutter:
There is no known cure, and existing treatments are often minimally effective. Yet for those with persistent, developmental stuttering, there is new hope, thanks to groundbreaking research led by scientists at Vanderbilt University Medical Center in Nashville, Tennessee, and Wayne State University in Detroit, Michigan.
In two papers published this week, Jennifer "Piper" Below, PhD, and Shelly Jo Kraft, PhD, describe a "genetic architecture" for developmental stuttering and report the discovery of new genetic variations associated with the condition.
The researchers said that these findings, which were published in The American Journal of Human Genetics and Human Genetics and Genomics Advances, and studies like them have the potential to identify therapeutic directions that could improve outcomes for people who stutter.
"It's clear that in populations, stuttering is polygenic, meaning that there are multiple different genetic factors contributing to and protecting people from risk," said Below, associate professor of Medicine at VUMC. "That was something that had not been clearly shown before these studies."
[...] "It's a piece of themselves that they can then understand," she said, "instead of living a lifetime of experiencing this difference in their speech and never knowing why."
Journal Reference:
Douglas M. Shaw, Hannah P. Polikowsky, Dillon G. Pruett, et al. Phenome risk classification enables phenotypic imputation and gene discovery in developmental stuttering. The American Journal of Human Genetics, 2021; 108 (12): 2271 DOI: 10.1016/j.ajhg.2021.11.004
(Score: 4, Interesting) by Common Joe on Tuesday December 07 2021, @08:00PM (1 child)
I wonder where I fit in. I don't stutter in my native language, but I stutter in my 2nd language.
(Score: 0) by Anonymous Coward on Tuesday December 07 2021, @10:50PM
Wh Wh Wh What is yo yo yo yo yo your 2ND la la language?
(Score: 1, Informative) by Anonymous Coward on Tuesday December 07 2021, @08:16PM (1 child)
cure your stutter yourself. no goofball geneticists necessary.
https://odysee.com/Fantastic-Fungi-(2019):c [odysee.com]
(Score: 0) by Anonymous Coward on Tuesday December 07 2021, @09:34PM
fungus amongous?
(Score: 3, Interesting) by Snotnose on Tuesday December 07 2021, @10:56PM (4 children)
About 15-20 years ago. He was one of the smartest guys I've ever known. One day I took a good look at the diploma he had framed on his office wall, it was his kindergarden diploma. I asked, he said "everyone has their college diploma, I wanted to be different".
My diploma has sat in a drawer somewhere (pretty sure I could find it if I had to) for 30+ years now, I never thought to hang it anywhere.
Dude is now Senior VP at some startup, I googled him for giggles several months ago.
It was really awkward to talk to him and wait patiently as he worked through his stutter to tell me how to solve my problem, or explain something to me. And I'm a good 30 years older than him. Not that age matters, I mention it because he was so young and I know his stutter held him back.
Of course I'm against DEI. Donald, Eric, and Ivanka.
(Score: 0) by Anonymous Coward on Wednesday December 08 2021, @06:08AM (1 child)
Why can't all stutterers be like that. I'm sick of them living off welfare, ducking and jiving, stealing watermelons etc.
(Score: 1, Touché) by Anonymous Coward on Wednesday December 08 2021, @04:19PM
Defeating Trump.
(Score: 0) by Anonymous Coward on Wednesday December 08 2021, @04:56PM
> he said "e-e-e-e-everyone h-h-h-has their c-c-c-c-college diploma, I w-w-w-w-w-wanted to be d-d-d-d-d-d-d-d-d-d-d-d-d-d-d-d-d-d-d-d-d-d-d-different".
FTFY
(Score: 0) by Anonymous Coward on Thursday December 09 2021, @01:54PM