The Coalition for Epidemic Preparedness Innovations (CEPI) will attempt to develop vaccines for Middle East respiratory syndrome (MERS), Lassa fever, and Nipah virus within the next five years. CEPI is seeking another half billion dollars of funding at the World Economic Forum:
Scientists have named three relatively little-known diseases they think could cause the next global health emergency. A coalition of governments and charities has committed $460m to speed up vaccine development for Mers, Lassa fever and Nipah virus. They are asking funders at the World Economic Forum Davos for another $500m. The Coalition for Epidemic Preparedness Innovations aims to have two new experimental vaccines ready for each disease within five years.
CEPI was formed in the wake of the Ebola crisis to speed up vaccine development:
The devastating Ebola epidemic that erupted in West Africa in 2014 sparked the formation of CEPI. Experimental Ebola vaccines, which have no commercial market, were sitting in laboratory freezers when the epidemic broke out, but they had never been tested in humans. Clinical trials began in haste in September 2014, but vaccine development is a multiphase process that requires first conducting small-scale studies for safety and immune responses in hundreds of people who are not at risk for the disease. Vaccines that pass those tests move on to real-world efficacy trials in thousands of volunteers. By the time an Ebola vaccine proved its worth in July 2015, standard containment efforts had already nearly brought the epidemic to a standstill.
Jeremy Farrar, head of the Wellcome Trust in London, co-authored an influential perspective in the 23 July 2015 issue of The New England Journal of Medicine that spelled out the need for a coordinated global effort to help advance vaccines against menacing infectious diseases that industry ignored because of dodgy markets. The article proposed taking novel vaccines through preliminary human testing before the inevitable outbreaks—an idea that has now evolved into CEPI. "We now have enough money to show the world that this can deliver," says Farrar, who is on the interim CEPI board. CEPI will now solicit proposals from academic researchers and industry to develop candidate vaccines for its three target viruses.
NASA wants to uncover the mystery behind the asteroid “16 Psyche.” that may contain a priceless treasure trove of minerals. “We’ve been to all the different planets, we’ve been to other asteroids. But we’ve never visited a body that has been made of entirely metal,” said Carol Polanskey, project scientist for the Psyche mission. Now NASA, led by researchers at Arizona State University, plans to send an unmanned spacecraft to orbit 16 Psyche – an asteroid roughly the size of Massachusetts, made of iron and other precious metals. The mission’s leader estimates that the iron alone on today’s market would be worth $10,000 quadrillion.
Previously: NASA Selects Two Missions to Visit Asteroids
Alexey Yablokov and Chris Busby are biologists whose efforts have been to make people aware of the negative health effects of very low-dose ionizing radiation.
Chris Busby reports via CounterPunch
There will be many obituaries published about Alexey V. Yablokov, the extraordinary Russian scientist, activist, and human being, but I would like to briefly record a few words about the man I knew. And to weep a few tears.
He was a strong [...] friend and fellow fighter for truth, and his recent death on the evening of January 10th means a lot for me--and (though we may [not] know it) for us all on this increasingly contaminated planet.
[...] He, like me, saw the issue of radiation and health as one which was fundamentally a political one, and only secondarily as scientific.
[...] In 1998, [...] Alexey and I [...] with Inge Schmitz-Feuerhake, Alice Stewart, and (later) Molly Scott Cato [...] decided to form an alternative [to ICRP, the International Commission on Radiological Protection]: the European Committee on Radiation Risk (ECRR).
This needed an alternative radiation risk model, and we worked on this over the next five years to create the first ECRR report which was published in 2003 and rose upon the nuclear industry horizon with the brightness of a thousand suns.
For years now, AGDQ [Awesome Games Done Quick] has featured a block where TASBot (the Tool-Assisted Speedrun Robot) performs literally superhuman feats on classic consoles simply by sending data through the controller ports thousands of times per second. This year's block (viewable above) started off simply enough, with some show-offy perfect play of Galaga and Gradius on the new NES Classic hardware using a device made by TASBot team member Peter Greenwood (who goes by the name micro500). TASBot organizer dwangoAC Allan Cecil (dwangoAC) described the NES Classic as "absolutely horrible" when it comes to automation.
After that, TASBot moved on to a few "total control runs," exploiting known glitches in Super Mario Bros. 3 and Mega Man to insert arbitrary code on the NES. This is nothing new for the computer-driven TASBot—the basics of the tricks vary by game, but they generally involve using buffer overflows to get into memory, then bootstrapping a loader that starts reading and executing a stream of controller inputs as raw assembly level opcodes. The method was taken to ridiculous extremes last year, when TASbot managed to "beat" Super Mario Bros. 3 in less than a second with a very specific total control glitch.
With those out of the way, TASBot moved on to a similar total control run of The Legend of Zelda: A Link to the Past. After a few minutes of setup, the Zelda screen faded out, then faded back in on a bordered window with an ersatz logo for the "Super N64." Without any forthcoming explanation from the runners on stage, TASBot started apparently playing through a glitch-filled speedrun of Super Mario 64 on the Super NES, following it up with a similar glitch-filled speedrun through Valve's PC classic Portal. After that, the scene somehow transitioned to a Skype video call with a number of speedrunners speaking live from the AGDQ event through the SNES.
No one on the AGDQ stage acknowledged how weird this all was, leaving hundreds in the Herndon, VA ballroom and nearly 200,000 people watching live on Twitch temporarily guessing at what, exactly, was going on.
Very geeky but very cool. And totally impractical.
Netflix's foray into original content is paying off:
[Rather] than pay money out to studios for the right to show existing content, it instead ploughed its cash into shows such as Stranger Things, The Crown, Luke Cage and the remake of Gilmore Girls. In 2016, those "Netflix Originals" - already a term you could argue has become synonymous with quality - came thick and fast. The firm said it produced 600 hours of original programming last year - and intends to raise that to about 1,000 hours in 2017. Its budget to achieve that is $6bn - a billion more than last year.
On Wednesday we learned the company has been rewarded handsomely for putting its eggs in the original content basket. After hours trading on Wednesday saw the company's stock rise by as much as 9% on the news it had added 7.05 million new subscribers in the last three months of 2016. That's far greater than the 5.2 million they had anticipated, and left them ending the year with 93.8 million subscribers in total - and an expectation of breaking the symbolic 100 million mark by the end of March. In all, 2016 saw Netflix take in $8.83bn in revenue - with a profit of $186.7m.
With unlimited data plans becoming increasingly expensive, or subscribers being forced to ditch their unlimited data due to overuse, anything that can reduce the amount of data we download is welcome. This is especially true for media including images or video, and Google just delivered a major gain when it comes to viewing images online.
The clever scientists at Google Research have come up with a new technique for keeping image size to an absolute minimum without sacrificing quality. So good is this new technique that it promises to reduce the size of an image on disk by as much as 75 percent.
The new technique is called RAISR, which stands for "Rapid and Accurate Image Super-Resolution." Typically, reducing the size of an image means lowering its quality or resolution. RAISR works by taking a low-resolution image and upsampling it, which basically means enhancing the detail using filtering. Anyone who's ever tried to do this manually knows that the end result looks a little blurred. RAISR avoids that thanks to machine learning.
[...] RAISR has been trained using low and high quality versions of images. Machine learning allows the system to figure out the best filters to recreate the high quality image using only the low quality version. What you end up with after lots of training is a system that can do the same high quality upsampling on most images without needing the high quality version for reference.
-- submitted from IRC
Submitted via IRC for TheMightyBuzzard
Besides the fact that antiX 16.1 comes with all 173 bug fixes and security patches implemented by the Debian Project in the new Debian GNU/Linux 8.7 "Jessie" release, but without the systemd init system, the distribution is using the long-term supported Linux 4.4.10 kernel customized with a fbcondecor splash.
Additionally, the new antiX version includes two applications, namely live-usb-maker and live-kernel-updater, which allow users to create a Live USB disk of antiX that you can use to run the operating system without having to install it on your personal computer, and update the kernel without the need to reboot the PC.
Meh, I'll stick with Calculate Linux for now.
Turkey's ruling party is passing constitutional reforms to consolidate power:
Turkey's parliament approved the first seven articles in a second round of voting overnight on a constitutional bill that will extend President Tayyip Erdogan's powers, keeping the reform on course for a spring referendum.
The two largest opposition parties in parliament say the 18-article bill, which could enable Erdogan to rule until 2029, will fuel authoritarianism in the NATO member and European Union candidate country. The ruling AK Party, backed by the nationalist MHP, says it will bring the strong executive leadership needed to prevent a return to the fragile coalition governments of the past.
The seven articles approved overnight include increasing the number of MPs to 600 from 550, lowering the minimum age to be a lawmaker to 18 from 25, and holding parliamentary and presidential elections together every five years.
Amazon is preparing to test experimental wireless communications technology, including mobile devices and fixed-base stations, in rural Washington and Seattle, the company disclosed in government filings this week.
The filings do not specify what the tests would be for, but they hint at a new type of technology or wireless service, noting that the project would involve prototypes designed to support "innovative communications capabilities and functionalities."
Even more intriguing is that Amazon listed Neil Woodward as the main contact on the filings. Woodward, a retired NASA astronaut who joined Amazon in 2008, is now a senior manager for Prime Air, the team in charge of Amazon's drone-delivery effort, according to his LinkedIn page.
That suggests the tests could involve some kind of communications system to control Amazon's delivery drones. But the details in the filings could also point to a wireless service designed to work with mobile handsets, such as Amazon's Kindle tablets, or perhaps the Echo home speakers that Amazon sells.
-- submitted from IRC
Arthur T Knackerbracket has found the following story:
When Nvidia popped the bonnet on its Co-Pilot "backseat driver" AI at this year's Consumer Electronics Show, most onlookers were struck by its ability to lip-read while tracking CES-going "motorists'" actions within the "car".
[...] An Nvidia spokesperson has since confirmed in an email to The Register that the lip-reading component was based on research paper [PDF] written by academics from the University of Oxford, Google DeepMind and the Canadian Institute for Advanced Research.
"We are really happy to see LipNet in such an application and [it] is the proof that our novel architecture is scalable to real-world problems," the research team added in an email to El Reg.
[...] The paper was initially criticised. Although the neural network, LipNet, had an impressive accuracy rate of 93.4 per cent, it was only tested on a limited dataset of words and not coherent sentences.
A second paper, unofficially published on arXiv, showed LipNet's capabilities had improved. It could now decipher complete sentences after it had been trained to watch the speech movements of BBC News presenters for several hours.
-- submitted from IRC
In a December 12 exposé occupying two full spreads in Guangzhou's Southern Metropolis Daily, reporters Rao Lidong (饶丽冬) and Li Ling (李玲) carefully documented their successful attempts to obtain personal information about consenting colleagues through "tracking" services advertised online.
For a modest fee of 700 yuan, or about 100 dollars, the reporters were able to obtain an astonishing array of information based on one colleague's personal ID number, including a full history of hotel rooms checked into, airline flights taken, internet cafes visited, border entries and exits, apartment rentals, real estate holdings — even deposit records from the country's four major banks.
But that wasn't all. The reporters were also able to purchase live location data on another colleague's mobile phone, pinpointing their position with disturbing accuracy.
Hundreds of tracking services are advertised on internet-based platforms in China, offering clients the power to unlock, with as little as a phone number or ID, the personal data of just about any Chinese citizen. You can find them on Tencent's WeChat and QQ services, on the Taobao online marketplace and on Weibo. And while some of these services are unreliable or outright fraudulent, others are able to deliver accurate information from what must be national police and government databases, as well as from banks and mobile carriers.
In other words, through a simple mobile transaction, you, too, can be Big Brother.
In Hallstatt, Austria, a picturesque village nestled into a lake-peppered region called Salzkammergut, Kunze has spent the past four years engraving images and text onto hand-sized clay squares. A ceramicist by trade, he believes the durability of the materials he plies gives them an as-yet unmatched ability to store information. Ceramic is impervious to water, chemicals, and radiation; it's emboldened by fire. Tablets of Sumerian cuneiform are still around today that date from earlier than 3000 B.C.E.
"The only thing that can threaten this kind of data carrier is a hammer," Kunze says.
[...] The goal of the project, which he calls the Memory of Mankind, is to build up a complete, unbiased picture of modern societies. The sheets will be stored along with the larger tablets in a vault 2 km inside Hallstatt's still-active salt mine. If all goes according to plan, the vault will naturally seal over the next few decades, ready for a curious future generation to open whenever it's deemed necessary.
To Kunze, this peculiar ambition is more than a courtesy to future generations. He believes the age of digital information has lulled people into a false sense that memories are forever preserved. If today's digital archives disappear—or, in Kunze's view, when they do—he wants to make sure there's a real, physical record to mark our era's place in history.
Arthur T Knackerbracket has found the following story:
The popular Samsung SmartCam security cameras contain a critical remote code execution vulnerability that could allow hackers to gain root access and take full control of them.
The vulnerability was discovered by researchers from the hacking collective the Exploiteers (formerly GTVHacker), who have found vulnerabilities in the Samsung SmartCam devices in the past.
The flaw allows for command injection through a web script, even though the vendor has disabled the local web-based management interface in these devices.
The Samsung SmartCam is a series of cloud-enabled network security cameras that were originally developed by Samsung Techwin. Samsung sold this division to South Korean business conglomerate Hanwha Group in 2015 and the company was renamed Hanwha Techwin.
In response to vulnerabilities reported in the web-based management interface of various SmartCam models over the past few years, Hanwha Techwin decided to completely disable the local administration panel and allow users to access the cameras only through the accompanying smartphone app and its My SmartCam cloud service.
[...] While the flaw was found in the SNH-1011 model, the researchers believe that it affects the entire Samsung SmartCam series.
Ironically, the vulnerability can be exploited to turn on the disabled web-management interface, whose removal was criticized by some users. The Exploiteers published a proof-of-concept exploit that does just that. They also provided instructions on how to manually patch the flaw.
Re-enabling the web interface will allow users to monitor the camera feed via the local network again without having to use the My SmartCam service. But there's a catch: It also reactivates some of the old vulnerabilities that the vendor mitigated by simply disabling the interface in the first place.
Also covered at Ars Technica .
-- submitted from IRC
Arthur T Knackerbracket has found the following story:
For the past couple of years, browser makers have raced to migrate from SHA-1 to SHA-2 as researchers have intensified warnings about collision attacks moving from theoretical to practical. In just weeks, a transition deadline set by Google, Mozilla and Microsoft for the deprecation of SHA-1 is up.
Starting on Jan. 24, Mozilla's Firefox browser will be the first major browser to display a warning to its users who run into a site that doesn't support TLS certificates signed by the SHA-2 hashing algorithm. The move protects users from collision attacks, where two or more inputs generate the same hash value.
In 2012, Bruce Schneier projected a collision attack SHA-1 would cost $700,000 to perform by 2015 and $143,000 by 2018. In 2015, researchers said tweaks to existing attacks and new understanding of the algorithm could accelerate attacks and make a full-on collision attack feasible for somewhere between $75,000 to $125,000.
Experts warn the move [to] SHA-2 comes with a wide range of side effects; from unsupported applications, new hardware headaches tied to misconfigured equipment and cases of crippled credit card processing gear unable to communicate with backend servers. They say the entire process has been confusing and unwieldy to businesses dependent on a growing number of digital certificates used for not only their websites, but data centers, cloud services, and mobile apps.
In a new study, researchers at the University of California San Diego investigate why hair is incredibly strong and resistant to breaking. The findings could lead to the development of new materials for body armor and help cosmetic manufacturers create better hair care products.
Hair has a strength to weight ratio comparable to steel. It can be stretched up to one and a half times its original length before breaking.
[...] The faster hair is stretched, the stronger it is. "Think of a highly viscous substance like honey," Meyers explained. "If you deform it fast it becomes stiff, but if you deform it slowly it readily pours."
Hair consists of two main parts -- the cortex, which is made up of parallel fibrils, and the matrix, which has an amorphous (random) structure. The matrix is sensitive to the speed at which hair is deformed, while the cortex is not. The combination of these two components, Yu explained, is what gives hair the ability to withstand high stress and strain.
And as hair is stretched, its structure changes in a particular way. At the nanoscale, the cortex fibrils in hair are each made up of thousands of coiled spiral-shaped chains of molecules called alpha helix chains. As hair is deformed, the alpha helix chains uncoil and become pleated sheet structures known as beta sheets. This structural change allows hair to handle up a large amount deformation without breaking.
An abstract is available but the full article is paywalled.