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Scientists Freeze Brains, Then Thaw Them – and They're in Perfect Order

Accepted submission by Phoenix666 at 2016-02-12 12:30:32
Science

Scientists have preserved and recovered cryogenically-frozen brains in near-perfect condition [theregister.co.uk].

Robert McIntyre and Gregory Fahy from 21st Century medicine [21cm.com] were able to prevent neuron shrinkage that follows dehydration.

The pair used ultrafast chemical fixation and a new cryogenic storage technique called aldehyde-stabilised cryopreservation (ASC) to preserve and thaw rabbit and pig brains.

The Brain Preservation Foundation announced [brainpreservation.org] the team had won the Small Mammal Brain Preservation Prize for the work first published last August in the paper Aldehyde-stabilized cryopreservation [PDF [sciencedirect.com]].

"To demonstrate the feasibility of ASC, we perfuse-fixed rabbit and pig brains with a glutaraldehyde-based fixative, then slowly perfused increasing concentrations of ethylene glycol over several hours in a manner similar to techniques used for whole organ cryopreservation," the pair say in the paper.


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