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Humanoid Robots Could "Wear" Tissue Grafts Before Transplantation

Accepted submission by takyon at 2017-03-02 02:31:34
Science

Humanoid robots could be used to stretch and strain bioengineered tissues [arstechnica.com], providing them a suitable environment for growth:

Right now, tissue engineering relies on bioreactors to grow sheets of cells. These machines often look like large fish tanks, filled with a rich soup of nutrients and chemicals that cells need to grow on a specialized trellis. The problem, explain Mouthuy and Carr, is that bioreactors currently "fail to mimic the real mechanical environment for cells." In other words, human cells in muscles and tendons grow while being stretched and moved around on our skeletons. Without experiencing these natural stresses, the tissue grafts produced by researchers often have a broad range of structural problems and low cell counts.

That's where robots come in. The researchers propose a "humanoid-bioreactor system" with "structures, dimensions, and mechanics similar to those of the human body." As the robot interacted with its environment, tissues growing on its body would receive the typical strains and twists that they would if they grew on an actual human. The result would be healthy tissue, grown for the exact area on the body it was destined to replace. Mouthuy and Carr note that this would be especially helpful for "bone-tendon-muscle grafts... because failure during healing often occurs at the interface between tissues."

What would this humanoid-bioreactor system look like? It could possibly be built on top of a humanoid robot with "soft robotics" muscles made from electroactive polymers, and the growing muscles could piggyback on those to get their exercise. It would also need to be covered in soft, stretchable sensors to monitor the health of the growing tissues.

Growing tissue grafts on humanoid robots: A future strategy in regenerative medicine? [sciencemag.org] (open, DOI: 10.1126/scirobotics.aam5666) (DX [doi.org])


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