Various news outlets are reporting on an announcement by the Venezuelan government that it will leave the Organization of American States [wikipedia.org] (OAS), a process that takes two years. The country will stop participating in OAS meetings immediately. No country has left the OAS since its founding in 1948.
According to Venezuela-based teleSUR [telesurtv.net], the move comes in response
[...] to a meeting of the Permanent Council of the Organization of American States to discuss Venezuela scheduled for Wednesday, which violates the rules of the organization because it does not have the consent of the affected country.
[The foreign minister] indicated that there is also a group of countries with right-wing governments working under U.S. imperialist orders against Venezuela.
According to ABC News, [go.com]
Hundreds of thousands have taken to the streets demanding [President Nicolás] Maduro hold elections and denouncing his government as being responsible for triple-digit inflation, food shortages and a rise [in] crime.
It also says that 29 people have been killed in connection with the protests.