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NIH Contributed to the Research Behind Every One of 210 Newly Approved Drugs

Accepted submission by takyon at 2018-02-13 18:27:23
Science

An analysis of research papers has found that the National Institutes of Health (NIH) provided funding to the research [statnews.com] of 210 new drugs that were approved from 2010 and 2016:

A new study makes a strong case for the importance of government support for basic research: Federally funded studies contributed to the science that underlies every one of the 210 new drugs approved between 2010 and 2016.

Researchers at Bentley University scoured millions of research papers for mentions of those 210 new molecular entities, or NMEs, as well as studies on their molecular targets. Then, they looked to see which of those studies had received any funding from the National Institutes of Health.

The authors say the study, published Monday in Proceedings of the National Academy of Sciences, is the first to capture the full scope of public funding behind FDA-approved drugs, both directly and indirectly. They also say it points to the need for continued federal funding for basic science — which the Trump administration has previously suggested slashing.

"Knowing the scale of the investment in the basic science leading to new medicines is critical to ensuring that there is adequate funding for a robust pipeline of new cures in the future," said Dr. Fred Ledley, one of the study's authors and a Bentley University researcher who studies the intersection of science and industry.

Contribution of NIH funding to new drug approvals 2010–2016 [pnas.org] (open, DOI: 10.1073/pnas.1715368115) (DX [doi.org])


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