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https://gizmodo.com/a-once-a-day-male-birth-control-pill-shows-promise-in-h-1823890390 [gizmodo.com]

One of the latest experimental candidates for a male birth control drug is a compound that would be taken much like the daily birth control pill available for women. A pilot study presented Sunday at the Endocrine Society’s annual meeting suggests that the compound—called dimethandrolone undecanoate (DMAU)—can be safe and effective in human test subjects.

[...] DMAU is meant to act on the same receptors as testosterone and progestin. But it seems to be more easily absorbed by the body and longer-lasting. That theoretically means a single dose a day (when taken with food) should cause sterility without leading to other serious consequences, the authors say.

[...] The few side effects Page’s team observed were weight gain and lowered levels of HDL cholesterol (the “good” kind). But they feel a tweaked dose could alleviate these symptoms. Importantly, the pill didn’t seem to cause any other lasting symptoms of low testosterone. Eight men in the treatment group did report lower libido, but the effect faded away after treatment had ended.

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