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Secrets of Mighty Cancer Killing Virus Unlocked

Accepted submission by Phoenix666 at 2018-10-31 14:42:01
Science

Science Daily [sciencedaily.com]:

University of Otago researchers have used high-resolution electron microscopy images to reveal how an anti-cancer virus interacts with tumor cells, increasing its potential to save lives.

Seneca Valley Virus (SVV), a newly discovered virus which infects cancer cells but not normal tissue, has become a main research project in the New Zealand laboratory of Dr Mihnea Bostina, Academic Director of Otago's OMNI Electron Microscopy unit and senior lecturer in the Department of Microbiology and Immunology.
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The virus is a strong contender for effective virotherapy because it selectively targets a receptor found only in tumor cells in more than 60 per cent of human cancers.

The receptor, a protein called ANTXR1, is expressed on tumors, but it has a cousin, ANTXR2, that only appears on healthy tissues. SVV doesn't bind with the similar receptor on healthy cells -- it only shows strong affinity for ANTXR1.

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