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doi-10.7326/M21-0878

Nearly 40% have Long Covid after 7 months, finds Swiss study [lenews.ch]:

The longer term effects of Covid-19 can take many forms and there are numerous definitions of the disease. A study undertaken by HUG and UNIGE in Geneva, published on 6 July 2021, found that 39% of a group of Covid-19 patients still had symptoms after 7 months.

Of the 629 participants in the study who completed the interviews, 410 completed the follow-up at 7 to 9 months after a COVID-19 diagnosis in early 2020. Of this group, 39.0% reported residual symptoms at 7 to 9 months. Fatigue (20.7%) was the most common symptom, followed by loss of taste or smell (16.8%), shortness of breath (11.7%), and headache (10.0%).

Some had symptoms that persisted, some had symptoms that arrived after a delay, while others had symptoms that came, went, and returned later.

Of the 311 participants that responded at all 3 follow-up time points, 37% reported symptom resolution by 30 to 45 days and 19% by 7 to 9 months. 27% reported symptoms at all 3 time points and 10% reported symptoms at the start and at 7 to 9 months but not at 30 to 45 days. Finally, 4% of participants reported no symptoms at all 3 time points, 2% had no symptoms at baseline but had symptoms at 30 to 45 days and 7 to 9 months, and 1 person had no symptoms at the start and 30 to 45 days but had symptoms at 7 to 9 months.

The study authors concluded that residual symptoms following SARS-CoV-2 infection are common among otherwise young and healthy persons and recommend long-term monitoring.

The mean age of those studied was 42.1 years, 60.9% were women, 25.3% were health care workers, and 70.7% had no underlying risk factors.

More on this:
Research report [acpjournals.org] (in English)

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Journal Reference:
Mayssam  Nehme , Olivia  Braillard , François  Chappuis , et al. Prevalence of Symptoms More Than Seven Months After Diagnosis of Symptomatic COVID-19 in an Outpatient Setting [open], Annals of Internal Medicine (DOI: 10.7326/M21-0878 [doi.org])

Original Submission