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'Super melanin' heals skin injuries from sunburn, chemical burns

Accepted submission by taylorvich at 2023-11-02 16:13:40 from the Medicine dept.
Science

https://medicalxpress.com/news/2023-11-super-melanin-skin-injuries-sunburn.html [medicalxpress.com]

Imagine a skin cream that heals damage occurring throughout the day when your skin is exposed to sunlight or environmental toxins. That's the potential of a synthetic, biomimetic melanin developed by scientists at Northwestern University.

In a new study, the scientists show that their synthetic melanin, mimicking the natural melanin in human skin, can be applied topically to injured skin, where it accelerates wound healing. These effects occur both in the skin itself and systemically in the body.

When applied in a cream, the synthetic melanin can protect skin from sun exposure and heals skin injured by sun damage or chemical burns, the scientists said. The technology works by scavenging free radicals, which are produced by injured skin such as a sunburn. Left unchecked, free radical activity damages cells and ultimately may result in skin aging and skin cancer.

The study, titled "Topical Application of Synthetic Melanin Promotes Tissue Repair," is published Nov. 2 in npj Regenerative Medicine.

Melanin in humans and animals provides pigmentation to the skin, eyes and hair. The substance protects your cells from sun damage with increased pigmentation in response to sunlight—a process commonly referred to as tanning. That same pigment in your skin also naturally scavenges free radicals in response to damaging environmental pollution from industrial sources and automobile exhaust fumes.


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