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https://phys.org/news/2026-03-graphene-oxide-bacteria-human-cells.html [phys.org]
Hygiene in everyday items that touch the body—such as clothing, masks, and toothbrushes—is critically important. The underlying principle of how graphene selectively eliminates only bacteria has now been revealed. In Advanced Functional Materials, [wiley.com] a KAIST research team presents the potential for a next-generation antibacterial material that is safe for the human body and capable of replacing antibiotics.
A joint research team led by Professor Sang Ouk Kim from the Department of Materials Science and Engineering and Professor Hyun Jung Chung from the Department of Biological Sciences has identified the mechanism by which graphene oxide (GO) exhibits powerful antibacterial effects against bacteria while remaining harmless to human cells.
Graphene oxide is a nanomaterial consisting of an atomic level carbon layer (graphene) with oxygen attached; it is characterized by its ability to mix well with water and implement various functions.
This study is highly significant as it provides molecular-level proof [phys.org] of graphene's antibacterial action, which had not been clearly understood until now.
The research team confirmed that graphene oxide performs "selective antibacterial action" by attaching to and destroying only the membranes of bacteria, much like a magnet attaches only to specific metals, while leaving human cells untouched. This occurs because the oxygen functional groups on the surface of graphene oxide selectively bind with a specific component (POPG) found only in bacterial cell membranes.
Simply put, it recognizes a "target" present only in bacterial membranes to attach and destroy the structure. In this context, phospholipids [phys.org] are fatty components that make up the membrane surrounding a cell, and POPG is a component primarily present in bacteria.
Furthermore, fibers using this material [phys.org] maintained their antibacterial functions even after multiple washes, showing potential for use in various industrial fields such as apparel and medical textiles.
This technology is already being applied to consumer products. The graphene antibacterial toothbrush, released through the original patents of the faculty-led startup "Materials Creation Co., Ltd.," has sold over 10 million units, proving its commercial viability.
Additionally, GrapheneTex—textile material incorporating this technology—was used in the uniforms of the Taekwondo demonstration team at the 2024 Paris Olympics and is expected to play an active role in functional sportswear at upcoming international sporting events like the 2026 Asian Games.
Professor Sang Ouk Kim explained, "This study is an example of scientifically uncovering why graphene can selectively kill bacteria while remaining safe for the human body." He emphasized, "By utilizing this principle, we can expand beyond safe clothing without harsh chemicals to an infinite range of applications, including wearable devices and medical textile systems."
Sujin Cha et al, Biocompatible but Antibacterial Mechanism of Graphene Oxide for Sustainable Antibiotics, Advanced Functional Materials (2026). DOI: 10.1002/adfm.74695 [doi.org]
Journal information: Advanced Functional Materials [phys.org] [wiley.com]
Provided by The Korea Advanced Institute of Science and Technology (KAIST) [phys.org] [kaist.edu]
Graphene oxide kills bacteria by selectively binding to POPG phospholipids unique to bacterial membranes via its oxygen functional groups, disrupting bacterial cells while sparing human cells. This mechanism enables durable antibacterial effects in textiles and consumer products without harming human tissue, supporting its use as a safe alternative to conventional antibiotics.
This summary was automatically generated using LLM. Full disclaimer [sciencex.com]