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posted by chromas on Tuesday April 17 2018, @05:12AM   Printer-friendly
from the ask-your-doctor-about-it-now dept.

Ketamine could become an approved treatment for depression in the UK soon:

Ketamine has 'fast-acting benefits' for depression

Ketamine has "shown promise" in the rapid treatment of major depression and suicidal thoughts, a US study says. Ketamine has a reputation as a party drug but is licensed as an anaesthetic. The study found use of the drug via a nasal spray led to "significant" improvements in depressive symptoms in the first 24 hours. The Royal College of Psychiatrists said it was a "significant" study that brought the drug "a step closer to being prescribed on the NHS".

The report by researchers from Janssen Research and Development, a Johnson and Johnson company, and Yale School of Medicine, is the first study into ketamine as a treatment for depression that has been done by a drug company.

[...] The study found those using esketamine had a much greater improvement in depression symptoms at all points over the first four weeks of treatment. However, at 25 days the effects had levelled out. The study's authors suggest it could offer an effective rapid treatment for people severely depressed and at imminent risk of suicide and could help in the initial stages of treatment, as most anti-depressants take four to six weeks to become fully effective.

Also at Medical Daily.

Efficacy and Safety of Intranasal Esketamine for the Rapid Reduction of Symptoms of Depression and Suicidality in Patients at Imminent Risk for Suicide: Results of a Double-Blind, Randomized, Placebo-Controlled Study (DOI: 10.1176/appi.ajp.2018.17060720) (DX)

Can a Framework Be Established for the Safe Use of Ketamine? (DOI: 10.1176/appi.ajp.2018.18030290) (DX)

Related: FDA Designates MDMA as a "Breakthrough Therapy" for PTSD; Approves Phase 3 Trials
Study Suggests Psilocybin "Resets" the Brains of Depressed People
Ketamine Reduces Suicidal Thoughts in Depressed Patients
Studies Identify How Ketamine Can Reverse Symptoms of Depression
Over Years, Depression Changes the Brain, new Study Shows


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  • (Score: 0) by Anonymous Coward on Tuesday April 17 2018, @05:30AM (2 children)

    by Anonymous Coward on Tuesday April 17 2018, @05:30AM (#667956)

    This needs to be adapted into a long term solution so no one will be sad, ever again. Do you have anything against making everyone being happy and content?
    :)

    • (Score: 2) by DannyB on Tuesday April 17 2018, @02:15PM

      by DannyB (5839) Subscriber Badge on Tuesday April 17 2018, @02:15PM (#668083) Journal

      As long as they are also being productively and not are too much sedated or thinking not clearly.

      --
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    • (Score: 1, Insightful) by Anonymous Coward on Tuesday April 17 2018, @04:14PM

      by Anonymous Coward on Tuesday April 17 2018, @04:14PM (#668158)

      I know you are being slightly sarcastic with your post. That said, I want to ensure the real benefit of treating highly depressed people is highlighted. Bringing a highly depressed person back from the edge is a huge win; they don't have to get to "pure happy time", just enough so they can get some help and work on the overall depression they have. Discoveries like this will help many, many people and their families in the future.

  • (Score: 2) by ilPapa on Tuesday April 17 2018, @06:41AM

    by ilPapa (2366) on Tuesday April 17 2018, @06:41AM (#667960) Journal

    Hook me up.

    https://youtu.be/Kt0Xuw02TMQ [youtu.be]

    --
    You are still welcome on my lawn.
  • (Score: -1, Offtopic) by Anonymous Coward on Tuesday April 17 2018, @08:41AM (8 children)

    by Anonymous Coward on Tuesday April 17 2018, @08:41AM (#667967)

    cos im evil

    • (Score: 2) by acid andy on Tuesday April 17 2018, @02:56PM (7 children)

      by acid andy (1683) on Tuesday April 17 2018, @02:56PM (#668114) Homepage Journal

      That's a sin, for which your hide should be tanned. Just a sec, sin, cos, tan?

      --
      If a cat has kittens, does a rat have rittens, a bat bittens and a mat mittens?
      • (Score: 0) by Anonymous Coward on Tuesday April 17 2018, @06:58PM (6 children)

        by Anonymous Coward on Tuesday April 17 2018, @06:58PM (#668246)

        Did I trigger you :P Seemed I got tanned and downvoted as off-topic :D

        wikipedia...
        In veterinary anesthesia, ketamine is often used for its anesthetic and analgesic effects on cats,[216] dogs,[217] rabbits, rats, and other small animals.[218][219] It is highly used in induction and anesthetic maintenance in horses. It is an important part of the "rodent cocktail", a mixture of drugs used for anesthetizing rodents.[220] Veterinarians often use ketamine with sedative drugs to produce balanced anesthesia and analgesia, and as a constant-rate infusion to help prevent pain wind-up. Ketamine is used to manage pain among large animals, though it has less effect on bovines and off-topic downvoters.

        • (Score: 2) by acid andy on Tuesday April 17 2018, @08:32PM (5 children)

          by acid andy (1683) on Tuesday April 17 2018, @08:32PM (#668289) Homepage Journal

          Nah it was just a severely nerdy joke about trigonometry (sine, cosine, tangent, secant) but if I have to explain it I guess it's too obscure for anyone.

          --
          If a cat has kittens, does a rat have rittens, a bat bittens and a mat mittens?
          • (Score: 0) by Anonymous Coward on Tuesday April 17 2018, @09:15PM (4 children)

            by Anonymous Coward on Tuesday April 17 2018, @09:15PM (#668295)

            it was a pun you know

            • (Score: 3, Informative) by takyon on Tuesday April 17 2018, @11:49PM (3 children)

              by takyon (881) <takyonNO@SPAMsoylentnews.org> on Tuesday April 17 2018, @11:49PM (#668342) Journal

              Thread is a fail, time to hit the dank ketamine.

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              [SIG] 10/28/2017: Soylent Upgrade v14 [soylentnews.org]
              • (Score: 0) by Anonymous Coward on Wednesday April 18 2018, @12:42AM (2 children)

                by Anonymous Coward on Wednesday April 18 2018, @12:42AM (#668359)

                where to get ketamine

                • (Score: 0) by Anonymous Coward on Wednesday April 18 2018, @05:19AM (1 child)

                  by Anonymous Coward on Wednesday April 18 2018, @05:19AM (#668438)

                  dream market

                  • (Score: 0) by Anonymous Coward on Wednesday April 18 2018, @05:29AM

                    by Anonymous Coward on Wednesday April 18 2018, @05:29AM (#668440)

                    Soylentdeepdarkmarket is better as they provide drugs and all relevent research papers.

  • (Score: 2) by Pav on Wednesday April 18 2018, @01:38PM

    by Pav (114) on Wednesday April 18 2018, @01:38PM (#668558)

    ...and for some reason they put me on ketamine. I have no idea why anyone would do that shit recreationally. I was in screaming agony and the ketamine did noting for that, but I just didn't give a crap - the ketamine saw to it that I had no emotional response to the pain, or to anything really. The head nurse said "we should take him off the ketamine" - I realised I was in screaming agony, so that when I was pulled off the ketamine I WOULD care. The thing is I just didn't care about ANYTHING, including telling her this... well... up until the ketamine wore off anyway. :)

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