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Now, in research published in Science, an Université de Montréal biologist has figured out why, and his findings could have implications for, of all things, the future of space travel . By studying a variety called the 13-lined ground squirrel that is common in North America, Matthew Regan has confirmed a theory known as "urea nitrogen salvage" dating back to the 1980s.
The theory posits that hibernators harness a metabolic trick of their gut microbes to recycle the nitrogen present in urea, a waste compound that is usually excreted as urine, and use it to build new tissue proteins.
How could this discovery be of use in space? Theoretically, Regan posits, by helping astronauts minimize their own muscle-loss problems caused by microgravity-induced suppression of protein synthesis and which they now try to reduce by intensively exercising.
If a way could be found to augment the astronauts' muscle protein synthesis processes using urea nitrogen salvage, they could be able to achieve better muscle health during long voyages into deep space in spacecraft too small for the usual exercise equipment, the argument goes.
"Because we know which muscle proteins are suppressed during spaceflight, we can compare these proteins with those that are enhanced by urea nitrogen salvage during hibernation," said Regan, who carried out this research while a postdoc at the University of Wisconsin-Madison.
Journal Reference:
Matthew D. Regan, Edna Chiang, Yunxi Liu , et al. Nitrogen recycling via gut symbionts increases in ground squirrels over the hibernation season, Science (DOI: 10.1126/science.abh2950)
Surveys with repetitive questions yield bad data, study finds:
The study found that people tire from questions that vary only slightly and tend to give similar answers to all questions as the survey progresses. Marketers, policymakers, and researchers who rely on long surveys to predict consumer or voter behavior will have more accurate data if they craft surveys designed to elicit reliable, original answers, the researchers suggest.
"We wanted to know, is gathering more data in surveys always better, or could asking too many questions lead to respondents providing less useful responses as they adapt to the survey," said first author Ye Li, a UC Riverside assistant professor of management. "Could this paradoxically lead to asking more questions but getting worse results?"
[...] In one of the studies, respondents were asked about their preferences for varying configurations of laptops. They were the sort of questions marketers use to determine if customers are willing to sacrifice a bit of screen size in return for increased storage capacity, for example.
"When you're asked questions over and over about laptop configurations that vary only slightly, the first two or three times you look at them carefully but after that maybe you just look at one attribute, such as how long the battery lasts. We use shortcuts. Using shortcuts gives you less information if you ask for too much information," said Li.
[...] "In as few as six or eight questions people are already answering in such a way that you're already worse off if you're trying to predict real-world behavior," said Li. "In these surveys if you keep giving people the same types of questions over and over, they start to give the same kinds of answers."
The findings suggest some tactics that can increase the validity of data while also saving time and money. Process-tracing, a research methodology that tracks not just the quantity of observations but also their quality, can be used to diagnose adaptation, helping to identify when it is a threat to validity. Adaptation could also be reduced or delayed by repeatedly changing the format of the task or adding filler questions or breaks. Finally, the research suggests that to maximize the validity of preference measurement surveys, researchers could use an ensemble of methods, preferably using multiple means of measurement, such as questions that involve choosing between options available at different times, matching questions, and a variety of contexts.
Journal Reference:
Y. Li, A. Krefeld-Schwalb, D. G. Wall, et al. Surveys with repetitive questions yield bad data, study finds Journal of Marketing Research (DOI: 10.1177/00222437211073581)
Microsoft Azure customer hit by largest 3.47 Tbps DDoS attack:
A Microsoft Azure cloud computing customer in Asia was a victim of a massive 3.47 Tbps DDoS attack (distributed denial of service attack) in November 2021, the software and technology giant Microsoft revealed on January 25, 2022.
The DDoS attack lasted approximately 15 minutes and included a botnet of more than 10,000 compromised IoT (Internet of Things) devices from countries across the globe. These included Iran, India, China, Russia, Taiwan, Vietnam, Thailand, Indonesia, South Korea, and the United States.
Attack vectors were UDP reflection on port 80 using Simple Service Discovery Protocol (SSDP), Connection-less Lightweight Directory Access Protocol (CLDAP), Domain Name System (DNS), and Network Time Protocol (NTP) comprising one single peak.
Alethea Toh Product Manager, Azure Networking
Microsoft's report further disclosed that there has been a surge in DDoS attacks with the United States and India being prime targets. The company noted that Hong Kong has also become a popular hotspot for attackers however there has been a decrease in DDoS activity in Europe.
[...] A DDoS attack involves sending a huge amount of illegal traffic from compromised machines to the intended target and therefore disrupting them completely. The system can crash and lead to a massive loss of data, particularly, in the case of companies that host a significant amount of information regarding their clients and customers.
The Prequel app is yassifying our selfies into hot cartoons:
If you're in need of a massive ego boost, this is your sign to turn yourself into a cartoon.
Twitter is currently full of people who are discovering the glorious effects of the Cartoon filter on the editing app Prequel. The free app takes any existing photo and turns it into a cartoon – simple, right? The cartoon animation effect isn't a new idea, but something about Prequel's version makes literally any photo a million times hotter.
[...] Of course, as with any viral app, we were curious about Prequel's privacy policy. The app doesn't make clear exactly what it does with the gorgeous selfies being uploaded, so there may be mild concern there.
[...] If you've decided to submit your personal data to the powers that be and really just want to get in on the hot cartoon fun, all you have to do is download the Prequel app on the App Store or Google Play store. Make sure to click out of the sneaky premium paid version that pops up when you first open the app, select the Cartoon filter, and choose a selfie to cartoonify. We found the effect works best with photos that only have one person and shows your face almost entirely.
[*] What Does It Mean to 'Yassify' Anything? at The New York Times.
Windows 11 frame rate stuttering reported by some users with AMD CPUs:
Some Windows 11 users are running into trouble with sporadic stuttering issues (accompanied with audio glitches), which according to reports are related to AMD processors and the necessary TPM [*] security required by Microsoft's newest operating system.
Specifically, on AMD PCs, there's an implementation of TPM which is fTPM – meaning it's integrated in firmware, rather than on a separate TPM module – and this is what folks who are affected believe is causing the issue, finding that when it's turned off in the BIOS, the stuttering disappears.
Unfortunately, some people don't have the option to turn off fTPM – that switch simply isn't present in the BIOS – so they're out of luck on that score. The other alternative solution appears to be installing a discrete TPM module, rather than relying on the firmware integrated functionality, and this also works to fix the issue – at least according to reports. Assuming you have the ability to install a separate TPM module in your PC.
[...] the stuttering frame rates hit at random times and last for a few seconds in some cases – longer in others – and audio is garbled at the same time.
If that should occur, say, during a crucial moment of an online game you're about to win, that's going to be pretty frustrating (and doubtless it'll be a serious annoyance as part of your everyday computing life, too).
[...] Essentially, turning off fTPM is something of a minefield of possible collateral damage on Windows 11, and that's why some of those who want to get around this stuttering glitch are downgrading to Windows 10.
This issue is hopefully something both Microsoft and AMD are putting their heads together to attempt to fix, so we can keep our fingers crossed that a proper resolution is delivered in the near future. If the glitches aren't disrupting your computing experience too much, likely your best bet is to sit tight and hope for the timely delivery of a patch.
[*] TPM (Trusted Platform Module) on Wikipedia.
A Crunching Multiverse To Solve Two Fundamental Physics Puzzles at Once:
A duo of theorists proposes a new theory to explain both the surprisingly small mass of the Higgs boson and the puzzling symmetry properties of the strong force.
The discovery of the Higgs boson was a landmark in the history of physics. It explained something fundamental: how elementary particles that have mass get their masses. But it also marked something no less fundamental: the beginning of an era of measuring in detail the particle's properties and finding out what they might reveal about the nature of the universe.
One such property is the particle's mass, which at 125 GeV is surprisingly small. Many theories have been put forward to explain this small mass, but none has so far been confirmed with data. In a paper just published in Physical Review Letters, Raffaele Tito D'Agnolo of the French Alternative Energies and Atomic Energy Commission (CEA) and Daniele Teresi of CERN propose a new theory to explain both the lightness of the Higgs boson and another fundamental physics puzzle.
In broad brushes, the duo's theory works like this. In its early moments, the universe is a collection of many universes each with a different value of the Higgs mass, and in some of these universes the Higgs boson is light. In this multiverse model, universes with a heavy Higgs boson collapse in a big crunch in a very short time, whereas universes with a light Higgs boson survive this collapse. Our present-day universe would be one of these surviving light-Higgs universes.
What's more, the model, which includes two new particles in addition to the known particles predicted by the Standard Model, can also explain the puzzling symmetry properties of the strong force, which binds quarks together into protons and neutrons, and protons and neutrons into atomic nuclei.
Although the theory of the strong force, known as quantum chromodynamics, predicts a possible breakdown in strong interactions of a fundamental symmetry called CP symmetry, such a breakdown is not observed in experiments. One of the new particles in D'Agnolo and Teresi's model can solve this so-called strong CP problem, making strong interactions CP symmetric. Moreover, the same new particle could also account for the dark matter that is thought to make up most of the matter in the universe.
Journal Reference:
Raffaele Tito D'Agnolo, Daniele Teresi. Sliding Naturalness: New Solution to the Strong-$CP$ and Electroweak-Hierarchy Problems [open], Physical Review Letters (DOI: 10.1103/PhysRevLett.128.021803)
Labor regulator accuses Amazon of intimidation as union drives move forward:
Amazon interrogated and surveilled warehouse workers in Staten Island, where some workers are seeking to form a union, prosecutors for the National Labor Relations Board said in a complaint Wednesday. The allegations come one day after the agency said the warehouse workers have collected enough signatures to move forward with a union election.
According to Bloomberg, the NLRB complaint alleges that an Amazon consultant promised to fix problems for workers if they opposed the union and called the workers leading the union push "thugs."
"Workers have the right under federal labor law to join and form unions and employers are prohibited from interfering with that right," said Kathy Drew King, the director of NLRB region 29, where the complaint originated. "The complaint seeks to stop and remedy this unlawful conduct to ensure that Amazon's employees can freely and fairly exercise their rights under the National Labor Relations Act."
Amazon spokesperson Kelly Nantel said the allegations are false, adding, "we look forward to showing that through this process."
The situation isn't Amazon's only union battle. In a separate organizing drive in Alabama, a union asked the labor board Wednesday to make Amazon get rid of a mailbox that the agency previously ruled tainted a union election last year. A redo election is scheduled for early February.
Amazon workers in Staten Island collect enough signatures to hold union vote:
Amazon workers at a warehouse in Staten Island have collected enough signatures to vote on unionizing, the National Labor Relations Board said Wednesday.
The union "reached a sufficient showing of interest," NLRB spokeswoman Kayla Blado confirmed.
[...] Amazon sought to cast doubt on the effort Wednesday.
"We're skeptical that there are a sufficient number of legitimate signatures, and we're seeking to understand how these signatures were verified," Amazon spokeswoman Kelly Nantel said in a statement. "Our employees have always had a choice of whether to join a union, and as we saw just a few months ago, the vast majority of our team in Staten Island did not support the ALU."
Amazon founder Jeff Bezos owns The Washington Post.
Look who's talking now: The fishes! Widespread sound communication among fish:
"We've known for a long time that some fish make sounds," said lead author Aaron Rice, a researcher at the K. Lisa Yang Center for Conservation Bioacoustics at the Cornell Lab of Ornithology. "But fish sounds were always perceived as rare oddities. We wanted to know if these were one-offs or if there was a broader pattern for acoustic communication in fishes."
The authors looked at a branch of fishes called the ray-finned fishes. These are vertebrates (having a backbone) that comprise 99% of the world's known species of fishes. They found 175 families that contain two-thirds of fish species that do, or are likely to, communicate with sound. By examining the fish family tree, study authors found that sound was so important, it evolved at least 33 separate times over millions of years.
"Thanks to decades of basic research on the evolutionary relationships of fishes, we can now explore many questions about how different functions and behaviors evolved in the approximately 35,000 known species of fishes," said co-author William E. Bemis '76, Cornell professor of ecology and evolutionary biology in the College of Agriculture and Life Sciences. "We're getting away from a strictly human-centric way of thinking. What we learn could give us some insight on the drivers of sound communication and how it continues to evolve."
The scientists used three sources of information: existing recordings and scientific papers describing fish sounds; the known anatomy of a fish -- whether they have the right tools for making sounds, such as certain bones, an air bladder, and sound-specific muscles; and references in 19th century literature before underwater microphones were invented.
Journal Reference:
Aaron N. Rice, Stacy C. Farina, Andrea J. Makowski, et al. Evolutionary Patterns in Sound Production across Fishes [open], Ichthyology & Herpetology (DOI: 10.1643/i2020172)
JEDEC Publishes HBM3 Update to High Bandwidth Memory (HBM) Standard:
JEDEC Solid State Technology Association, the global leader in the development of standards for the microelectronics industry, today announced the publication of the next version of its High Bandwidth Memory (HBM) DRAM standard: JESD238 HBM3, available for download from the JEDEC website. HBM3 is an innovative approach to raising the data processing rate used in applications where higher bandwidth, lower power consumption and capacity per area are essential to a solution's market success, including graphics processing and high-performance computing and servers.
Key attributes of the new HBM3 include:
- Extending the proven architecture of HBM2 towards even higher bandwidth, doubling the per-pin data rate of HBM2 generation and defining data rates of up to 6.4 Gb/s, equivalent to 819 GB/s per device
- Doubling the number of independent channels from 8 (HBM2) to 16; with two pseudo channels per channel, HBM3 virtually supports 32 channels
- Supporting 4-high, 8-high and 12-high TSV stacks with provision for a future extension to a 16-high TSV stack
- Enabling a wide range of densities based on 8Gb to 32Gb per memory layer, spanning device densities from 4GB (8Gb 4-high) to 64GB (32Gb 16-high); first generation HBM3 devices are expected to be based on a 16Gb memory layer
- Addressing the market need for high platform-level RAS (reliability, availability, serviceability), HBM3 introduces strong, symbol-based ECC on-die, as well as real-time error reporting and transparency
- Improved energy efficiency by using low-swing (0.4V) signaling on the host interface and a lower (1.1V) operating voltage
"With its enhanced performance and reliability attributes, HBM3 will enable new applications requiring tremendous memory bandwidth and capacity," said Barry Wagner, Director of Technical Marketing at NVIDIA and JEDEC HBM Subcommittee Chair.
Players needed to solve puzzles and help advance cancer research:
The game, out today on iOS and Android and available in English, Spanish, Catalan and Italian, is the result of a two-and-a-half-year long citizen science project developed by a team of researchers at the Centre for Genomic Regulation (CRG), the Centro Nacional de Análisis Genómico (CNAG-CRG) and game professionals.
The game was created to boost worldwide research efforts that depend on cancer cell lines, a critical resource used by scientists to study cancer and test new drugs to treat the disease. One of the limitations of cancer cell lines are a lack of high-resolution genome reference maps, which are necessary to help researchers interpret their scientific results, for example pinpointing the location of genes of therapeutic interest or potential mutation sites.
[...] To play GENIGMA, players have to solve a puzzle involving a string of blocks of different colours and shapes. Each string represents a genetic sequence in the cancer cell line, and how players organise the blocks is a potential solution to the location of genes.
Players have to reorganise the blocks so that they attain the highest-score possible. The higher the number of players and high scores, the higher likelihood that researchers have found the correct sequence for this particular location in the reference map.
"Anyone with a smartphone from anywhere in the world can download GENIGMA for free and make a direct contribution to research, lending their logic and dexterity to the service of science," says Elisabetta Broglio, citizen science facilitator at the CRG. "GENIGMA will analyze the solutions provided by the players as a collective and not as individuals, and will take advantage of creative solutions impossible to find with deterministic algorithms."
The first genome reference map researchers will attempt to solve is for the T-47D breast cancer cell line, one of the most commonly used resources in cancer research. GENIGMA's research team estimate that 30 thousand players solving an average of 50 games each would generate enough data to reveal the reference map of the 20,000 genes in this breast cancer cell line.
The game launches today with a three-month long campaign -- the #GenigmaChallenge. Every week on Monday, for a total period of three months, the GENIGMA team will introduce new genome fragments from the T-47D cell line to be arranged by players. The first genome fragments needing to be arranged are from chromosome 17, which contain a high number of breast cancer related genes. This includes BRCA1, for which mutations have been associated with about 40% of inherited breast cancer.
The increase occurred during a period when some studies reported overall progress in blood pressure control and a decline in related cardiovascular events in the U.S. The findings are published in the Journal of the American Heart Association.
"Although more people have been able to manage their blood pressure over the last few years, we're not seeing this improvement translate into fewer hospitalizations for hypertensive crisis[*]," said Joseph E. Ebinger, MD, a clinical cardiologist and director of clinical analytics at the Smidt Heart Institute and first author of the study.
[...] To conduct their study, the investigators analyzed data from the National Inpatient Sample, a publicly available database. The data include a subset of all hospitalizations across the U.S., providing a picture of nationwide trends. They found that annual hospitalizations for hypertensive crises more than doubled over a 13-year period. Hospitalizations related to hypertensive crises represented 0.17% of all admissions for men in 2002 but 0.39% in 2014. Hospitalizations related to hypertensive crisis represented 0.16% of all admissions for women in 2002 but 0.34% in 2014.
The investigators estimated that from 2002 to 2014, there were 918,392 hospitalizations and 4,377 in-hospital deaths related to hypertensive crisis across the U.S.
The risk of dying from a hypertensive crisis, however, did decrease slightly overall during the studied time period. Women died at the same rate as men, even though they had fewer health issues than men who also were hospitalized for a hypertensive crisis.
[*] Hypertensive crisis on Wikipedia.
Journal Reference:
Joseph E. Ebinger, Yunxian Liu, PhD, MS, Matthew Driver, MPH et al. Sex‐Specific Temporal Trends in Hypertensive Crisis Hospitalizations in the United States, Journal of the American Heart Association (DOI: 10.1161/JAHA.121.021244)
Crowding, climate change, and the case for social distancing among trees:
For many, an ideal forest is one that looks the same as it did before European colonizers arrived. [...] Managers need to consider new strategies for building resilient forests, according to Tucker Furniss and Jim Lutz, from Utah State University's Department of Wildland Resources in the S.J. & Jessie E. Quinney College of Natural Resources.
[...] Recreating historical conditions has been a key strategy for restoration efforts, but today's novel conditions require different strategies. Specifically, the research shows that lower crowding for trees can increase chances of survival after fire. Results from two long-term studies (covering 23 years and more than 50,000 individual trees) show that chances for long-term tree survival increased when trees had more space, by reducing competition and helping trees recover from fire more quickly.
Over the years, the team performed tens of thousands of post-mortems on dead trees in the Sierra Nevada mountains to identify the cause of demise. They analyzed data and found that in crowded forests, trees were less tolerant of fire damage, and were more susceptible to post-fire bark beetle attack. In more open forests, though, trees could tolerate higher levels of fire damage, even when fire burned during extreme drought. [...] Alleviating the stress that occurs when close neighbors compete for limited water resources lets trees use sap to fend off beetle attacks, and it helps them heal after fire.
[...] "Using historical conditions as an ideal example of a healthy forest may not be practical moving forward," Furniss said. Forests from the pre-settlement era had their own problems after all, he said. And even if those ecosystems were successful at overcoming the disturbances of their time, those evolutionary strategies don't necessarily translate to resilience today, in a world defined by climate change.
Journal Reference:
Tucker J. Furniss, Adrian J. Das, Phillip J. van Mantgem, et al. Crowding, climate, and the case for social distancing among trees, Ecological Applications (DOI: 10.1002/eap.2507)
Australia scientists find 'spooky' spinning object in Milky Way:
Australian scientists say they have discovered an unknown spinning object in the Milky Way that they claim is unlike anything seen before.
The object - first discovered by a university student - has been observed to release a huge burst of radio energy for a full minute every 18 minutes. Objects that pulse energy in the universe are often documented. But researchers say something that turns on for a minute is highly unusual.
The team is working to understand more. The object was first discovered by Curtin University Honours student Tyrone O'Doherty in a region of the Western Australian outback known as the Murchison Widefield Array, using a telescope and a new technique he had developed.
[...] Theories around what the object might be include a neutron star or a white dwarf - a term used for the remnants of a collapsed star. However, much of the discovery remains a mystery.
"More detections will tell astronomers whether this was a rare one-off event or a vast new population we'd never noticed before," Dr Hurley-Walker said. "I'm looking forward to understanding this object and then extending the search to find more."
Neutron star on Wikipedia.
White dwarf on Wikipedia.
Also at ICRAR (International Centre for Radio Astronomy Research) which has informative depictions and a link to a video on YouTube.
MPs to debate landmark IoT security law:
The proposed Product Security and Telecoms Infrastructure Bill will receive its second reading in the House of Commons today in a debate to be opened by current digital secretary Nadine Dorries, as it takes a significant step forward towards becoming law.
The bill – which mandates improved cyber protections for smartphones and other smart or connected internet of things (IoT) devices – has been years in the making. Its scope has expanded over time to include new provisions that will supposedly spur the roll-out of full-fibre broadband services by making it easier for operators to upgrade and share infrastructure, and reform the process of how they go about negotiating with landowners to whose property they need access.
At its core it places strict new requirements on the manufacturers and retailers of connected consumer technology, banning easy-to-guess default passwords programmed onto devices, creating a vulnerability-reporting system, and forcing manufacturers to be upfront about how long their products will receive security updates.
Failure to comply could result in fines of up to £10m, or 4% of global turnover, and up to £20,000 for every day in the case of ongoing breaches.
“Whether it’s your phone, smart speaker or fitness tracker, it’s vital that these devices are kept secure from cyber criminals,” said Dorries.
“Every product on our shelves has to meet all sorts of minimum requirements, like being fire resistant or [noting if it’s] a choking hazard, and this is no different for the digital age where products can now carry a cyber security risk.
“We are legislating to protect people across the UK and keep pace with technology as it transforms our everyday lives,” she said.
The bill will apply to any device that can access the internet, including smartphones and smart TVs, games consoles, security cameras and connected alarms, smart toys and baby monitoring kit, smart home hubs and voice activated assistants (such as Alexa) and connected appliances such as washing machines and fridges.
US Navy wants to get crashed stealth fighter back -- before China can:
US Navy wants to get crashed stealth fighter back -- before China can
The F-35C, a single-engine stealth fighter and the newest jet in the US Navy fleet, crash-landed on the aircraft carrier USS Carl Vinson during routine operations on Monday, the Navy said.
The $100 million warplane impacted the flight deck of the 100,000-ton aircraft carrier and then fell into the sea as its pilot ejected, Navy officials said. The pilot and six sailors aboard the Vinson were injured.
While damage to the Vinson was only superficial, and it and the carrier's air wing have resumed normal operations, the Navy faces the daunting task of attempting to pull the F-35 off the ocean floor in some of the most contested waters on the planet.
The Navy is giving scant details on its recovery plans for the F-35C, the first of which only became operational in 2019.